General information for g10450.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Probable importin subunit beta-4.
Parent gene
- The parent gene g10450 is located on chr_1: 9881588..9882368 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10450 | g10450.t3 | TSS | g10450.t3 | 9878794 | 9878794 |
| chr_1 | g10450 | g10450.t3 | isoform | g10450.t3 | 9878900 | 9882368 |
| chr_1 | g10450 | g10450.t3 | exon | g10450.t3.exon1 | 9878900 | 9878956 |
| chr_1 | g10450 | g10450.t3 | cds | g10450.t3.CDS1 | 9878900 | 9878956 |
| chr_1 | g10450 | g10450.t3 | exon | g10450.t3.exon2 | 9879051 | 9879234 |
| chr_1 | g10450 | g10450.t3 | cds | g10450.t3.CDS2 | 9879051 | 9879234 |
| chr_1 | g10450 | g10450.t3 | exon | g10450.t3.exon3 | 9881701 | 9881872 |
| chr_1 | g10450 | g10450.t3 | cds | g10450.t3.CDS3 | 9881701 | 9881872 |
| chr_1 | g10450 | g10450.t3 | exon | g10450.t3.exon4 | 9881942 | 9882368 |
| chr_1 | g10450 | g10450.t3 | cds | g10450.t3.CDS4 | 9881942 | 9882368 |
| chr_1 | g10450 | g10450.t3 | TTS | g10450.t3 | 9882623 | 9882623 |
Sequences
>g10450.t3 Gene=g10450 Length=840
ATGGAGGCAATGGAAGCTATACTTAATAATCTTCTTAGTGCCGAAAATGTACAAAAGGCA
ACAGAAGAATTGAATGAAGTAATGAAGAGGCCGGAAGCAGTTTCAATGCTTTGTGAAGTT
ACATTTCGCAGTCAAAATGCTCAATTAAGACAATATGGTGCAGTTATTCTTAGAAAAAGA
TTATTAAAATTGAGAAATTGGAACATGATTCCGCCTGAGCAACAAGAAATAATTAAAAAT
GGAATAGTTTCAGAATGTTTTGAGCCACTAGGTGAATTTTCAGCAAGATATTTCGACGCA
TTGATTCCTCTCTTTCTCGAACTGATAAATGATCAGAGCGATGATGAAGTGAGAAATAAT
GCAGTGTACGCGATTGGGGAATTAAGCAAACACAGTGGACAAGCTAGTTTTAAAGCATAT
CCACAAATTTTAGCAGCATTATCAAATTTAGTTTCAAAAGAAAGTCATGGTGGAATTCTC
GATAATATTTGTGGTACACTCGCTCGATTGATTATTACAAATAGCACATTGGTTCCTTTA
AAAGATGTTCTCCCAGTTTTTATATCTTATCTTCCACTTCGACAAGACTATGTTGAAAAT
GAGCACGTATTTAAATCACTCGAATTATTATATCGACAAGGAAATGAAGTTTTGTTGCAA
TTCCTTGAGCGCGTGATTCTTACAGCATTAACTGTTTTACAAAAAAATCAATATAACAAC
GATGCAGTACGAGAGCACATTTTTCAATTTGTTAAACAAGTTAGGATAGACTTTCCGGAA
AAATTTAATAATGCTATCAATGTTGATGCAGAAATTTCAAGTTTTGTACAAACATTGTAA
>g10450.t3 Gene=g10450 Length=279
MEAMEAILNNLLSAENVQKATEELNEVMKRPEAVSMLCEVTFRSQNAQLRQYGAVILRKR
LLKLRNWNMIPPEQQEIIKNGIVSECFEPLGEFSARYFDALIPLFLELINDQSDDEVRNN
AVYAIGELSKHSGQASFKAYPQILAALSNLVSKESHGGILDNICGTLARLIITNSTLVPL
KDVLPVFISYLPLRQDYVENEHVFKSLELLYRQGNEVLLQFLERVILTALTVLQKNQYNN
DAVREHIFQFVKQVRIDFPEKFNNAINVDAEISSFVQTL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g10450.t3 | Gene3D | G3DSA:1.25.10.10 | - | 1 | 85 | 0.0000000 |
| 6 | g10450.t3 | Gene3D | G3DSA:1.25.10.10 | - | 86 | 274 | 0.0000000 |
| 3 | g10450.t3 | PANTHER | PTHR10527:SF6 | IMPORTIN-4 | 107 | 254 | 0.0000000 |
| 4 | g10450.t3 | PANTHER | PTHR10527 | IMPORTIN BETA | 107 | 254 | 0.0000000 |
| 2 | g10450.t3 | Pfam | PF03810 | Importin-beta N-terminal domain | 20 | 83 | 0.0000003 |
| 1 | g10450.t3 | Pfam | PF02985 | HEAT repeat | 101 | 131 | 0.0000250 |
| 8 | g10450.t3 | ProSiteProfiles | PS50166 | Importin-beta N-terminal domain profile. | 20 | 88 | 9.6220000 |
| 9 | g10450.t3 | ProSiteProfiles | PS50077 | HEAT repeat profile. | 101 | 140 | 11.8380000 |
| 5 | g10450.t3 | SUPERFAMILY | SSF48371 | ARM repeat | 5 | 265 | 0.0000000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0031267 | small GTPase binding | MF |
| GO:0006886 | intracellular protein transport | BP |
| GO:0005515 | protein binding | MF |
| GO:0006606 | protein import into nucleus | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
