General information for g10334.t22
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Protein disulfide-isomerase A3.
Parent gene
- The parent gene g10334 is located on chr_1: 8934649..8935590 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10334 | g10334.t22 | TTS | g10334.t22 | 8933125 | 8933125 |
| chr_1 | g10334 | g10334.t22 | isoform | g10334.t22 | 8933413 | 8935590 |
| chr_1 | g10334 | g10334.t22 | exon | g10334.t22.exon1 | 8933413 | 8933710 |
| chr_1 | g10334 | g10334.t22 | exon | g10334.t22.exon2 | 8933766 | 8934407 |
| chr_1 | g10334 | g10334.t22 | cds | g10334.t22.CDS1 | 8933996 | 8934407 |
| chr_1 | g10334 | g10334.t22 | exon | g10334.t22.exon3 | 8934468 | 8934696 |
| chr_1 | g10334 | g10334.t22 | cds | g10334.t22.CDS2 | 8934468 | 8934696 |
| chr_1 | g10334 | g10334.t22 | exon | g10334.t22.exon4 | 8934759 | 8934836 |
| chr_1 | g10334 | g10334.t22 | cds | g10334.t22.CDS3 | 8934759 | 8934836 |
| chr_1 | g10334 | g10334.t22 | exon | g10334.t22.exon5 | 8934917 | 8934967 |
| chr_1 | g10334 | g10334.t22 | cds | g10334.t22.CDS4 | 8934917 | 8934967 |
| chr_1 | g10334 | g10334.t22 | exon | g10334.t22.exon6 | 8935028 | 8935088 |
| chr_1 | g10334 | g10334.t22 | cds | g10334.t22.CDS5 | 8935028 | 8935055 |
| chr_1 | g10334 | g10334.t22 | exon | g10334.t22.exon7 | 8935429 | 8935590 |
| chr_1 | g10334 | g10334.t22 | TSS | g10334.t22 | 8935652 | 8935652 |
Sequences
>g10334.t22 Gene=g10334 Length=1521
ATGAAATTACTTGTTTTTCTGTCATTTTTGTTTGTTGCTGAGTTGGCTCTCTCGGCTGAG
AGTGATGTTCTTGAATTGACTGATTCTGATTTTGAAACTACAATCAAAGAATATCCAACA
GTGTTGGCAATGGTAATATAAAATAATAATTACAATAATATACTTAAACCAGAATATGCC
AAAGCAGCAGAATTGATGAGAACTGATGATCCTCCAATTACTCTTGTCAAAGTTGATTGT
ACAGAAGGCGGCAAGGATACTTGCAGCAAATTCGGTGTTTCTGGATATCCCACTCTCAAA
ATTTTCAGAAACGGTGAAAATCCTCAGGATTATAATGGTCCACGTGAAGCAAGTGGTATT
GTGAAATATATGAGAGCACAAGTTGGTCCATCATCAAAGGATCTTCTAACAGTTGAAGCA
TATGAAAAGTTCTTGGGTGTTCAAGAGGGTGCCGTAGTTGGATTCTTTGAAAAAGAAACG
GATTTGAAGACTGTTTTCTTAAAATATGCCGATTTGCAACGTGAGAAACTTCGCTTTGCA
CATTCAAGTGATCCAGAAATTCTCAAGAAAGTTGGCGAAACAAACGCTATTCTTCTTTAT
CGTGCACCACAATTGAGTAATAAGTTTGAACCATCTTTTGTTAAATTCACTGGAAAAGAT
TCAAGTGATCTTAAAGAATTTGTTAAGAAGAACTTCCACGGTTTAGTTGGTGTACGTAGT
CGTGATACTATTACTGATTTCAACAATCCATTGGTAACTGCATATTATGCTGTTGATTAT
ATTAAAAATGCAAAAGGCACAAACTACTGGCGCAATCGTGTACTTAAAGTTGCCAAAGAA
TGGGAAGGTAAAATCAATTTTGCTATTGCTGCTAAAGATGAATTCCAACATGAATTGAAT
GAATATGGTTACGATTATGTCGGTGATAAACCAATAATTTTGGCTCGTGACGCTCAAAAT
CAAAAGTTCATCATGAAAGATGAGTTTTCGTAAGTTTTTTTTTCAATAGTTATACACACG
TATCTGATATCTTCTTTTTCTTATAGTGTTGACAATCTTCAAGCATTTGTCAATGATCTT
TATGAAGGCAATCTGGAGCCTTACGTTAAATCAGAAGCAATTCCAGTCGATCAAGATGGC
CCAGTTACAGTTGTAGTTGCAAAGAACTTTAATGAGGCTGTTCCAAAAGATAAGGATGTT
TTAATCGAATTCTACGCACCATGGTGTGGTCATTGCAAAAAATTAGCTCCAACATTCGAT
GAATTAGGAACAAAATTGAAGGGTGAAGATGTTGTTATTGCCAAAATGGATGCTACTGCA
AACGATGTTCCTCCTCAATTTGATGTTCGCGGATTCCCGACACTCTTCTGGTTGCCTAAG
GGCGCTCATGATAAACCAGTTAGATACGATGGCGGTCGTGAATTGAACGATTTTATCAGC
TACATCAGTAAACACGCTACAAATGAATTAAAAGGATACGATCGCTCTGGAAACGAAAAG
AAACAAAAGACAGAATTGTAA
>g10334.t22 Gene=g10334 Length=265
MRTDDPPITLVKVDCTEGGKDTCSKFGVSGYPTLKIFRNGENPQDYNGPREASGIVKYMR
AQVGPSSKDLLTVEAYEKFLGVQEGAVVGFFEKETDLKTVFLKYADLQREKLRFAHSSDP
EILKKVGETNAILLYRAPQLSNKFEPSFVKFTGKDSSDLKEFVKKNFHGLVGVRSRDTIT
DFNNPLVTAYYAVDYIKNAKGTNYWRNRVLKVAKEWEGKINFAIAAKDEFQHELNEYGYD
YVGDKPIILARDAQNQKFIMKDEFS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g10334.t22 | CDD | cd02961 | PDI_a_family | 4 | 59 | 6.52341E-17 |
| 12 | g10334.t22 | CDD | cd03073 | PDI_b’_ERp72_ERp57 | 171 | 265 | 5.74285E-36 |
| 11 | g10334.t22 | Coils | Coil | Coil | 257 | 265 | - |
| 10 | g10334.t22 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 1 | 63 | 1.2E-16 |
| 9 | g10334.t22 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 64 | 173 | 8.6E-31 |
| 8 | g10334.t22 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 175 | 265 | 6.0E-30 |
| 3 | g10334.t22 | PANTHER | PTHR18929:SF60 | PROTEIN DISULFIDE-ISOMERASE | 8 | 265 | 1.2E-68 |
| 4 | g10334.t22 | PANTHER | PTHR18929 | PROTEIN DISULFIDE ISOMERASE | 8 | 265 | 1.2E-68 |
| 2 | g10334.t22 | Pfam | PF00085 | Thioredoxin | 7 | 60 | 4.7E-11 |
| 1 | g10334.t22 | Pfam | PF13848 | Thioredoxin-like domain | 92 | 265 | 1.2E-28 |
| 7 | g10334.t22 | SUPERFAMILY | SSF52833 | Thioredoxin-like | 4 | 64 | 7.36E-14 |
| 6 | g10334.t22 | SUPERFAMILY | SSF52833 | Thioredoxin-like | 68 | 167 | 1.89E-12 |
| 5 | g10334.t22 | SUPERFAMILY | SSF52833 | Thioredoxin-like | 169 | 260 | 2.75E-5 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed