General information for g10445.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Acetyl-coenzyme A transporter 1.
Parent gene
- The parent gene g10445 is located on chr_1: 9869178..9871211 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10445 | g10445.t1 | TSS | g10445.t1 | 9869118 | 9869118 |
| chr_1 | g10445 | g10445.t1 | isoform | g10445.t1 | 9869178 | 9871211 |
| chr_1 | g10445 | g10445.t1 | exon | g10445.t1.exon1 | 9869178 | 9869445 |
| chr_1 | g10445 | g10445.t1 | cds | g10445.t1.CDS1 | 9869178 | 9869445 |
| chr_1 | g10445 | g10445.t1 | exon | g10445.t1.exon2 | 9869512 | 9869768 |
| chr_1 | g10445 | g10445.t1 | cds | g10445.t1.CDS2 | 9869512 | 9869768 |
| chr_1 | g10445 | g10445.t1 | exon | g10445.t1.exon3 | 9869832 | 9869855 |
| chr_1 | g10445 | g10445.t1 | cds | g10445.t1.CDS3 | 9869832 | 9869855 |
| chr_1 | g10445 | g10445.t1 | exon | g10445.t1.exon4 | 9869923 | 9869954 |
| chr_1 | g10445 | g10445.t1 | cds | g10445.t1.CDS4 | 9869923 | 9869954 |
| chr_1 | g10445 | g10445.t1 | exon | g10445.t1.exon5 | 9870007 | 9870610 |
| chr_1 | g10445 | g10445.t1 | cds | g10445.t1.CDS5 | 9870007 | 9870610 |
| chr_1 | g10445 | g10445.t1 | exon | g10445.t1.exon6 | 9870668 | 9870713 |
| chr_1 | g10445 | g10445.t1 | cds | g10445.t1.CDS6 | 9870668 | 9870713 |
| chr_1 | g10445 | g10445.t1 | exon | g10445.t1.exon7 | 9870778 | 9871211 |
| chr_1 | g10445 | g10445.t1 | cds | g10445.t1.CDS7 | 9870778 | 9871211 |
| chr_1 | g10445 | g10445.t1 | TTS | g10445.t1 | 9871288 | 9871288 |
Sequences
>g10445.t1 Gene=g10445 Length=1665
ATGAGTGTTGACAATAAGAAAATTGTTAGGCAAGATCAAGAACACCAATTGACTATTAAA
GAAGAAGAAAAAGAGCAGCAAGAAGAAGAAGAGGAAGAAGAATCTGATTTACGAGGAGAT
TATGGAAATGTGGCAATTTTACTGTTTTTATATATATTGCAAGGAATACCTTTAGGGATC
TCTTCAGCTGTTCGCATTCTTCTCACTAATAGGGGTGTATCATATAAAGAACTTGCAATA
TTGTCATTTGCTAGCTACCCATTTACAATGAAGGTTCTTTGGTCTCCAATTGTTGATGCA
ATTTATTTTAAAAAAATTGGTCGAAGAAAGTCCTGGCTTATTCCCGTTCAACTTATGATC
GGAGGATTTATGATTTTTCTAGCACAAAGAGTGAATGATTGGATGGGTGATAGTAAAGGA
CAAGAGCCTCAAATTATTTTTCTCACAATAGTATTCTTTATGCTTTGGTTTTTAACTGCA
ACTCAGGATATTGCTGTTGATGGCTGGTGTCTTACTATGCTGCAGAGGAGAAATATTGGT
TATGCAGCTACGTGCAATAGTGTCGGTCAAACTGCAGGATGGTTCATAGGCTATGTTATT
TTGTTAGTTTTTGAATCAAAAGAATTTTGCAACAAATATATTTTTTCGGAACCACGCGAA
AAAGGATTGTTAACATTAGCAGGATTTTTAAACTTTTGGGGAGTTGTATTTCTTAGTACA
ACCATTTTGTTAGCACTTTTTAAAAAGGAAAGATCAGAATTTGAAGATGAACAGTTGAAA
AATAATCCTGACTATGGCATTAAGAAAGCTTATCCTATTTTATGGAAAATAATCACACAC
AAACCTGTCATGAAATTTTCAATTATTCTTCTCACAGTTAAAGCAAGTTTTGCCGCATGT
GATACTATAACGTCTTTAAAACTTATCGAGTATGGAGTGCCAAAAGATCGAATTGCATTA
CTTGCAATCCCTCTTGTGCCAGTTCAGATTGTGCTTCCTTTCATCATCAGTCGATATACA
GCTGGTCCAAAACCTATGCTTTTTTATATAAAAGCTTTTCCATATCGACTCATCATGACT
ATAGTGATTGCAGTTTGGGTTTTTTATACACCGAAAATGATAGTTGGAACTGATTTTCCC
GTTTATTATTATATCGCAATTGTTTCAATTTATATGATTTATCAGATTCCGTTTCGATCG
ATGTACGTTGCTGATATGAGCTTTTTCGCAAAAATATCTGATCCTTTAGTCGGAGGTACC
TATATGACCTTGATGAATACAATAAGCAACTTAGGGGGGTCGTGGATTCAAACTTTCTCC
CTTTGGTTAGTTGATATAATTACATGGAAGAGATGTATTTTTAGTGATAATGAGATACTG
AATGTTCAGAACTCTACTAACATTTCACTTAGTAATAATACTTGCAAAGATAAGATTGAA
AAAGAACAATGTGCGGAATTAGGTGGAAAATGTTTTACTGATATCGATGGTTATTATATA
GAAATTTGCATCAATGTGATTTATGGTATTATTTGGTTTTATTTCGGTCGAAAACTTATC
ATACATTTACAGAATTTACCCTCAAAAGATTGGTATATTTTGACTAAAAAAACAACAAAT
AACAAAGACGATAAAGAAAGTATTCCATTAAAGAAGATTCCATAG
>g10445.t1 Gene=g10445 Length=554
MSVDNKKIVRQDQEHQLTIKEEEKEQQEEEEEEESDLRGDYGNVAILLFLYILQGIPLGI
SSAVRILLTNRGVSYKELAILSFASYPFTMKVLWSPIVDAIYFKKIGRRKSWLIPVQLMI
GGFMIFLAQRVNDWMGDSKGQEPQIIFLTIVFFMLWFLTATQDIAVDGWCLTMLQRRNIG
YAATCNSVGQTAGWFIGYVILLVFESKEFCNKYIFSEPREKGLLTLAGFLNFWGVVFLST
TILLALFKKERSEFEDEQLKNNPDYGIKKAYPILWKIITHKPVMKFSIILLTVKASFAAC
DTITSLKLIEYGVPKDRIALLAIPLVPVQIVLPFIISRYTAGPKPMLFYIKAFPYRLIMT
IVIAVWVFYTPKMIVGTDFPVYYYIAIVSIYMIYQIPFRSMYVADMSFFAKISDPLVGGT
YMTLMNTISNLGGSWIQTFSLWLVDIITWKRCIFSDNEILNVQNSTNISLSNNTCKDKIE
KEQCAELGGKCFTDIDGYYIEICINVIYGIIWFYFGRKLIIHLQNLPSKDWYILTKKTTN
NKDDKESIPLKKIP
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g10445.t1 | Coils | Coil | Coil | 10 | 40 | - |
