General information for g10209.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Transmembrane GTPase Marf.
Parent gene
- The parent gene g10209 is located on chr_1: 8221858..8222309 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10209 | g10209.t4 | isoform | g10209.t4 | 8220339 | 8222309 |
| chr_1 | g10209 | g10209.t4 | exon | g10209.t4.exon1 | 8220339 | 8220914 |
| chr_1 | g10209 | g10209.t4 | cds | g10209.t4.CDS1 | 8220384 | 8220914 |
| chr_1 | g10209 | g10209.t4 | exon | g10209.t4.exon2 | 8221623 | 8222043 |
| chr_1 | g10209 | g10209.t4 | cds | g10209.t4.CDS2 | 8221623 | 8221886 |
| chr_1 | g10209 | g10209.t4 | exon | g10209.t4.exon3 | 8222108 | 8222309 |
| chr_1 | g10209 | g10209.t4 | TTS | g10209.t4 | 8222554 | 8222554 |
| chr_1 | g10209 | g10209.t4 | TSS | g10209.t4 | NA | NA |
Sequences
>g10209.t4 Gene=g10209 Length=1199
AAGAAGTTACTTACAGACAGAATAAGTGCAACTGAGACACAATTAATGGTTGTTACACGA
GAAATGAAAATGAAAATACATAATATGGTTGAAGAAGTTGAGCAAAAAGTTTCAAAAGCA
TTGAATGAAGAAATTTGGCGATTGAATGTACTTGTTGACGAGTTTAATCTTCCTTTTCAT
ACTGATGCATTGGTTCTCAATGTATATAAGAAAGAAATGAATGGATATGTTGAAAGTGGT
CTTGGTTCTAATTTAAGGGCTCGTTTGTCAACTGCACTTGCAATGAATATTGAGACAGCA
CAACGAGAAATGACTGATAGAATGACAGCTCTTGTACCAAAGGAGAAGCTTAAGGATCAA
ACCAATCAAATTATTACTGCAAGAAACCAGCCTTTTGAAATGTTATATTCACTTAACTGT
CAAAATTTATGCAGTGATTTTCAAGAAGATTTAGAGTTTAGATTTTCTTGGGGAATTACA
GCTCTCATACAGCGTTTCAATGCAAAAAAGGCTGCATCGAAAACAGGAAAATCTGGAGTG
GTAGCAAATCAATATCGTAATAATGGAAATTTGAACTCGACACAAGCTGTTACACCAAGT
GCTGATTTGAATTCACCAATATCATTACTGCCACAATTTAATGGTGAATTTACAACTGAA
GAACAACTATCACTTGTTTCGAGAATTGCAGCTGCTTCAATTGGTTCACAGGGAACAGTT
GGTGGATTAGTTATTGCTGGAATTGTAAATATAATATATATAGCAATAATTTTAATTTTA
TTTAATATAATCATTTTTAGTTGTTTAAAACTATTGGATGGAGAGTGCTGTTTGCTGTAG
GCGGTATATACTTTTCAGTTTATGCTTATGAGCGTTTATCATGGACTAATAAAGCCAAAG
AAAGGAAATTCAAGGAACAATATGTAAAGCATGCAACAAGAAAGTTGAAATTGATAGTTG
ATTTGACATCTGCTAATTGTAGTCATCAAGTTCAACAGGAGTTATCTAGTACTTTTGCTA
GACTTTGTCGTGTTGTTGATTGTAGTCAAAGTGAAATGAATAATGAATTAAAGGATATCG
AAGCATCACTTAATGTTCTCGAAGCAAATCAAAAACAAATAAAACTATTGAGGAATAAAG
CTTCTTTCATTACTAATAAATTAGATACGTTCGAAAATAATTATATAAAATCTAACTAA
>g10209.t4 Gene=g10209 Length=264
MVVTREMKMKIHNMVEEVEQKVSKALNEEIWRLNVLVDEFNLPFHTDALVLNVYKKEMNG
YVESGLGSNLRARLSTALAMNIETAQREMTDRMTALVPKEKLKDQTNQIITARNQPFEML
YSLNCQNLCSDFQEDLEFRFSWGITALIQRFNAKKAASKTGKSGVVANQYRNNGNLNSTQ
AVTPSADLNSPISLLPQFNGEFTTEEQLSLVSRIAAASIGSQGTVGGLVIAGIVNIIYIA
IILILFNIIIFSCLKLLDGECCLL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 4 | g10209.t4 | Coils | Coil | Coil | 8 | 28 | - |
| 1 | g10209.t4 | PANTHER | PTHR10465:SF1 | MITOFUSIN-2 | 3 | 235 | 1.1E-40 |
| 2 | g10209.t4 | PANTHER | PTHR10465 | TRANSMEMBRANE GTPASE FZO1 | 3 | 235 | 1.1E-40 |
| 5 | g10209.t4 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 227 | - |
| 7 | g10209.t4 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 228 | 250 | - |
| 6 | g10209.t4 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 251 | 264 | - |
| 3 | g10209.t4 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 228 | 250 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0048662 | negative regulation of smooth muscle cell proliferation | BP |
| GO:0008053 | mitochondrial fusion | BP |
| GO:0016021 | integral component of membrane | CC |
| GO:0005739 | mitochondrion | CC |
| GO:0003924 | GTPase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
