General information for g10145.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Mannose-6-phosphate isomerase.
Parent gene
- The parent gene g10145 is located on chr_1: 7764109..7766532 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10145 | g10145.t1 | TSS | g10145.t1 | 7762722 | 7762722 |
| chr_1 | g10145 | g10145.t1 | isoform | g10145.t1 | 7762798 | 7764109 |
| chr_1 | g10145 | g10145.t1 | exon | g10145.t1.exon1 | 7762798 | 7763166 |
| chr_1 | g10145 | g10145.t1 | cds | g10145.t1.CDS1 | 7762798 | 7763166 |
| chr_1 | g10145 | g10145.t1 | exon | g10145.t1.exon2 | 7763228 | 7763623 |
| chr_1 | g10145 | g10145.t1 | cds | g10145.t1.CDS2 | 7763228 | 7763623 |
| chr_1 | g10145 | g10145.t1 | exon | g10145.t1.exon3 | 7763681 | 7764109 |
| chr_1 | g10145 | g10145.t1 | cds | g10145.t1.CDS3 | 7763681 | 7764109 |
| chr_1 | g10145 | g10145.t1 | TTS | g10145.t1 | 7764172 | 7764172 |
Sequences
>g10145.t1 Gene=g10145 Length=1194
ATGGAGATTTTTGGTGATATTAAAAATTATGATTGGGGAAAATTAGGTGGAGAGAGTGAA
GTTGTGAAATTGGTGCAATTAAATGATGATTCATTTGTTGTTGACAATAAAAAGCCATAT
TCTGAGTTATGGATGGGCGATCATGTCTCTGGACCATCAAAAGTTAAAGCAACTGGTGAA
AGTCTTGGTGAATTTATACAAAAAGACCTCAAGGGAAATATTGGTGGACAAGCAAAACTC
CCATTTCTTTTTAAAGTGCTTAGCATTAGAAAAGCTTTGAGCATTCAAGTTCATCCTAAT
AAGTCTGAAGCTGAACGCTTACATTCGCTTTATCCTGATATCTATAAAGATGCGAATCAC
AAGCCCGAGATTGCAATTGCATTGACACCGTTTCTAGCGTTATGTGATTTTCGTCCACAC
GGTGAGATCTATCAACTTTTGAAATCTCATAATGAACTCGTTGAACTCTTGGGTAGTGGC
AATATTGACTTAATTAATTCTAATGGAGCTGATGGATTGAAGATGTGCTACAGTAAACTT
ATGAAATGTGATGATACTAGCATTCGCAAGTGCATTGACTCGCTTACTGACAAATTTAAA
AATGATAACAGCAAACTTGCTGAAGTGTTCAATCAAATTCAAAAAGATTTTCCATATGAT
GTTGGTTCATTGTCGTTGTTTTTCTTGAATCTTATTGAAATGAAACCTGGACAGTCAATT
TATTTGGCAGCTAAAATTCCTCATGCTTATCTTTTTGGTGATTGTATTGAATGCATGAGT
TGTTCCGATAACGTCGTTAGAGCTGGACTAACACCAAAGTTCAAAGATGTTGAGAATTTA
CTTAGCATGTTGATTTATGATGGAAGAAATGCAAATGAAATTCTTTTTAAACCAGAAATG
ATTGATGAAAAACATCAATTTACTTCACTCTTTCGACCACCAATAGATGACTTTGCTGTG
GCAAAAGTTGAAATTCCTCAAAGTGTCAAAGACTACGAAATTGTCAATAGCAAATTTGGG
TCAATTATTTTAGTGATTTCTGGCAGTGCAATAATGTCTGCATCTGGTATGGAGACATTA
AACATCAAAAGAGGCTCAATTATTTTCGTGCCATCGAGTGTCGGTCCTTCACTGAAATTG
TCCAACATTGAAAACAATCTCATTTGCTATCAAGCAATGTACAATGATTTTTAA
>g10145.t1 Gene=g10145 Length=397
MEIFGDIKNYDWGKLGGESEVVKLVQLNDDSFVVDNKKPYSELWMGDHVSGPSKVKATGE
SLGEFIQKDLKGNIGGQAKLPFLFKVLSIRKALSIQVHPNKSEAERLHSLYPDIYKDANH
KPEIAIALTPFLALCDFRPHGEIYQLLKSHNELVELLGSGNIDLINSNGADGLKMCYSKL
