General information for g10282.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Membrane-bound transcription factor site-1 protease.
Parent gene
- The parent gene g10282 is located on chr_1: 8625106..8625937 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10282 | g10282.t1 | TSS | g10282.t1 | 8622477 | 8622477 |
| chr_1 | g10282 | g10282.t1 | isoform | g10282.t1 | 8622660 | 8625937 |
| chr_1 | g10282 | g10282.t1 | exon | g10282.t1.exon1 | 8622660 | 8622920 |
| chr_1 | g10282 | g10282.t1 | cds | g10282.t1.CDS1 | 8622660 | 8622920 |
| chr_1 | g10282 | g10282.t1 | exon | g10282.t1.exon2 | 8622983 | 8623502 |
| chr_1 | g10282 | g10282.t1 | cds | g10282.t1.CDS2 | 8622983 | 8623502 |
| chr_1 | g10282 | g10282.t1 | exon | g10282.t1.exon3 | 8623563 | 8625689 |
| chr_1 | g10282 | g10282.t1 | cds | g10282.t1.CDS3 | 8623563 | 8625689 |
| chr_1 | g10282 | g10282.t1 | exon | g10282.t1.exon4 | 8625750 | 8625937 |
| chr_1 | g10282 | g10282.t1 | cds | g10282.t1.CDS4 | 8625750 | 8625937 |
| chr_1 | g10282 | g10282.t1 | TTS | g10282.t1 | 8626218 | 8626218 |
Sequences
>g10282.t1 Gene=g10282 Length=3096
ATGATGAAAAAGAGAAAAGATTTCGTAATTTTCTTTATCTTCGTAATAATTAATTTATTC
AATTGTAATACGACATTGGAAAATGAGAAAGATATTCAAGATGAAGGATTAAAATGCTGC
GAGAATGCAACAGATCAACGTTTAATTGTTGAATTTTCATCAAGTATTGTAGAACATGAA
TACATAATACACTTTAATAATTATTATAAGAAAGAAACACGAAGGAAATACATCATTTTA
GCTCTTGATAATAATTCCGAGATCAAAAATTTTACAATTGTTGAAAGACAAAATCCAGCA
AGCGACTACCCAAGTGACTTTGACGTTATTCATCTCTATGAAAAAACTCCACTAAAAGGA
CTTGATTTGCTTATTAAACATCCTCTTATAAAAAGTGTTAGTCCACAACGAATAGTACAT
AGAACGCTAAAATTTCTAAATAAAGATGATGAACAAGAAGAAGAAATAGTAGCAAATAAT
GAAAATGATGGTGATACAAACAAGGTGAATGATAATGAAGATGATATTATCAATTATATT
TCAAAGCATCTTAAACTTGATACGAGAACTGCCAATTTAAAAAATAAGCAAGGAGAATGT
TGTGTGGCTGAATTTCAAAATTTTAGACGAGGTCTATCATCATCAACTTCAATTGATACC
AGTCAACAGCAGCAGCAACAGTTACCGATAGAAAATAATGTGAATTCTCACTCTAATCGA
CGTTTATTAAGAGCAATTCCTAGGCAAATAACATCAATTTTGAAAGCAGACGCATTATGG
AGCATCGGCATCACTGGCAAAGGAGTGAAAGTTGCTGTTTTCGACACAGGTTTAAGTAAA
TCACATCCACATTTTAAGAAAATCAAAGAGAGGACTAATTGGACAAATGAAAAATCATTG
AGTGATGGGATCTCTCATGGAACTTTTGTCACAGGCATTATCGGTTCTTCAAAAGAATGT
TTAGGATTTGCACCAGATGCTGACATTCATATATATCGTGTATTTACAAGTAATCAAGTG
AGCTACACTTCTTGGTTTCTCGATGCATTCAATTATGCAATACTTAAAAAAATCAATGTC
ATTAATTTGAGCATTGGTGGTCCTGATTTTTTGGATCGTCCATTTGTTGATAAAGTACTT
GAGTTATCAGCAAATAAAGTTATAATGGTATCAGCAATAGGCAATGATGGACCATTATAT
GGAACTCTAAATAATCCCGGTGATCAAATGGATGTTATTGGTGTTGGAGGTATGAATTTT
GAAGAAAAGATTGCTAAATTTTCCTCACGCGGTATGACAACATGGGAACTACCAGAAGGC
