General information for g10380.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as 26S proteasome non-ATPase regulatory subunit 1.
Parent gene
- The parent gene g10380 is located on chr_1: 9331680..9338812 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10380 | g10380.t1 | TSS | g10380.t1 | 9330401 | 9330401 |
| chr_1 | g10380 | g10380.t1 | isoform | g10380.t1 | 9330528 | 9338812 |
| chr_1 | g10380 | g10380.t1 | exon | g10380.t1.exon1 | 9330528 | 9330552 |
| chr_1 | g10380 | g10380.t1 | cds | g10380.t1.CDS1 | 9330528 | 9330552 |
| chr_1 | g10380 | g10380.t1 | exon | g10380.t1.exon2 | 9330649 | 9330766 |
| chr_1 | g10380 | g10380.t1 | cds | g10380.t1.CDS2 | 9330649 | 9330766 |
| chr_1 | g10380 | g10380.t1 | exon | g10380.t1.exon3 | 9330839 | 9332318 |
| chr_1 | g10380 | g10380.t1 | cds | g10380.t1.CDS3 | 9330839 | 9332318 |
| chr_1 | g10380 | g10380.t1 | exon | g10380.t1.exon4 | 9337803 | 9337818 |
| chr_1 | g10380 | g10380.t1 | cds | g10380.t1.CDS4 | 9337803 | 9337818 |
| chr_1 | g10380 | g10380.t1 | exon | g10380.t1.exon5 | 9338207 | 9338406 |
| chr_1 | g10380 | g10380.t1 | cds | g10380.t1.CDS5 | 9338207 | 9338406 |
| chr_1 | g10380 | g10380.t1 | exon | g10380.t1.exon6 | 9338744 | 9338812 |
| chr_1 | g10380 | g10380.t1 | cds | g10380.t1.CDS6 | 9338744 | 9338812 |
| chr_1 | g10380 | g10380.t1 | TTS | g10380.t1 | NA | NA |
Sequences
>g10380.t1 Gene=g10380 Length=1908
ATGATTATGAATATAACATCAGCAGCCGGAATTATATCCTTGCTCGACGAGCCAATGCCA
GAGCTTAAGATTTTTGCTCTAAAGAAACTTGATAATATCGTTGATGAATTTTGGCCGGAA
ATTTCAGAAGCTGTCGAAAAACTTGAAATTCTTCATGAAGATAAACAGTTTTCTCAACAT
GAGTTGGCAGCATTAGTTGCATCAAAGGTTTATTATCATCTTGGTGCATTCGAAGATTCT
TTGACTTATGCATTAGGAGCCGGAAATCTTTTCGATGTGAATGCTCGAAATGAGTACGTC
GATACAATCATTGCAAAGTGTATCGATTTTTATACGCAACAACGAGTTGCTATTTTTGAG
AATTCAAAGAATGAAAAACCGATTGATCCACGATTGGAAGCTATTGTGAACCGTATGATT
CAGCGTTGTCTTGATGATGGTCAATATCGTCAAGCTCTCGGTATTGCTCTTGAAACACGT
CGTATGGATATTGTAGAAGCATCGATAATGAAATCTGATGATGTTTCTGGTATGCTTGCT
TATGCATTTCAAGTTACAATGAGTCTAATTCAAAATCGAGGATTTCGCAATACTGTGTTA
CGCTGCCTTGTTAGCCTCTATCGAAATCTTGGGATTCTTGATTATGTCAATATGGTTCAA
TGTCTCATATTTTTGGAGGATCCAATGGAAGTTGCACAACTGTTAGATAATCTTACAAAA
GGCGGAGACCAGCTTGTGTTGATGGCATATCAAATAGCATTTGATTTATACGAGTCAGCG
ACTCAAGATTTTTTGGGACAAGTTTTACAAGCACTGAAAGCGACTGCTCCTATTCCATCT
GCTCTCGTATCGAATTTGAAACCGCAGGGCGTAAAAGAACCATCAAAGGACGATAAATCA
TCAAAGTCTGATGCAGATGTGGAAATGACTGGGGCTGTTCGCTCGTTAGAAAGCCTAAAC
GACGCAGAGAAAATTCATCAAAAGAACATTGAAAAGTTGGCAAGCATTCTATCGGGTGAG
GTTTCAATTGACTTGCAATTACAGTTTTTGATTCGAAGCAATCATGCTGATTTGCAAATT
TTGAGAGCAACCAAGGAGTCAGTTCGAGTTTCGATCTGCCACACAGCAACTGTTATTGCA
AACGCTTTTATGCACAGTGGCACAACAAGTGATCAATTTTTGAGAGATAATCTTGAATGG
