Gene loci information

Transcript annotation

  • This transcript has been annotated as Guanine nucleotide-binding protein subunit beta-1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g10402 g10402.t11 TTS g10402.t11 9561301 9561301
chr_1 g10402 g10402.t11 isoform g10402.t11 9561446 9565889
chr_1 g10402 g10402.t11 exon g10402.t11.exon1 9561446 9561552
chr_1 g10402 g10402.t11 cds g10402.t11.CDS1 9561446 9561552
chr_1 g10402 g10402.t11 exon g10402.t11.exon2 9561621 9561837
chr_1 g10402 g10402.t11 cds g10402.t11.CDS2 9561621 9561837
chr_1 g10402 g10402.t11 exon g10402.t11.exon3 9561900 9562130
chr_1 g10402 g10402.t11 cds g10402.t11.CDS3 9561900 9562130
chr_1 g10402 g10402.t11 exon g10402.t11.exon4 9562205 9562405
chr_1 g10402 g10402.t11 cds g10402.t11.CDS4 9562205 9562405
chr_1 g10402 g10402.t11 exon g10402.t11.exon5 9562753 9562962
chr_1 g10402 g10402.t11 cds g10402.t11.CDS5 9562753 9562962
chr_1 g10402 g10402.t11 exon g10402.t11.exon6 9563100 9563160
chr_1 g10402 g10402.t11 cds g10402.t11.CDS6 9563100 9563108
chr_1 g10402 g10402.t11 exon g10402.t11.exon7 9564967 9565889
chr_1 g10402 g10402.t11 TSS g10402.t11 9565889 9565889

Sequences

>g10402.t11 Gene=g10402 Length=1950
AGTGAAAAAATTCAAAATGGCTGGTTAGATGGACAATGTTAACATCGTAAGAAAAGTGTG
AAATATTGTGAAATAAATTGTATTAGCCTCATTAAAAGTTTGATAAAACTCTAATTAAGA
TAGCCATAATTAAGTTTAAATTAAATTTAAACGCTAAGAGACTCAATGTAGCCAAAAAAT
TGGTCTGTGAAAAATCAAGTTCATGATTCGAAAGACGAAAAGAAAATTTTAGTGAAAGAT
CCAAATAGATAACGGTGGCGAGAGTAAAAATTGTGTTCAATATTAAATTTAAAAAAAGGA
AACAACTATTATTAAAAATTTAAATCCCATTATTTCAACTTAACAAGTGATTTTTGCAAA
GAGATATGATACATAGAATCAAAGAAGAAGGAGAGAAAATAACATAAAAATATTAATTAA
ATATTTTAAATCAAAGTATAGCCAAACCCAATAAAGGATTCTGTTCGCGATACTGCAAAA
TAATTTTAAATTAACTGAATGATTTTATGTGAAATAATTAAACAAGTGCAAAAACAGAAA
AAAAAGTTTTGTTGAAAAATATTGATTTCTCGATGTACTACACAAACCAGTAGCCGAAAG
ATTTTTTACTAGAGATAATTGCAAAAAGAAGTCTATATCTACACATATAACAAAAGTGAA
ATCGGCATTACTAAAGGAAAATTAAATAAAGAAAGAAGACGGAGGCGACAGTTAAAGAGC
AGATAAACCAAAATAGAAAAAAATAAATTCTAAATTAACTAGGCCATTTTTCCATCAAAT
AAATAACGAAAGAAACCTGAAATTCATACGTTAATTAAGAATAATAATAAATATATATTA
CAATCAATCAATCTTTGCATCTCAAGGAATATTAAACATAATATTAAAACTAAAATAATA
AATTCATATTAAAAAAATTCTCGGTGAAAATGAATGAATTGGACGCCTTAAGACAAGAAG
CTGAAACATTAAAAAATGCTATTCGATGCACGGAAAGCAGCATGCGACACCAGCCTCGTG
CAGGCAACGAATAATCTGGAACCAATTGGTCGCATTCAAATGCGTACCAGACGCACATTG
CGTGGTCATTTAGCAAAAATTTATGCTATGCACTGGGGAAGTGATTCGAGAAATTTAGTG
TCAGCATCTCAAGATGGAAAATTGATTGTCTGGGATTCACATACAACAAACAAGGTACAC
GCAATACCTCTACGTAGTTCTTGGGTTATGACATGCGCGTATGCACCATCCGGCAGTTTT
GTTGCATGTGGCGGTTTGGATAATATCTGTTCAATATATAGCTTAAAGACTAGAGAAGGA
AATGTGCGTGTATCACGTGAACTGCCTGGCCATACTGGCTACTTATCTTGTTGTCGATTC
TTGGATGATAATCAGATAGTAACAAGTTCAGGAGATATGTCATGCGGATTATGGGATATA
GAGACGGGCCAGCAATGTACATCGTTTTTGGGACATACTGGTGATGTAATGGCGCTGTCA
TTGTCACCGCATTGTAGAGCGTTCGTTTCAGGAGCTTGCGATGCTTCAGCTAAATTATGG
GACATTCGAGAAGGTCAATGCAAGCAAACCTTCCCTGGTCATGAAAGTGATATTAACGCC
GTAACATTCTTTCCCAATGGCTATGCATTTGCAACTGGTTCAGATGATGCCACTTGCCGT
CTTTTTGATATCCGTGCCGATCAGGAATTGGCAATGTATTCACATGATAACATCATTTGT
GGTATAACATCTGTTGCATTTTCAAAATCTGGACGTCTTTTATTGGCCGGCTATGATGAT
TTCAATTGCAATGTATGGGATACTATGAAAGCTGAACGAGCTGGTATCTTGGCCGGCCAC
GATAACCGCGTATCATGTCTAGGAGTTACAGAAAACGGCATGGCTGTAGCAACAGGGTCG
TGGGATTCATTTTTACGTGTATGGAACTAA