TATGGACGATTAAAACCTGACATTGTCACATACGGATCTCAAGTGAAAGGTTCAAATTTA
AAAGGTGGCTGTAGATCACTTTCGGGAACAAGCGTTGCATCACCAGTCGTAGCAGGAGCA
GTCACTCTTATCATATCAGGTGTATTGAAAAAAATGGATTATATTAATCCATCGTCGGTA
AAGCAGGCTCTCATTGAAGGTGCAACACGATTAAATGACAATAATATGTTTGAACAAGGC
CATGGCAAATTAAATGTTCTCAAATCAATTAAAATTTTATCAGAATATCAACCTAAGATA
ACTTTGTCTCCAACTAATTTAGATATGACCGACGATTACATGTTTCCCTACAGTTCGCAA
CCTATTTATTACACAATGCAACCAATAATTGTAAATGTTACTATTTTAAATGGCATATCA
GTTACTGGTCGTGTTGCTGAAGTTCAATGGTATCCATATCAAAATGAAAATGGAAATTTA
TTAAATGTGTCAATTGGATATTCAGAAATTTTATGGCCTTGGTCTGGATGGATGAGTTTG
CATATCGTTGTCAATGAATACGGACAATATTTTGAAGGTGATGCACAAGGGCATGTTGCA
ATTACAATTGAGACTCCTTCAGCTGATGATCCTAGTGAGAAATTAAATTCAACAGTTAAC
TTTTCCATTCGATGTCGAATTATTCCTAAACCACCGAGACAAAAGAGAATTTTATGGGAT
CAATATCATAATCTTCGATATCCGCCAGGTTATCTACCAAGAGATTCTTTAAAAGTAAAA
CAAGACCCACTTGATTGGCGTTCAGATCATATTCATACAAATTTCAAAGATATGTACACA
CATTTAAGATCATCTGGTTATTATGTTGAAGTTTTAGGTCAACCTTTTACTTGTTTTAAC
GCAAGTCACTATGGAACTCTTTTGCTTGTTGACCCAGAAGAAGAGTTTTTCGATGCAGAA
ATTGAAAAATTATATGATGATGTTACTAATAAAAATTTGAGTCTTATTGTTTTTGCTGAC
TGGTACAATACAACTGTAATGAAACATATGAAATTTTATGATCAAAATACACGTCAATGG
TGGGTTCCTGATACTGGTGGTTGTAATGTTCCTGCACTCAATGAATTGTTAAATTCATTC
GGAATAGAATTTGGTGATAAAGTTTTAGAAGGATATTTTACTATGGGCGATCATCATGAC
ATGTATTATGCAAGTGGTACAAGTATCGTTAAATTTCCAAAAGCAAATCAATCAGTTTTG
ATTGAAAGAGATTTAGTTGATCAAGGATCTGAAATTTTGAAACTTCCACAAAATGGTAGT
CATCAAAAAGACCTTCCAGAAATTGATTTAAAGAATGTTCGAGTGAAACACAAAGAGGTT
ATTTTGGGAATGCAACAAACAGTGTCAACTTTAAGTTCAAGAAAGGGAGGAAGAATAGCA
GCTTATGGAGATAGTAATTGTTTAGATTCTACTCATATGGAAAAAGCATGTTTCTGGCTT
TTAGATGCACTTTTGGAATATTCAATGACGAGTCATGTAAGTGGATTATTAAAGAGTATG
AATCGAATGCAAAATATTGAGTTTACGGAGAAAACAAAGCCGCAGAGATTACTCCATAAT
AATTTACACCTGTATTCTAAAATTCTTGATTCTAATGATCGTGATACCAAACGACCACTT
CAAAAATGCCGAAAATTCAATTGGGAGTTTCCATATTTTCTAAATATAACGAGATCATTT
ATTAATGAAGATCCTATCATAACTAACAACATCTAA
>g10282.t1 Gene=g10282 Length=1031
MMKKRKDFVIFFIFVIINLFNCNTTLENEKDIQDEGLKCCENATDQRLIVEFSSSIVEHE
YIIHFNNYYKKETRRKYIILALDNNSEIKNFTIVERQNPASDYPSDFDVIHLYEKTPLKG
LDLLIKHPLIKSVSPQRIVHRTLKFLNKDDEQEEEIVANNENDGDTNKVNDNEDDIINYI
SKHLKLDTRTANLKNKQGECCVAEFQNFRRGLSSSTSIDTSQQQQQQLPIENNVNSHSNR
RLLRAIPRQITSILKADALWSIGITGKGVKVAVFDTGLSKSHPHFKKIKERTNWTNEKSL
SDGISHGTFVTGIIGSSKECLGFAPDADIHIYRVFTSNQVSYTSWFLDAFNYAILKKINV
INLSIGGPDFLDRPFVDKVLELSANKVIMVSAIGNDGPLYGTLNNPGDQMDVIGVGGMNF
EEKIAKFSSRGMTTWELPEGYGRLKPDIVTYGSQVKGSNLKGGCRSLSGTSVASPVVAGA
VTLIISGVLKKMDYINPSSVKQALIEGATRLNDNNMFEQGHGKLNVLKSIKILSEYQPKI
TLSPTNLDMTDDYMFPYSSQPIYYTMQPIIVNVTILNGISVTGRVAEVQWYPYQNENGNL