CTTGCTCGAGCAACAAACTGGGCAAAATTAACAGCAACTGCTAGTTTGGGTGTTATTCAT
CGTGGACACGAAAATGAATCACTTGCTCTTATGCAAAGCTACTTACCAAAAGAGTCAGGA
CCCAGTGGATATTCTGAAGGTGGTGGACTTTATGCTCTTGGATTAATTCATGCAAACCAT
GGAGCAAACATTATTGATTATTTACTTCAGCAATTGAAGGATGCTCAAAATGAAAATGTT
CGACATGGAGGTTGTTTGGGACTTGGTCTTGCCGCAATGGGAACACATCGACAAGACGTT
TACGAGCAACTCAAATTCAATTTATATCAAGATGATGCAGTGACTGGTGAAGCTGCAGGT
ATTGCTATGGGAATGGTGATGCTTGGCTCTAAAAATGCAACTGCTATCGAAGATATGGTT
TCGTATGCACAAGAAACAGGTCATGAGAAAATTTTACGAGGCTTGGCAGTTGGTATTTCC
CTTACAATGTTTAATCGATTAGAAGAAAGTGATGCACTGGTTACAAGCTTAACAAATGAT
AAAGATCCAGTATTAAGACGTAGTGGAATGTATACCATTGCAATGGCATATTGCGGTACT
GGAAATAATCAAGCAATAAGAAAATTACTCCATGTAGCGGTTTCGGACGTAAACGATGAT
GTTCGTAGAGCAGCAGTTACTGGAATTGGATTCTTATTGTTTAGGTGA
>g10380.t1 Gene=g10380 Length=635
MIMNITSAAGIISLLDEPMPELKIFALKKLDNIVDEFWPEISEAVEKLEILHEDKQFSQH
ELAALVASKVYYHLGAFEDSLTYALGAGNLFDVNARNEYVDTIIAKCIDFYTQQRVAIFE
NSKNEKPIDPRLEAIVNRMIQRCLDDGQYRQALGIALETRRMDIVEASIMKSDDVSGMLA
YAFQVTMSLIQNRGFRNTVLRCLVSLYRNLGILDYVNMVQCLIFLEDPMEVAQLLDNLTK
GGDQLVLMAYQIAFDLYESATQDFLGQVLQALKATAPIPSALVSNLKPQGVKEPSKDDKS
SKSDADVEMTGAVRSLESLNDAEKIHQKNIEKLASILSGEVSIDLQLQFLIRSNHADLQI
LRATKESVRVSICHTATVIANAFMHSGTTSDQFLRDNLEWLARATNWAKLTATASLGVIH
RGHENESLALMQSYLPKESGPSGYSEGGGLYALGLIHANHGANIIDYLLQQLKDAQNENV
RHGGCLGLGLAAMGTHRQDVYEQLKFNLYQDDAVTGEAAGIAMGMVMLGSKNATAIEDMV
SYAQETGHEKILRGLAVGISLTMFNRLEESDALVTSLTNDKDPVLRRSGMYTIAMAYCGT
GNNQAIRKLLHVAVSDVNDDVRRAAVTGIGFLLFR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g10380.t1 | Gene3D | G3DSA:1.25.10.10 | - | 355 | 635 | 3.1E-122 |
| 8 | g10380.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 287 | 307 | - |
| 9 | g10380.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 291 | 305 | - |
| 5 | g10380.t1 | PANTHER | PTHR10943:SF2 | 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 1 | 3 | 635 | 9.1E-232 |
| 6 | g10380.t1 | PANTHER | PTHR10943 | 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT | 3 | 635 | 9.1E-232 |
| 1 | g10380.t1 | Pfam | PF01851 | Proteasome/cyclosome repeat | 412 | 443 | 2.7E-4 |
| 4 | g10380.t1 | Pfam | PF01851 | Proteasome/cyclosome repeat | 448 | 479 | 3.4E-7 |
| 2 | g10380.t1 | Pfam | PF01851 | Proteasome/cyclosome repeat | 483 | 515 | 4.1E-5 |
| 3 | g10380.t1 | Pfam | PF01851 | Proteasome/cyclosome repeat | 518 | 550 | 1.4E-4 |
| 7 | g10380.t1 | SUPERFAMILY | SSF48371 | ARM repeat | 12 | 633 | 1.42E-21 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0030234 | enzyme regulator activity | MF |
KEGG
Orthology
- This transcript has been annotated with K03032 (26S proteasome regulatory subunit N2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
