General information for g10026.t7
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1.
Parent gene
- The parent gene g10026 is located on chr_1: 6798067..6798782 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10026 | g10026.t7 | isoform | g10026.t7 | 6798067 | 6798782 |
| chr_1 | g10026 | g10026.t7 | exon | g10026.t7.exon1 | 6798067 | 6798562 |
| chr_1 | g10026 | g10026.t7 | cds | g10026.t7.CDS1 | 6798172 | 6798562 |
| chr_1 | g10026 | g10026.t7 | exon | g10026.t7.exon2 | 6798622 | 6798782 |
| chr_1 | g10026 | g10026.t7 | cds | g10026.t7.CDS2 | 6798622 | 6798782 |
| chr_1 | g10026 | g10026.t7 | TTS | g10026.t7 | 6799073 | 6799073 |
| chr_1 | g10026 | g10026.t7 | TSS | g10026.t7 | NA | NA |
Sequences
>g10026.t7 Gene=g10026 Length=657
TTCTTACGCTACCATCGTAATCAAATAAGCCGCGTTTATCCAAAAGGCCAACGTCTCGAC
TCATCAAACTTTAATCCATTGCCGTTTTGGAACATTGGCTCCCAAATGATTGCTCTCAAT
TTCCAAACTCCTGATAAGCCCATGCAAATTTTAATGGGAAAGTTTCGAGATAACGGTGGA
TGTGGATTTCTGTTGAAACCCGAGTTTATGCTACGTGATGATTTTGATCCAAATGATGCA
TCATTCGATGGCTTGGATCAAGTTCTCGTTACAATACGTATTATTGCTGCACGGCATCTA
TTTAAAAGTGGGCGCACCAATATATCAAGCCCATTGGTTGAAATTGAAGTGCTTGGCGCG
CCTTTTGATACTGGAATCAAACATCGAACGAAAGCCATTTCTGATAATGGCTTTAATCCG
ATTTGGAATGAAATATGTGAATTTAGAATTAGAAATTCTGCATTTGCTTTATTACGTTTT
GAGGTGCAAGACGAAGACATGTTTGGCGAGAAGAATATGATCGGACAGGCAGTTTTTCCA
ATCAATTGTCTCCGCACTGGCTATCGAAGTGTTCCATTAAGAAATAAATACAGCGAAGAA
CTTGAATTGGCTGCACTTCTTGTACATTTTGCAATAAAACAAGTCAAAGAGTACTAA
>g10026.t7 Gene=g10026 Length=183
MIALNFQTPDKPMQILMGKFRDNGGCGFLLKPEFMLRDDFDPNDASFDGLDQVLVTIRII
AARHLFKSGRTNISSPLVEIEVLGAPFDTGIKHRTKAISDNGFNPIWNEICEFRIRNSAF
ALLRFEVQDEDMFGEKNMIGQAVFPINCLRTGYRSVPLRNKYSEELELAALLVHFAIKQV
KEY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g10026.t7 | CDD | cd00275 | C2_PLC_like | 53 | 178 | 0.000 |
| 8 | g10026.t7 | Gene3D | G3DSA:3.20.20.190 | Phosphatidylinositol (PI) phosphodiesterase | 1 | 45 | 0.000 |
| 9 | g10026.t7 | Gene3D | G3DSA:2.60.40.150 | - | 46 | 183 | 0.000 |
| 3 | g10026.t7 | PANTHER | PTHR10336:SF159 | 1-PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA | 1 | 177 | 0.000 |
| 4 | g10026.t7 | PANTHER | PTHR10336 | PHOSPHOINOSITIDE-SPECIFIC PHOSPHOLIPASE C FAMILY PROTEIN | 1 | 177 | 0.000 |
| 2 | g10026.t7 | Pfam | PF00387 | Phosphatidylinositol-specific phospholipase C, Y domain | 1 | 34 | 0.000 |
| 1 | g10026.t7 | Pfam | PF00168 | C2 domain | 55 | 152 | 0.000 |
| 11 | g10026.t7 | ProSiteProfiles | PS50008 | Phosphatidylinositol-specific phospholipase Y-box domain profile. | 1 | 35 | 17.604 |
| 10 | g10026.t7 | ProSiteProfiles | PS50004 | C2 domain profile. | 43 | 143 | 15.799 |
| 7 | g10026.t7 | SMART | SM00239 | C2_3c | 54 | 158 | 0.000 |
| 5 | g10026.t7 | SUPERFAMILY | SSF51695 | PLC-like phosphodiesterases | 1 | 44 | 0.000 |
| 6 | g10026.t7 | SUPERFAMILY | SSF49562 | C2 domain (Calcium/lipid-binding domain, CaLB) | 55 | 177 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008081 | phosphoric diester hydrolase activity | MF |
| GO:0007165 | signal transduction | BP |
| GO:0004435 | phosphatidylinositol phospholipase C activity | MF |
| GO:0035556 | intracellular signal transduction | BP |
| GO:0006629 | lipid metabolic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