LNVSIGYSEILWPWSGWMSLHIVVNEYGQYFEGDAQGHVAITIETPSADDPSEKLNSTVN
FSIRCRIIPKPPRQKRILWDQYHNLRYPPGYLPRDSLKVKQDPLDWRSDHIHTNFKDMYT
HLRSSGYYVEVLGQPFTCFNASHYGTLLLVDPEEEFFDAEIEKLYDDVTNKNLSLIVFAD
WYNTTVMKHMKFYDQNTRQWWVPDTGGCNVPALNELLNSFGIEFGDKVLEGYFTMGDHHD
MYYASGTSIVKFPKANQSVLIERDLVDQGSEILKLPQNGSHQKDLPEIDLKNVRVKHKEV
ILGMQQTVSTLSSRKGGRIAAYGDSNCLDSTHMEKACFWLLDALLEYSMTSHVSGLLKSM
NRMQNIEFTEKTKPQRLLHNNLHLYSKILDSNDRDTKRPLQKCRKFNWEFPYFLNITRSF
INEDPIITNNI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 15 | g10282.t1 | CDD | cd07479 | Peptidases_S8_SKI-1_like | 260 | 511 | 1.3588E-177 |
| 9 | g10282.t1 | Gene3D | G3DSA:3.40.50.200 | - | 259 | 540 | 6.7E-67 |
| 2 | g10282.t1 | PANTHER | PTHR43806:SF7 | MEMBRANE-BOUND TRANSCRIPTION FACTOR SITE-1 PROTEASE | 56 | 936 | 0.0 |
| 3 | g10282.t1 | PANTHER | PTHR43806 | PEPTIDASE S8 | 56 | 936 | 0.0 |
| 6 | g10282.t1 | PRINTS | PR00723 | Subtilisin serine protease family (S8) signature | 266 | 285 | 4.2E-15 |
| 5 | g10282.t1 | PRINTS | PR00723 | Subtilisin serine protease family (S8) signature | 302 | 315 | 4.2E-15 |
| 4 | g10282.t1 | PRINTS | PR00723 | Subtilisin serine protease family (S8) signature | 468 | 484 | 4.2E-15 |
| 1 | g10282.t1 | Pfam | PF00082 | Subtilase family | 266 | 522 | 3.2E-43 |
| 11 | g10282.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 22 | - |
| 12 | g10282.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 7 | - |
| 13 | g10282.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 8 | 17 | - |
| 14 | g10282.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 18 | 22 | - |
| 10 | g10282.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 23 | 1031 | - |
| 16 | g10282.t1 | ProSitePatterns | PS00137 | Serine proteases, subtilase family, histidine active site. | 306 | 316 | - |
| 17 | g10282.t1 | ProSitePatterns | PS00138 | Serine proteases, subtilase family, serine active site. | 469 | 479 | - |
| 18 | g10282.t1 | ProSiteProfiles | PS51892 | Serine proteases, subtilase domain profile. | 247 | 530 | 32.031 |
| 7 | g10282.t1 | SUPERFAMILY | SSF52743 | Subtilisin-like | 48 | 629 | 6.33E-66 |
| 8 | g10282.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 22 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004252 | serine-type endopeptidase activity | MF |
| GO:0006508 | proteolysis | BP |
| GO:0008236 | serine-type peptidase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K08653 (membrane-bound transcription factor site-1 protease)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
