General information for g10146.t8
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative FERM, ARHGEF and pleckstrin domain-containing protein 2.
Parent gene
- The parent gene g10146 is located on chr_1: 7781300..7782838 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10146 | g10146.t8 | isoform | g10146.t8 | 7765500 | 7766532 |
| chr_1 | g10146 | g10146.t8 | exon | g10146.t8.exon1 | 7765500 | 7765513 |
| chr_1 | g10146 | g10146.t8 | cds | g10146.t8.CDS1 | 7765502 | 7765513 |
| chr_1 | g10146 | g10146.t8 | exon | g10146.t8.exon2 | 7765837 | 7766142 |
| chr_1 | g10146 | g10146.t8 | cds | g10146.t8.CDS2 | 7765837 | 7766142 |
| chr_1 | g10146 | g10146.t8 | exon | g10146.t8.exon3 | 7766204 | 7766532 |
| chr_1 | g10146 | g10146.t8 | cds | g10146.t8.CDS3 | 7766204 | 7766437 |
| chr_1 | g10146 | g10146.t8 | TSS | g10146.t8 | NA | NA |
| chr_1 | g10146 | g10146.t8 | TTS | g10146.t8 | NA | NA |
Sequences
>g10146.t8 Gene=g10146 Length=649
ATTATCATGGTATAAACGGATCATTGGATAGAAGAAGTGATCTAACATCACCATCTTTAA
ATAGATATGACTTGACCATTGGTTCAGATAAATCGATGTCATATGACCTTGCAGAAGCAG
AAAAAAATAATCAGAATAATACAATTGGAATTATCACAGCAACATCACCGACATCAATTG
GTATTACGCAAACAAACAGTATTGTCAACACATTAGAAAGAAATGATACACTAAGGAAAA
AATGGCCAACAGATAAAGCATATTATATCAGTAAAGAAATTCTTATGACTGAGAGAACAT
ATAGACGTGACTTGGATGTTATTAATGTGCGTTATAGAAAAATCTTGGCACCAGAAGACA
TTGAAAATCTCCAACCACTTTTTGACTATTTCGAATCTATGGTGCAACATCATTCAATTT
TCTTACGAGACCTCGAACATCGCATAGTTATGTGGGAATCACGAGGTGATGAAGTTAAAA
CACGCATTGGTGATGTAATGTTGAAAAACATGGTTGTGTTACCAATTTATGAAGAGTACT
TTGAGTATCATCGCGAAATTCTTCAGCGACTTAATGACCTCTTCAATGCTGATGAACGTT
TTCAACAGATATATAAAGATTTAGAGCAAGAGAAGGTGTGCTATCTACC
>g10146.t8 Gene=g10146 Length=184
MSYDLAEAEKNNQNNTIGIITATSPTSIGITQTNSIVNTLERNDTLRKKWPTDKAYYISK
EILMTERTYRRDLDVINVRYRKILAPEDIENLQPLFDYFESMVQHHSIFLRDLEHRIVMW
ESRGDEVKTRIGDVMLKNMVVLPIYEEYFEYHREILQRLNDLFNADERFQQIYKDLEQEK
VCYL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g10146.t8 | Gene3D | G3DSA:1.20.900.10 | - | 50 | 184 | 0.00 |
| 2 | g10146.t8 | PANTHER | PTHR45858 | FERM DOMAIN CONTAINING PROTEIN | 24 | 184 | 0.00 |
| 3 | g10146.t8 | PANTHER | PTHR45858:SF4 | FERM, ARHGEF AND PLECKSTRIN DOMAIN-CONTAINING PROTEIN 2 | 24 | 184 | 0.00 |
| 1 | g10146.t8 | Pfam | PF00621 | RhoGEF domain | 59 | 182 | 0.00 |
| 6 | g10146.t8 | ProSiteProfiles | PS50010 | Dbl homology (DH) domain profile. | 54 | 184 | 15.74 |
| 4 | g10146.t8 | SUPERFAMILY | SSF48065 | DBL homology domain (DH-domain) | 45 | 182 | 0.00 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005085 | guanyl-nucleotide exchange factor activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
