General information for g10177.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Putative glutathione-specific gamma-glutamylcyclotransferase 2.
Parent gene
- The parent gene g10177 is located on chr_1: 8079769..8080957 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10177 | g10177.t1 | TTS | g10177.t1 | 8079748 | 8079748 |
| chr_1 | g10177 | g10177.t1 | isoform | g10177.t1 | 8079769 | 8080423 |
| chr_1 | g10177 | g10177.t1 | exon | g10177.t1.exon1 | 8079769 | 8080299 |
| chr_1 | g10177 | g10177.t1 | cds | g10177.t1.CDS1 | 8079769 | 8080299 |
| chr_1 | g10177 | g10177.t1 | exon | g10177.t1.exon2 | 8080358 | 8080423 |
| chr_1 | g10177 | g10177.t1 | cds | g10177.t1.CDS2 | 8080358 | 8080423 |
| chr_1 | g10177 | g10177.t1 | TSS | g10177.t1 | 8080519 | 8080519 |
Sequences
>g10177.t1 Gene=g10177 Length=597
ATGGATAGTGTGAATAACATTTGCCAAAATTGTAATGAACTTTGGGTCTTTGGTTATGGA
TCATTGGTATGGAAGAATGCAGATTTTGAATTCGAAAGCAGTGTTGCAGGATTTTTAAAA
GGATTCAAAAGACGCTTTTATCAAAATAGCATTGATCATAGAGGAACAGAAAAATTTCCA
GGTCGTGTTGTTACGTTAATCAAGAGTGACGATCAAAATGAGAGAGTATATGGAATGGGT
TATAAAATTTCAAATGACAAAATCATGAAAGTACTTAATCATTTAGACTATCGCGAAAAA
AATGGATATGAACGCTGTGAAACATTTTTCTATCCTATCAATAATGAACAGCTCAAAAAG
AAGACTATAGTTTATGTGGCAAATGAGACTAATCCATCATGGAATAGTGATCATGATTTA
CATTCTATTGCTCGTCAAGTATTTAAAGCCATTGGACCATCAGGTGATAATATTTCATAT
GTTTATAATCTCTGCAATGCAATGAGAGAGCATTTTCCAAATCATTATCATGAAGATAGG
CATCTTTTTGAACTTGAAAAATTACTCAAAGAAATGAAAGAGAAGGCTAGTGAATAA
>g10177.t1 Gene=g10177 Length=198
MDSVNNICQNCNELWVFGYGSLVWKNADFEFESSVAGFLKGFKRRFYQNSIDHRGTEKFP
GRVVTLIKSDDQNERVYGMGYKISNDKIMKVLNHLDYREKNGYERCETFFYPINNEQLKK
KTIVYVANETNPSWNSDHDLHSIARQVFKAIGPSGDNISYVYNLCNAMREHFPNHYHEDR
HLFELEKLLKEMKEKASE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g10177.t1 | CDD | cd06661 | GGCT_like | 16 | 127 | 0 |
| 5 | g10177.t1 | Gene3D | G3DSA:3.10.490.10 | Hypothetical upf0131 protein ytfp | 5 | 197 | 0 |
| 2 | g10177.t1 | PANTHER | PTHR12192:SF20 | GLUTATHIONE-SPECIFIC GAMMA-GLUTAMYLCYCLOTRANSFERASE 2 | 6 | 196 | 0 |
| 3 | g10177.t1 | PANTHER | PTHR12192 | CATION TRANSPORT PROTEIN CHAC-RELATED | 6 | 196 | 0 |
| 1 | g10177.t1 | Pfam | PF04752 | ChaC-like protein | 14 | 191 | 0 |
| 4 | g10177.t1 | SUPERFAMILY | SSF110857 | Gamma-glutamyl cyclotransferase-like | 14 | 135 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0003839 | gamma-glutamylcyclotransferase activity | MF |
| GO:0006751 | glutathione catabolic process | BP |
KEGG
Orthology
- This transcript has been annotated with K07232 (glutathione-specific gamma-glutamylcyclotransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
