General information for g10286.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Uridine-cytidine kinase.
Parent gene
- The parent gene g10286 is located on chr_1: 8652184..8652916 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10286 | g10286.t1 | TTS | g10286.t1 | 8647558 | 8647558 |
| chr_1 | g10286 | g10286.t1 | isoform | g10286.t1 | 8648212 | 8652352 |
| chr_1 | g10286 | g10286.t1 | exon | g10286.t1.exon1 | 8648212 | 8648420 |
| chr_1 | g10286 | g10286.t1 | cds | g10286.t1.CDS1 | 8648212 | 8648420 |
| chr_1 | g10286 | g10286.t1 | exon | g10286.t1.exon2 | 8650218 | 8650248 |
| chr_1 | g10286 | g10286.t1 | cds | g10286.t1.CDS2 | 8650218 | 8650248 |
| chr_1 | g10286 | g10286.t1 | exon | g10286.t1.exon3 | 8651489 | 8651618 |
| chr_1 | g10286 | g10286.t1 | cds | g10286.t1.CDS3 | 8651489 | 8651618 |
| chr_1 | g10286 | g10286.t1 | exon | g10286.t1.exon4 | 8651678 | 8651686 |
| chr_1 | g10286 | g10286.t1 | cds | g10286.t1.CDS4 | 8651678 | 8651686 |
| chr_1 | g10286 | g10286.t1 | exon | g10286.t1.exon5 | 8651757 | 8652162 |
| chr_1 | g10286 | g10286.t1 | cds | g10286.t1.CDS5 | 8651757 | 8652162 |
| chr_1 | g10286 | g10286.t1 | exon | g10286.t1.exon6 | 8652319 | 8652352 |
| chr_1 | g10286 | g10286.t1 | cds | g10286.t1.CDS6 | 8652319 | 8652352 |
| chr_1 | g10286 | g10286.t1 | TSS | g10286.t1 | 8652415 | 8652415 |
Sequences
>g10286.t1 Gene=g10286 Length=819
ATGGAAATTGAACCTAAAAAACCTTTCCTAATAGGAGTTGCAGGAGGTACCGCAAGTGGC
AAAAGTTCAGTATGTAAGCGAATTATTGAAAAATTGGGACAAGCTGACATAAATGAACGA
CAACGTCAAGTAGTAAGCATTAGCCAGGATTCCTTTTATCGTGAACTTACAGAAGAAGAG
AAAATTAAGGCGCAAAAGGGGCAGTTTAATTTTGATCATCCTCAATCTTTTGACGAAGAG
TTAATGTACACAACAATGAAGCAAATTTTATCAGGCGAAACAGTTGTATTGCACTCATAT
GATTACAAGACAAACTCTAAATCTACTGAAAAGATTACAATTTATCCAGCTGATGTTGTA
CTTTTTGAAGGAATTTTGGTCTTTTATTTTCCGTCTATTCGCGATCTCTTTCATATGAAG
TTGTTTGTTGATACAGATTCTGATACCAGACTTGCAAGAAGAGTACCTCGTGACATAAAA
GAAAGAGGAAGAGATCTTGATCAGGTTTTAAATCAGTATATGATGTTTGTTAAGCCAGCT
TTTGAAGAGTTTTGTTCACCAACAAAAAAATATGCTGATGTTATTATCCCACGAGGGGTC
GACAATTTGGTTGCTATTGACTTGATTGTTCAACATCTTAGAGACTTTTTGAGTGACCGT
TTATCTGCTGATTCCATGACTCTCTCACCAACAACAACACCGGCATTAAATAACAATGCC
TCGTCATCAGCTACTGCTATGAATGGAGGTTCACGCGGAGGTAAGAACAAGAACATTCAT
TTTAATGGCGATCCAAGTCTAAGAAATAGACCACACTAA
>g10286.t1 Gene=g10286 Length=272
MEIEPKKPFLIGVAGGTASGKSSVCKRIIEKLGQADINERQRQVVSISQDSFYRELTEEE
KIKAQKGQFNFDHPQSFDEELMYTTMKQILSGETVVLHSYDYKTNSKSTEKITIYPADVV
LFEGILVFYFPSIRDLFHMKLFVDTDSDTRLARRVPRDIKERGRDLDQVLNQYMMFVKPA
FEEFCSPTKKYADVIIPRGVDNLVAIDLIVQHLRDFLSDRLSADSMTLSPTTTPALNNNA
SSSATAMNGGSRGGKNKNIHFNGDPSLRNRPH
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g10286.t1 | CDD | cd02023 | UMPK | 10 | 215 | 7.44086E-105 |
| 11 | g10286.t1 | Gene3D | G3DSA:3.40.50.300 | - | 6 | 226 | 8.2E-72 |
| 10 | g10286.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 246 | 272 | - |
| 2 | g10286.t1 | PANTHER | PTHR10285 | URIDINE KINASE | 6 | 220 | 9.4E-104 |
| 3 | g10286.t1 | PANTHER | PTHR10285:SF66 | URIDINE-CYTIDINE KINASE 1 | 6 | 220 | 9.4E-104 |
| 6 | g10286.t1 | PRINTS | PR00988 | Uridine kinase signature | 8 | 25 | 8.4E-24 |
| 5 | g10286.t1 | PRINTS | PR00988 | Uridine kinase signature | 92 | 107 | 8.4E-24 |
| 4 | g10286.t1 | PRINTS | PR00988 | Uridine kinase signature | 148 | 158 | 8.4E-24 |
| 8 | g10286.t1 | PRINTS | PR00988 | Uridine kinase signature | 162 | 173 | 8.4E-24 |
| 7 | g10286.t1 | PRINTS | PR00988 | Uridine kinase signature | 184 | 197 | 8.4E-24 |
| 1 | g10286.t1 | Pfam | PF00485 | Phosphoribulokinase / Uridine kinase family | 10 | 204 | 3.4E-46 |
| 9 | g10286.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 4 | 209 | 4.29E-41 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0019206 | nucleoside kinase activity | MF |
| GO:0016301 | kinase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K00876 (uridine kinase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
