General information for g10496.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Heparan-alpha-glucosaminide N-acetyltransferase.
Parent gene
- The parent gene g10496 is located on chr_1: 10206484..10207553 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10496 | g10496.t1 | TTS | g10496.t1 | 10204496 | 10204496 |
| chr_1 | g10496 | g10496.t1 | isoform | g10496.t1 | 10204623 | 10206484 |
| chr_1 | g10496 | g10496.t1 | exon | g10496.t1.exon1 | 10204623 | 10205564 |
| chr_1 | g10496 | g10496.t1 | cds | g10496.t1.CDS1 | 10204623 | 10205564 |
| chr_1 | g10496 | g10496.t1 | exon | g10496.t1.exon2 | 10205623 | 10206017 |
| chr_1 | g10496 | g10496.t1 | cds | g10496.t1.CDS2 | 10205623 | 10206017 |
| chr_1 | g10496 | g10496.t1 | exon | g10496.t1.exon3 | 10206091 | 10206484 |
| chr_1 | g10496 | g10496.t1 | cds | g10496.t1.CDS3 | 10206091 | 10206484 |
| chr_1 | g10496 | g10496.t1 | TSS | g10496.t1 | 10206717 | 10206717 |
Sequences
>g10496.t1 Gene=g10496 Length=1731
ATGTCTTGGCTAGAATGGACAGACAGCAGCTTTCGTGGTCTTGATTTGACAAAATTAAAA
GTCGATCAGGCTTATTTTAATATTAGTAATGGAATGAATCAACATTTTTATCTCTATACA
CTCTCACAAGAGTGTATATCATGTCCATTCAGAAAAATCAAAAAAGCTGCAGCATTAAAT
GATACAATTTTGAAACTTGATACAACTCGTAGAATTGAATTGCGTCTTTTCACTAAAGAT
CATGGCCCATTTGTGCATCCAAATGTAGTTGTTGATAATGTCTTTTGGAGTATGCAAGAG
CAGCTTGGTGAATTTGGTGTTTATGATCTTACAATCAAACCTTCTGGTGCAACAGCATTC
GAAATTGCAAAGGAGCCAGTCAGCACATTTTCATCACTCATTATCGTGTTATTCATCGTC
CTATGTATTTATTGGATATTCAAATATATCAACAAATTCTACATAAAAAGACTAGCAAGT
CAAGTGACTGAAATTAATATACCACCTGATTCACCTGAAAATGTGAATGAACCAAGTGAA
CCAAAAACAAAGAAAAGACTTAAAAGTTTGGATATTTTTCGCGGAATTGCAATCGTTTTG
ATGATTTTTGTCAATAGTGGTGGTGGTCATTATTGGTGGATTGAACATGCAATTTGGAAT
GGTTTGCACTTTGCTGATTTAGTTTTTCCCTGGTTTTTATTTATAATGGGAGTTTGCATA
CCTTTAAGTATCAAATCGCAAATTAATCGACAAGTCGCTATGTCTAGTATTGTAAAGAAA
GTTATCAAGCGGTCAATCACATTATTTCTCCTTGGTTTATGTCTCAATACGCTATATGGT
GCGTCTTTTCAAAGCATTCGTATAATGGGAGTTTTGCAACGATTTGGAATCGCTTATTTG
GTTATTTCACTTATTCATCTTGCTTTTGTCAGCAATTCAATCAATGCAGAAACAAGAATC
CAACAGTTATTTTATGATGTTCGAATGATATGGAAACAATGGTTGATTGTTCTTAGTTTT
GTAATCTTCCACTTGATTATGATTTTTGGAATAAAAGCATCAAATTGTGAGCGAGGATAT
TTTGGTCCAGGTGGTATTCATGAATACATGGCACATGAAAATTGCACGGGTGGCATCGCT
GGATTTGTTGATCGAAATGTTTTGGGTGAGAGTCACATGTATCAACGTGCGAAAATTCGA
TCAGTTTATGATGCTCAAGTATTTGATCCTGAAGGAGTTTTTGGATGCTTGCTGACATGT
TTGCAAGTATTTTTGGGTCTCCAGTGTGGAGTTACTTTATTGGTTTACCCAACAGCAAAA
GAAAGATTAAGACGATGGATAATTTGGGGAATTGGATTGCTGATTCTTACATGTTTTTTA
ACTTTTTTCTCAGTTGAAAATGGTCTCATACCAATTAATAAGAATTTATGGTCATTATCA
TTTGTTACCATCACTGCAGGCTTAGCATTTCTTCTTCTTAGTTTAATTTATTTTTTGGTT
GATGTTAAAAACATTGGTGACGATTTTTGGACAATTTTCTTATATCCTGGAATGAATGCG
ATTGTTCTTTATGTAGGTCACTCTGTCTTTCACAGCATGTGGCCTTTTCATTGGTCAGTT
GATAATATGAACACTCATTTTCTTTTGCTACTAGAAAATTTATATACTGTCATGATTTGG
GTACTCATTTCCCACTATTTGTATCACAAAGAACTGTTTTATAATATTTAA
>g10496.t1 Gene=g10496 Length=576
MSWLEWTDSSFRGLDLTKLKVDQAYFNISNGMNQHFYLYTLSQECISCPFRKIKKAAALN
DTILKLDTTRRIELRLFTKDHGPFVHPNVVVDNVFWSMQEQLGEFGVYDLTIKPSGATAF
EIAKEPVSTFSSLIIVLFIVLCIYWIFKYINKFYIKRLASQVTEINIPPDSPENVNEPSE
PKTKKRLKSLDIFRGIAIVLMIFVNSGGGHYWWIEHAIWNGLHFADLVFPWFLFIMGVCI
PLSIKSQINRQVAMSSIVKKVIKRSITLFLLGLCLNTLYGASFQSIRIMGVLQRFGIAYL
VISLIHLAFVSNSINAETRIQQLFYDVRMIWKQWLIVLSFVIFHLIMIFGIKASNCERGY
FGPGGIHEYMAHENCTGGIAGFVDRNVLGESHMYQRAKIRSVYDAQVFDPEGVFGCLLTC
LQVFLGLQCGVTLLVYPTAKERLRRWIIWGIGLLILTCFLTFFSVENGLIPINKNLWSLS
FVTITAGLAFLLLSLIYFLVDVKNIGDDFWTIFLYPGMNAIVLYVGHSVFHSMWPFHWSV
DNMNTHFLLLLENLYTVMIWVLISHYLYHKELFYNI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 2 | g10496.t1 | PANTHER | PTHR31061 | LD22376P | 161 | 573 | 1.9E-113 |
