General information for g10446.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Acetyl-coenzyme A transporter 1.
Parent gene
- The parent gene g10446 is located on chr_1: 9873334..9875542 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10446 | g10446.t1 | TSS | g10446.t1 | 9871504 | 9871504 |
| chr_1 | g10446 | g10446.t1 | isoform | g10446.t1 | 9871612 | 9873334 |
| chr_1 | g10446 | g10446.t1 | exon | g10446.t1.exon1 | 9871612 | 9871840 |
| chr_1 | g10446 | g10446.t1 | cds | g10446.t1.CDS1 | 9871612 | 9871840 |
| chr_1 | g10446 | g10446.t1 | exon | g10446.t1.exon2 | 9871898 | 9871950 |
| chr_1 | g10446 | g10446.t1 | cds | g10446.t1.CDS2 | 9871898 | 9871950 |
| chr_1 | g10446 | g10446.t1 | exon | g10446.t1.exon3 | 9872009 | 9873334 |
| chr_1 | g10446 | g10446.t1 | cds | g10446.t1.CDS3 | 9872009 | 9873334 |
| chr_1 | g10446 | g10446.t1 | TTS | g10446.t1 | 9873540 | 9873540 |
Sequences
>g10446.t1 Gene=g10446 Length=1608
ATGACGATACGAAAAAGAGGTGAAAGTTCGGACAGAAAGAAGTTGCTAACAAATCATCAT
GAAAGTGGCGAAGAGGAGGACATTCATGAACATTCAGATTTGCGAGGAGATTATTTGAAC
ATCGCATTACTATTTTTCCTTTATTTACTGCAAGGAATTCCACTTGGAATTGGTCAAGCA
ATTCCTATGCTTCTTCAGAATAGAGGAGCATCATATAAAGAACAAGCAGAGTTTTCATTT
GCCTATTGGCCTTTTTCAATTAAACTGCTTTGGGCACCTCTTGTAGATAGTATTTATTTT
AAAGCAATTGGAAGACGAAAGAGTTGGATGATCCCTACGCAGTATTTGATAGGAATTTTT
ATGTTAATTCTGTCACAACATGTGGGAAGTTGGCTCGGAGATGGTCATGAATCAATGCCT
CGAGTAGCTGTGATAACATTGATTTTCTTTTCATTAAATTTTCTCGCTGCAACACAAGAT
ATTGCAGTAGATGGTTGGGCTTTGTCAATGCTGAAAAAGAGAAATGTGGCTCATGCATCG
ACATGCAATTCAGTTGGACAGACAGCTGGCTATTTCCTAGGATATGTAGTATTCATGGCA
TTTGAATCAAAAGAATTTTGTAACAAATATATCTTTTCGGAGCCACGTGAACAAGGATTG
GTGACTCTTTCTGGTTTTCTTTATTTCTGGGGTGTAGTATTTTTGACTACAACCACCATC
ATTGGATTGCTCAAGAAAGAAAAGAAAGAGACTCAAGAGCAACTTGAAGAACATCCTGAT
TTGGGTATAAAAGAGACTTATACAATGTTGTGGAAAATTGTAACTATGAAACCAGTAATG
TTATTGGCTGTTTTACTTTTAACTGTTAAAGTCAGTTTTTCTGCTTGTGATGCAGTCACC
TCATTAAAATTGATTGATCATGGTATACCGAAAGAAAAATTGGCTATGTTGGCTATCCCA
CTCGTTCCACTACAACTTCTTTTACCTCTCATAATGAGCAAACACATCACAGGCAAATAT
CCAATGAACTTTTACATCAAGGCAATTCCATTTAGATTATTGCTCACACTTGTAACTGCT
GCAATCGTCTGGGCTACACCGCTCATCATAAGAGAACAAACAGATGACATTCCGTACTAC
TATTATGGTCTTTTACTCGTAACGTACTCTTTTTATCAAATATTTTTGTATGCAATGTTT
TGCTCTGCAATGAGTTTCTTTGCAAAAATTTCTGATCCTAAAATTGGCGGTACATATATG
ACTTTATTAAATACCCTGCATAATTTAGGAGGAAATTGGCCCAATACAATGGTCTTATGG
TTGATTGATTTCATAACATGGAAATCATGCGTTTCTGATGGAAATCAAAATAATTTTTCA
GCGCCAAAATTAAACGATAATGCATGTTTGACACATCAAGAACAAGAAGACTGCTTTAAA
ATTGGTGGTAAATGCAGAGTCGATATTGATGGTTATTATATCGAAGTCATTCTCTGTCTG
ATTTATGGAATTTTTTGGTATAAATGGGGCAGATCAAAGATCAATGAACTACAGAAATTA
CCAGTTAAAGCATGGCATGTTTTTCAATCAAAGACAAAATCGAGTTAG
>g10446.t1 Gene=g10446 Length=535
MTIRKRGESSDRKKLLTNHHESGEEEDIHEHSDLRGDYLNIALLFFLYLLQGIPLGIGQA
IPMLLQNRGASYKEQAEFSFAYWPFSIKLLWAPLVDSIYFKAIGRRKSWMIPTQYLIGIF
MLILSQHVGSWLGDGHESMPRVAVITLIFFSLNFLAATQDIAVDGWALSMLKKRNVAHAS
TCNSVGQTAGYFLGYVVFMAFESKEFCNKYIFSEPREQGLVTLSGFLYFWGVVFLTTTTI
IGLLKKEKKETQEQLEEHPDLGIKETYTMLWKIVTMKPVMLLAVLLLTVKVSFSACDAVT
SLKLIDHGIPKEKLAMLAIPLVPLQLLLPLIMSKHITGKYPMNFYIKAIPFRLLLTLVTA
AIVWATPLIIREQTDDIPYYYYGLLLVTYSFYQIFLYAMFCSAMSFFAKISDPKIGGTYM
TLLNTLHNLGGNWPNTMVLWLIDFITWKSCVSDGNQNNFSAPKLNDNACLTHQEQEDCFK
IGGKCRVDIDGYYIEVILCLIYGIFWYKWGRSKINELQKLPVKAWHVFQSKTKSS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 19 | g10446.t1 | Gene3D | G3DSA:1.20.1250.20 | MFS general substrate transporter like domains | 161 | 452 | 8.2E-11 |
| 18 | g10446.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 28 | - |
| 4 | g10446.t1 | PANTHER | PTHR12778:SF9 | ACETYL-COENZYME A TRANSPORTER 1 | 30 | 529 | 4.4E-189 |
| 5 | g10446.t1 | PANTHER | PTHR12778 | SOLUTE CARRIER FAMILY 33 ACETYL-COA TRANSPORTER -RELATED | 30 | 529 | 4.4E-189 |