| 6 | g10445.t1 | Gene3D | G3DSA:1.20.1250.20 | MFS general substrate transporter like domains | 173 | 455 | 8.8E-11 |
| 41 | g10445.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 37 | - |
| 42 | g10445.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 23 | - |
| 3 | g10445.t1 | PANTHER | PTHR12778:SF9 | ACETYL-COENZYME A TRANSPORTER 1 | 30 | 537 | 1.4E-179 |
| 4 | g10445.t1 | PANTHER | PTHR12778 | SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED | 30 | 537 | 1.4E-179 |
| 2 | g10445.t1 | Pfam | PF13000 | Acetyl-coenzyme A transporter 1 | 45 | 253 | 2.6E-68 |
| 1 | g10445.t1 | Pfam | PF13000 | Acetyl-coenzyme A transporter 1 | 257 | 532 | 6.1E-37 |
| 19 | g10445.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 43 | - |
| 25 | g10445.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 44 | 68 | - |
| 13 | g10445.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 69 | 111 | - |
| 27 | g10445.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 112 | 131 | - |
| 18 | g10445.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 132 | 142 | - |
| 23 | g10445.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 143 | 160 | - |
| 12 | g10445.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 161 | 180 | - |
| 24 | g10445.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 181 | 204 | - |
| 15 | g10445.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 205 | 223 | - |
| 28 | g10445.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 224 | 247 | - |
| 11 | g10445.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 248 | 285 | - |
| 22 | g10445.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 286 | 306 | - |
| 14 | g10445.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 307 | 317 | - |
| 21 | g10445.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 318 | 336 | - |
| 8 | g10445.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 337 | 347 | - |
| 29 | g10445.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 348 | 369 | - |
| 17 | g10445.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 370 | 380 | - |
| 26 | g10445.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 381 | 404 | - |
| 9 | g10445.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 405 | 415 | - |
| 30 | g10445.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 416 | 436 | - |
| 16 | g10445.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 437 | 496 | - |
| 20 | g10445.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 497 | 515 | - |
| 10 | g10445.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 516 | 554 | - |
| 5 | g10445.t1 | SUPERFAMILY | SSF103473 | MFS general substrate transporter | 42 | 451 | 7.72E-22 |
| 39 | g10445.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 47 | 69 | - |
| 35 | g10445.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 79 | 98 | - |
| 40 | g10445.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 111 | 128 | - |
| 33 | g10445.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 143 | 160 | - |
| 31 | g10445.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 181 | 203 | - |
| 37 | g10445.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 223 | 245 | - |
| 32 | g10445.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 318 | 337 | - |
| 38 | g10445.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 352 | 369 | - |
| 34 | g10445.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 381 | 403 | - |
| 36 | g10445.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 497 | 516 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0008521 | acetyl-CoA transmembrane transporter activity | MF |
| GO:0016021 | integral component of membrane | CC |
KEGG
Orthology
- This transcript has been annotated with K03372 (MFS transporter, PAT family, solute carrier family 33 (acetyl-CoA transportor), member 1 [EC:2.3.1.-])
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
