General information for g10206.t8
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative apoptosis-inducing factor 1, mitochondrial.
Parent gene
- The parent gene g10206 is located on chr_1: 8212258..8213277 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10206 | g10206.t8 | isoform | g10206.t8 | 8211015 | 8212258 |
| chr_1 | g10206 | g10206.t8 | exon | g10206.t8.exon1 | 8211015 | 8211749 |
| chr_1 | g10206 | g10206.t8 | cds | g10206.t8.CDS1 | 8211347 | 8211749 |
| chr_1 | g10206 | g10206.t8 | exon | g10206.t8.exon2 | 8211813 | 8212258 |
| chr_1 | g10206 | g10206.t8 | cds | g10206.t8.CDS2 | 8211813 | 8212258 |
| chr_1 | g10206 | g10206.t8 | TTS | g10206.t8 | 8212421 | 8212421 |
| chr_1 | g10206 | g10206.t8 | TSS | g10206.t8 | NA | NA |
Sequences
>g10206.t8 Gene=g10206 Length=1181
AGGGATATACTGTGACAAAACTTAATGTTAATGAACAAAAAGTTCTCTTAGATGATGGCA
CAGAAATTACATATGATAAATGTTTGTTAGCTACAGGTAGTTCTCCAAAGACACTTCGCA
TATTCGATAGCGCATCGCCAAAAATAAAAGAAAAGATTTTTACATATAAAAGTGTGAAAG
ATTTCGAACTTGTGAAAAAACAAGTGGAAAAATCAAAGAATGTAGCTATTGTGGGAAATG
GCTTCTTAGGAAGTGAATTAGCTTGTGCTTTATCTCATTATGGAACTTTAAATGATTTAA
AAGTAGTTCAACTATTTCCTGAAAGTGGCAATATGGCAAAAGTGTTGCCAAAATATTTGA
GTGAATGGGCCACTGAAAGAATAAGAGATGTGGGTGTAAATGTTTTACCAAATAGTCAAA
TAGTTAATGTAGAACTTTTCAATGGAAACCAAATTAAATTGATACTTAACAACGGAAATA
GTATAATAGCTGATTTTGTTATTCAAGCAATTGGTTCACAACCAAACACAAATTTAGCAG
AAAAGGCAGCACTTGAAATCGATCAGAAACTCGGTGGCTTTCTTGTCAATGCAGAACTAG
AAGCAAGATCAAATCTTTATGTAGCTGGAGATGTAGCATGTTTTTATGATCCTCATTTGG
GTCGAAGGAGAGTAGAACATCATGATCATGCTGTTGTATCAGGAAGACTTGCTGGTGAAA
ATATGGTTGGTCTAAGAAAACCATACAAACATCAGTCAATGTTCTGGTCAGATTTAGGCA
CAGCTATTGGATATGAGGCAATTGGACTAATAGATTCATCTTTAGAAACTGTAGGAATTT
TTGCACAAACTAATTCCAATGATAATAAAAATGAAATTAAGATTGATGGTGAAAACAAAG
AAGCACATTCAGTCGAAAGCGGCAACTTTAAAAAAGAAAACGGAACTGATAACAAATCTG
AAAGCTATAACAAGGGTATTTTATTTTATATGAAAAATGACAGAATTGTTGGAATTCTTC
TATGGAATGTGTTCAACCGTATTTCAATTGCAAGAAAAATTTTATCGAGTGAAGAAAAAT
TTGATGATTTGAATGAAGTTGCCAAGCTCTTTGACATTTTTGAACAACATCATCAACAAG
ATAAAGAAGATTTAGAAAAAGAAAAGGGGCAATTAAAGTAA
>g10206.t8 Gene=g10206 Length=282
MAKVLPKYLSEWATERIRDVGVNVLPNSQIVNVELFNGNQIKLILNNGNSIIADFVIQAI
GSQPNTNLAEKAALEIDQKLGGFLVNAELEARSNLYVAGDVACFYDPHLGRRRVEHHDHA
VVSGRLAGENMVGLRKPYKHQSMFWSDLGTAIGYEAIGLIDSSLETVGIFAQTNSNDNKN
EIKIDGENKEAHSVESGNFKKENGTDNKSESYNKGILFYMKNDRIVGILLWNVFNRISIA
RKILSSEEKFDDLNEVAKLFDIFEQHHQQDKEDLEKEKGQLK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g10206.t8 | Coils | Coil | Coil | 271 | 282 | - |
| 9 | g10206.t8 | Gene3D | G3DSA:3.50.50.60 | - | 2 | 138 | 2.4E-37 |
| 10 | g10206.t8 | Gene3D | G3DSA:3.30.390.30 | - | 143 | 269 | 3.2E-43 |
| 8 | g10206.t8 | MobiDBLite | mobidb-lite | consensus disorder prediction | 186 | 206 | - |
| 3 | g10206.t8 | PANTHER | PTHR43557 | APOPTOSIS-INDUCING FACTOR 1 | 1 | 262 | 7.4E-79 |
| 4 | g10206.t8 | PANTHER | PTHR43557:SF4 | APOPTOSIS-INDUCING FACTOR 1, MITOCHONDRIAL | 1 | 262 | 7.4E-79 |
| 1 | g10206.t8 | Pfam | PF07992 | Pyridine nucleotide-disulphide oxidoreductase | 4 | 122 | 1.3E-15 |
| 2 | g10206.t8 | Pfam | PF14721 | Apoptosis-inducing factor, mitochondrion-associated, C-term | 127 | 245 | 2.4E-46 |
| 7 | g10206.t8 | SMART | SM01353 | AIF_C_2 | 127 | 247 | 1.3E-59 |
| 6 | g10206.t8 | SUPERFAMILY | SSF51905 | FAD/NAD(P)-binding domain | 7 | 147 | 1.45E-19 |
| 5 | g10206.t8 | SUPERFAMILY | SSF55424 | FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 140 | 260 | 7.69E-39 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0050660 | flavin adenine dinucleotide binding | MF |
| GO:0055114 | NA | NA |
| GO:0046983 | protein dimerization activity | MF |
| GO:0016491 | oxidoreductase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