| 3 | g10446.t1 | Pfam | PF13000 | Acetyl-coenzyme A transporter 1 | 41 | 252 | 2.4E-69 |
| 2 | g10446.t1 | Pfam | PF13000 | Acetyl-coenzyme A transporter 1 | 255 | 336 | 1.9E-11 |
| 1 | g10446.t1 | Pfam | PF13000 | Acetyl-coenzyme A transporter 1 | 370 | 527 | 1.5E-33 |
| 21 | g10446.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 37 | - |
| 34 | g10446.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 38 | 61 | - |
| 31 | g10446.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 62 | 80 | - |
| 33 | g10446.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 81 | 103 | - |
| 22 | g10446.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 104 | 114 | - |
| 32 | g10446.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 115 | 132 | - |
| 26 | g10446.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 133 | 137 | - |
| 39 | g10446.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 138 | 156 | - |
| 23 | g10446.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 157 | 175 | - |
| 41 | g10446.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 176 | 201 | - |
| 29 | g10446.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 202 | 220 | - |
| 37 | g10446.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 221 | 244 | - |
| 20 | g10446.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 245 | 278 | - |
| 40 | g10446.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 279 | 302 | - |
| 30 | g10446.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 303 | 313 | - |
| 42 | g10446.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 314 | 332 | - |
| 25 | g10446.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 333 | 343 | - |
| 35 | g10446.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 344 | 367 | - |
| 27 | g10446.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 368 | 378 | - |
| 38 | g10446.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 379 | 400 | - |
| 24 | g10446.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 401 | 491 | - |
| 36 | g10446.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 492 | 509 | - |
| 28 | g10446.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 510 | 535 | - |
| 17 | g10446.t1 | SUPERFAMILY | SSF103473 | MFS general substrate transporter | 24 | 449 | 2.35E-18 |
| 13 | g10446.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 41 | 63 | - |
| 16 | g10446.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 78 | 100 | - |
| 9 | g10446.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 107 | 129 | - |
| 6 | g10446.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 139 | 158 | - |
| 15 | g10446.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 179 | 201 | - |
| 7 | g10446.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 221 | 243 | - |
| 12 | g10446.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 279 | 301 | - |
| 10 | g10446.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 314 | 336 | - |
| 14 | g10446.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 348 | 370 | - |
| 11 | g10446.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 385 | 407 | - |
| 8 | g10446.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 491 | 510 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0008521 | acetyl-CoA transmembrane transporter activity | MF |
| GO:0016021 | integral component of membrane | CC |
KEGG
Orthology
- This transcript has been annotated with K03372 (MFS transporter, PAT family, solute carrier family 33 (acetyl-CoA transportor), member 1 [EC:2.3.1.-])
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
