General information for g10450.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Importin-4.
Parent gene
- The parent gene g10450 is located on chr_1: 9881588..9882368 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10450 | g10450.t4 | isoform | g10450.t4 | 9880785 | 9882368 |
| chr_1 | g10450 | g10450.t4 | exon | g10450.t4.exon1 | 9880785 | 9881588 |
| chr_1 | g10450 | g10450.t4 | cds | g10450.t4.CDS1 | 9880803 | 9881588 |
| chr_1 | g10450 | g10450.t4 | exon | g10450.t4.exon2 | 9881646 | 9881872 |
| chr_1 | g10450 | g10450.t4 | cds | g10450.t4.CDS2 | 9881646 | 9881872 |
| chr_1 | g10450 | g10450.t4 | exon | g10450.t4.exon3 | 9881942 | 9882368 |
| chr_1 | g10450 | g10450.t4 | cds | g10450.t4.CDS3 | 9881942 | 9882368 |
| chr_1 | g10450 | g10450.t4 | TTS | g10450.t4 | 9882623 | 9882623 |
| chr_1 | g10450 | g10450.t4 | TSS | g10450.t4 | NA | NA |
Sequences
>g10450.t4 Gene=g10450 Length=1458
TACAATTTGTTTGCAGCAATGGCATCAATCCTTAATGAACAAATCGGATCAGCTTTAGAA
AGAATTGTAACATCAATGATTGATAGTGTGAAATCAACTGAAAGCATCGTTCTGTCAAGT
GGTAAAGACTCGGATGATATTGAAGAACAAGAAAATGATGACGATGGCGAATTTGATATT
GAAAATTCTGATGGTGAAGAAGAAGATGAGGATGAAATTTTGGGAGTAGAAAATGCATAC
ATGGAAGAAAAAGAAGAAGCAATCATTGCATTGAAAGAACTTGCAGAACATACTGGTCCT
GCTTTTGCTCCTTACATTAAAGTTTCATTTGAAGAAATTTATAAATTACTCCCTTATCCT
AATGAAGACATTCGTCAATCATCTGTTGAGGCTTTGTGCCAATTCGTTATAGCTTTACAT
AAATTGCACAATGTTCAAGGAGTTAAACATACATTGTCAATCCTTATACCAAAATTAAGC
GAAATAATTCATGTAGATGAAGAAAGAATTGTTGTTATGGCAGCTCTAGAAAGTTTTAAT
CAAATTTTAGAAGAATTGGGTAAAGCAGCAGTTGAAGTTGATGGATATAAAGATGCAATT
TTTTCATGCATTTATGATGTTTTAAATAATAAAGTTCAATGTCAATTCGACGAGCCAGAA
GAAGATGATGAAGATGAAAGTGAATATGATATTGCAATATTAGAATCAGCTGGTGAAATA
CTTCCTAAATTTGGCAAAACAATGAGCAATCAAGAATTTTACGTCTATTTTGAGAGAGTC
TCAGAGTTCTTTGCTGGAAAAATTCAAAAATCAAAGAGTAGAGATGAACTTTCTCAATCA
CAACGTGCTATGGCAGTAGGAATAGTTTCAGAATGTTTTGAGCCACTAGGTGAATTTTCA
GCAAGATATTTCGACGCATTGATTCCTCTCTTTCTCGAACTGATAAATGATCAGAGCGAT
GATGAAGTGAGAAATAATGCAGTGTACGCGATTGGGGAATTAAGCAAACACAGTGGACAA
GCTAGTTTTAAAGCATATCCACAAATTTTAGCAGCATTATCAAATTTAGTTTCAAAAGAA
AGTCATGGTGGAATTCTCGATAATATTTGTGGTACACTCGCTCGATTGATTATTACAAAT
AGCACATTGGTTCCTTTAAAAGATGTTCTCCCAGTTTTTATATCTTATCTTCCACTTCGA
CAAGACTATGTTGAAAATGAGCACGTATTTAAATCACTCGAATTATTATATCGACAAGGA
AATGAAGTTTTGTTGCAATTCCTTGAGCGCGTGATTCTTACAGCATTAACTGTTTTACAA
AAAAATCAATATAACAACGATGCAGTACGAGAGCACATTTTTCAATTTGTTAAACAAGTT
AGGATAGACTTTCCGGAAAAATTTAATAATGCTATCAATGTTGATGCAGAAATTTCAAGT
TTTGTACAAACATTGTAA
>g10450.t4 Gene=g10450 Length=479
MASILNEQIGSALERIVTSMIDSVKSTESIVLSSGKDSDDIEEQENDDDGEFDIENSDGE
EEDEDEILGVENAYMEEKEEAIIALKELAEHTGPAFAPYIKVSFEEIYKLLPYPNEDIRQ
SSVEALCQFVIALHKLHNVQGVKHTLSILIPKLSEIIHVDEERIVVMAALESFNQILEEL
GKAAVEVDGYKDAIFSCIYDVLNNKVQCQFDEPEEDDEDESEYDIAILESAGEILPKFGK
TMSNQEFYVYFERVSEFFAGKIQKSKSRDELSQSQRAMAVGIVSECFEPLGEFSARYFDA
LIPLFLELINDQSDDEVRNNAVYAIGELSKHSGQASFKAYPQILAALSNLVSKESHGGIL
DNICGTLARLIITNSTLVPLKDVLPVFISYLPLRQDYVENEHVFKSLELLYRQGNEVLLQ
FLERVILTALTVLQKNQYNNDAVREHIFQFVKQVRIDFPEKFNNAINVDAEISSFVQTL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g10450.t4 | MobiDBLite | mobidb-lite | consensus disorder prediction | 28 | 65 | - |
| 6 | g10450.t4 | MobiDBLite | mobidb-lite | consensus disorder prediction | 40 | 65 | - |
| 2 | g10450.t4 | PANTHER | PTHR10527:SF6 | IMPORTIN-4 | 1 | 454 | 1.8E-67 |
| 3 | g10450.t4 | PANTHER | PTHR10527 | IMPORTIN BETA | 1 | 454 | 1.8E-67 |
| 1 | g10450.t4 | Pfam | PF02985 | HEAT repeat | 301 | 331 | 5.2E-5 |
| 7 | g10450.t4 | ProSiteProfiles | PS50077 | HEAT repeat profile. | 301 | 340 | 11.838 |
| 4 | g10450.t4 | SUPERFAMILY | SSF48371 | ARM repeat | 74 | 461 | 2.82E-35 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
| GO:0006606 | protein import into nucleus | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