| 3 | g10496.t1 | PANTHER | PTHR31061:SF19 | HEPARAN-ALPHA-GLUCOSAMINIDE N-ACETYLTRANSFERASE | 161 | 573 | 1.9E-113 |
| 1 | g10496.t1 | Pfam | PF16401 | Domain of unknown function (DUF5009) | 186 | 276 | 1.7E-8 |
| 22 | g10496.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 126 | - |
| 33 | g10496.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 127 | 147 | - |
| 20 | g10496.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 148 | 191 | - |
| 30 | g10496.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 192 | 212 | - |
| 26 | g10496.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 213 | 223 | - |
| 34 | g10496.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 224 | 244 | - |
| 15 | g10496.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 245 | 264 | - |
| 27 | g10496.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 265 | 283 | - |
| 25 | g10496.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 284 | 294 | - |
| 31 | g10496.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 295 | 314 | - |
| 17 | g10496.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 315 | 333 | - |
| 37 | g10496.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 334 | 351 | - |
| 21 | g10496.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 352 | 411 | - |
| 36 | g10496.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 412 | 434 | - |
| 19 | g10496.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 435 | 445 | - |
| 29 | g10496.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 446 | 465 | - |
| 24 | g10496.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 466 | 476 | - |
| 35 | g10496.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 477 | 500 | - |
| 18 | g10496.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 501 | 511 | - |
| 28 | g10496.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 512 | 534 | - |
| 23 | g10496.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 535 | 545 | - |
| 32 | g10496.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 546 | 568 | - |
| 16 | g10496.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 569 | 576 | - |
| 6 | g10496.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 128 | 147 | - |
| 11 | g10496.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 192 | 214 | - |
| 8 | g10496.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 227 | 244 | - |
| 12 | g10496.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 265 | 287 | - |
| 10 | g10496.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 291 | 313 | - |
| 14 | g10496.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 334 | 351 | - |
| 13 | g10496.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 412 | 434 | - |
| 7 | g10496.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 446 | 465 | - |
| 4 | g10496.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 480 | 502 | - |
| 5 | g10496.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 509 | 531 | - |
| 9 | g10496.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 546 | 568 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005765 | lysosomal membrane | CC |
| GO:0015019 | heparan-alpha-glucosaminide N-acetyltransferase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K10532 (heparan-alpha-glucosaminide N-acetyltransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