MKCDDTSIRKCIDSLTDKFKNDNSKLAEVFNQIQKDFPYDVGSLSLFFLNLIEMKPGQSI
YLAAKIPHAYLFGDCIECMSCSDNVVRAGLTPKFKDVENLLSMLIYDGRNANEILFKPEM
IDEKHQFTSLFRPPIDDFAVAKVEIPQSVKDYEIVNSKFGSIILVISGSAIMSASGMETL
NIKRGSIIFVPSSVGPSLKLSNIENNLICYQAMYNDF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g10145.t1 | CDD | cd07011 | cupin_PMI_type_I_N | 3 | 286 | 2.21364E-112 |
| 14 | g10145.t1 | Gene3D | G3DSA:2.60.120.10 | Jelly Rolls | 5 | 268 | 1.4E-125 |
| 12 | g10145.t1 | Gene3D | G3DSA:1.10.441.10 | Phosphomannose Isomerase | 139 | 293 | 1.4E-125 |
| 13 | g10145.t1 | Gene3D | G3DSA:2.60.120.10 | Jelly Rolls | 294 | 392 | 1.4E-125 |
| 2 | g10145.t1 | PANTHER | PTHR10309 | MANNOSE-6-PHOSPHATE ISOMERASE | 6 | 395 | 3.9E-118 |
| 15 | g10145.t1 | PIRSF | PIRSF001480 | PMI | 1 | 396 | 7.5E-124 |
| 5 | g10145.t1 | PRINTS | PR00714 | Phosphomannose isomerase type I signature | 3 | 21 | 6.5E-69 |
| 7 | g10145.t1 | PRINTS | PR00714 | Phosphomannose isomerase type I signature | 39 | 54 | 6.5E-69 |
| 4 | g10145.t1 | PRINTS | PR00714 | Phosphomannose isomerase type I signature | 80 | 101 | 6.5E-69 |
| 3 | g10145.t1 | PRINTS | PR00714 | Phosphomannose isomerase type I signature | 115 | 138 | 6.5E-69 |
| 8 | g10145.t1 | PRINTS | PR00714 | Phosphomannose isomerase type I signature | 213 | 228 | 6.5E-69 |
| 6 | g10145.t1 | PRINTS | PR00714 | Phosphomannose isomerase type I signature | 229 | 248 | 6.5E-69 |
| 9 | g10145.t1 | PRINTS | PR00714 | Phosphomannose isomerase type I signature | 248 | 267 | 6.5E-69 |
| 10 | g10145.t1 | PRINTS | PR00714 | Phosphomannose isomerase type I signature | 267 | 286 | 6.5E-69 |
| 1 | g10145.t1 | Pfam | PF01238 | Phosphomannose isomerase type I | 7 | 355 | 7.2E-94 |
| 17 | g10145.t1 | ProSitePatterns | PS00965 | Phosphomannose isomerase type I signature 1. | 115 | 123 | - |
| 11 | g10145.t1 | SUPERFAMILY | SSF51182 | RmlC-like cupins | 6 | 378 | 6.23E-99 |
| 18 | g10145.t1 | TIGRFAM | TIGR00218 | manA: mannose-6-phosphate isomerase, class I | 3 | 376 | 7.7E-76 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008270 | zinc ion binding | MF |
| GO:0005975 | carbohydrate metabolic process | BP |
| GO:0004476 | mannose-6-phosphate isomerase activity | MF |
| GO:0009298 | GDP-mannose biosynthetic process | BP |
KEGG
Orthology
- This transcript has been annotated with K01809 (mannose-6-phosphate isomerase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