>g10402.t11 Gene=g10402 Length=324
MLFDARKAACDTSLVQATNNLEPIGRIQMRTRRTLRGHLAKIYAMHWGSDSRNLVSASQD
GKLIVWDSHTTNKVHAIPLRSSWVMTCAYAPSGSFVACGGLDNICSIYSLKTREGNVRVS
RELPGHTGYLSCCRFLDDNQIVTSSGDMSCGLWDIETGQQCTSFLGHTGDVMALSLSPHC
RAFVSGACDASAKLWDIREGQCKQTFPGHESDINAVTFFPNGYAFATGSDDATCRLFDIR
ADQELAMYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTMKAERAGILAGHDNRVS
CLGVTENGMAVATGSWDSFLRVWN

Protein features from InterProScan

Transcript Database ID Name Start End E.value
19 g10402.t11 CDD cd00200 WD40 32 324 8.09843E-90
17 g10402.t11 Gene3D G3DSA:2.130.10.10 - 1 324 5.2E-138
7 g10402.t11 PANTHER PTHR19850:SF28 GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-4 4 324 1.2E-199
8 g10402.t11 PANTHER PTHR19850 GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA 4 324 1.2E-199
18 g10402.t11 PIRSF PIRSF002394 GNBP_B 2 324 4.9E-159
14 g10402.t11 PRINTS PR00319 Beta G protein (transducin) signature 35 51 1.3E-32
10 g10402.t11 PRINTS PR00320 G protein beta WD-40 repeat signature 54 68 7.0E-7
13 g10402.t11 PRINTS PR00319 Beta G protein (transducin) signature 54 68 1.3E-32
12 g10402.t11 PRINTS PR00319 Beta G protein (transducin) signature 73 88 1.3E-32
15 g10402.t11 PRINTS PR00319 Beta G protein (transducin) signature 91 108 1.3E-32
11 g10402.t11 PRINTS PR00320 G protein beta WD-40 repeat signature 141 155 7.0E-7
9 g10402.t11 PRINTS PR00320 G protein beta WD-40 repeat signature 183 197 7.0E-7
4 g10402.t11 Pfam PF00400 WD domain, G-beta repeat 32 67 1.6E-4
2 g10402.t11 Pfam PF00400 WD domain, G-beta repeat 120 154 0.0087
5 g10402.t11 Pfam PF00400 WD domain, G-beta repeat 160 196 0.023
3 g10402.t11 Pfam PF00400 WD domain, G-beta repeat 200 238 1.7E-7
1 g10402.t11 Pfam PF00400 WD domain, G-beta repeat 249 282 8.2E-5
6 g10402.t11 Pfam PF00400 WD domain, G-beta repeat 291 324 0.0019
27 g10402.t11 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 54 68 -
28 g10402.t11 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 141 155 -
29 g10402.t11 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 269 283 -
30 g10402.t11 ProSiteProfiles PS50294 Trp-Asp (WD) repeats circular profile. 35 324 56.052
33 g10402.t11 ProSiteProfiles PS50082 Trp-Asp (WD) repeats profile. 35 76 13.783
32 g10402.t11 ProSiteProfiles PS50082 Trp-Asp (WD) repeats profile. 123 163 9.706
31 g10402.t11 ProSiteProfiles PS50082 Trp-Asp (WD) repeats profile. 164 205 14.184
34 g10402.t11 ProSiteProfiles PS50082 Trp-Asp (WD) repeats profile. 206 247 12.848
36 g10402.t11 ProSiteProfiles PS50082 Trp-Asp (WD) repeats profile. 257 291 8.771
35 g10402.t11 ProSiteProfiles PS50082 Trp-Asp (WD) repeats profile. 292 324 14.452
21 g10402.t11 SMART SM00320 WD40_4 28 67 5.5E-7
26 g10402.t11 SMART SM00320 WD40_4 70 109 0.012
25 g10402.t11 SMART SM00320 WD40_4 116 154 8.2E-6
24 g10402.t11 SMART SM00320 WD40_4 157 196 3.5E-6
20 g10402.t11 SMART SM00320 WD40_4 199 238 1.7E-9
23 g10402.t11 SMART SM00320 WD40_4 241 282 9.7E-4
22 g10402.t11 SMART SM00320 WD40_4 285 324 1.1E-4
16 g10402.t11 SUPERFAMILY SSF50978 WD40 repeat-like 11 324 1.47E-76

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0007165 signal transduction BP
GO:0005515 protein binding MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values