General information for g10199.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Soluble guanylate cyclase 88E.
Parent gene
- The parent gene g10199 is located on chr_1: 8183642..8191400 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10199 | g10199.t2 | isoform | g10199.t2 | 8183193 | 8185504 |
| chr_1 | g10199 | g10199.t2 | exon | g10199.t2.exon1 | 8183193 | 8183404 |
| chr_1 | g10199 | g10199.t2 | exon | g10199.t2.exon2 | 8183540 | 8183809 |
| chr_1 | g10199 | g10199.t2 | cds | g10199.t2.CDS1 | 8183642 | 8183809 |
| chr_1 | g10199 | g10199.t2 | exon | g10199.t2.exon3 | 8184866 | 8185041 |
| chr_1 | g10199 | g10199.t2 | cds | g10199.t2.CDS2 | 8184866 | 8185041 |
| chr_1 | g10199 | g10199.t2 | exon | g10199.t2.exon4 | 8185320 | 8185395 |
| chr_1 | g10199 | g10199.t2 | cds | g10199.t2.CDS3 | 8185320 | 8185395 |
| chr_1 | g10199 | g10199.t2 | exon | g10199.t2.exon5 | 8185475 | 8185504 |
| chr_1 | g10199 | g10199.t2 | cds | g10199.t2.CDS4 | 8185475 | 8185504 |
| chr_1 | g10199 | g10199.t2 | TSS | g10199.t2 | NA | NA |
| chr_1 | g10199 | g10199.t2 | TTS | g10199.t2 | NA | NA |
Sequences
>g10199.t2 Gene=g10199 Length=764
AGTAGTATTTAGTTGAACTAATGAAAAGGTATATTTTTCCAGAACGTGCAAGATTATTGT
AACCGAGGATTAGCAGGATTATTTTGTGTTCTCACAACTTACATATATATGCGTGTGGTT
TTATTTTGAATAAAATTATACAAAGAAGAATATTGTTAAAATTTTAATTCAATGAAAAAT
AAAAAGAAAATGTTATTGATATAGTATAGTATCAATAAGTTCAAAGAGCTATAAAAAGTG
AAAACTAAAGCTTGCAAAACGAAATAAACATATTTAAGTTTTGCACTCTATTCAACTTTC
TCGTATGAGAAGCAATGTATGGTTTACTGCTAGAAAATTTAGCAGAATATGTTAAAGCAT
ACTATGGTGACGAAAAGTGGGATGAAGTACGACGTCAGGCTGGCATATCATCAACTTCAT
TCAGTGTTCACGAAGACTACGATGAAGATCTGCTCAATCGGCTAGCAGCAACCGCACAAA
ATCTTCTTGGTGTATCAGAGTCAGAGTTCATGGACCAAATGGGTGTTTACTTTGTAAACT
TTGTCGGCCAGTATGGATATGATCGTGTTCTATCAGTTCTCGGACGACATATGAGAGATT
TCTTAAATGGCTTAGACAATCTTCATGAATATCTCAAATTTAGCTATCCAATGATGAGAG
CGCCATCATTTTTTTGTGAGAATGAAACGCGACATGGCTTGACGCTACATTATCGCACAA
GGAGAAAAGGCTTTGTTTACTATACAATGGGACAAATTAGACAA
>g10199.t2 Gene=g10199 Length=150
MYGLLLENLAEYVKAYYGDEKWDEVRRQAGISSTSFSVHEDYDEDLLNRLAATAQNLLGV
SESEFMDQMGVYFVNFVGQYGYDRVLSVLGRHMRDFLNGLDNLHEYLKFSYPMMRAPSFF
CENETRHGLTLHYRTRRKGFVYYTMGQIRQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g10199.t2 | Gene3D | G3DSA:3.90.1520.10 | - | 1 | 150 | 0 |
| 2 | g10199.t2 | PANTHER | PTHR45655 | GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2 | 2 | 150 | 0 |
| 3 | g10199.t2 | PANTHER | PTHR45655:SF10 | SOLUBLE GUANYLATE CYCLASE 88E | 2 | 150 | 0 |
| 1 | g10199.t2 | Pfam | PF07700 | Haem-NO-binding | 2 | 150 | 0 |
| 4 | g10199.t2 | SUPERFAMILY | SSF111126 | Ligand-binding domain in the NO signalling and Golgi transport | 1 | 150 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0020037 | heme binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed