General information for g10514.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Transcription elongation regulator 1.
Parent gene
- The parent gene g10514 is located on chr_1: 10311027..10311614 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10514 | g10514.t1 | TSS | g10514.t1 | 10306433 | 10306433 |
| chr_1 | g10514 | g10514.t1 | isoform | g10514.t1 | 10306541 | 10311027 |
| chr_1 | g10514 | g10514.t1 | exon | g10514.t1.exon1 | 10306541 | 10306629 |
| chr_1 | g10514 | g10514.t1 | cds | g10514.t1.CDS1 | 10306541 | 10306629 |
| chr_1 | g10514 | g10514.t1 | exon | g10514.t1.exon2 | 10306716 | 10306929 |
| chr_1 | g10514 | g10514.t1 | cds | g10514.t1.CDS2 | 10306716 | 10306929 |
| chr_1 | g10514 | g10514.t1 | exon | g10514.t1.exon3 | 10306998 | 10307212 |
| chr_1 | g10514 | g10514.t1 | cds | g10514.t1.CDS3 | 10306998 | 10307212 |
| chr_1 | g10514 | g10514.t1 | exon | g10514.t1.exon4 | 10307269 | 10307906 |
| chr_1 | g10514 | g10514.t1 | cds | g10514.t1.CDS4 | 10307269 | 10307906 |
| chr_1 | g10514 | g10514.t1 | exon | g10514.t1.exon5 | 10307969 | 10308166 |
| chr_1 | g10514 | g10514.t1 | cds | g10514.t1.CDS5 | 10307969 | 10308166 |
| chr_1 | g10514 | g10514.t1 | exon | g10514.t1.exon6 | 10308232 | 10308616 |
| chr_1 | g10514 | g10514.t1 | cds | g10514.t1.CDS6 | 10308232 | 10308616 |
| chr_1 | g10514 | g10514.t1 | exon | g10514.t1.exon7 | 10308674 | 10308824 |
| chr_1 | g10514 | g10514.t1 | cds | g10514.t1.CDS7 | 10308674 | 10308824 |
| chr_1 | g10514 | g10514.t1 | exon | g10514.t1.exon8 | 10309704 | 10310603 |
| chr_1 | g10514 | g10514.t1 | cds | g10514.t1.CDS8 | 10309704 | 10310603 |
| chr_1 | g10514 | g10514.t1 | exon | g10514.t1.exon9 | 10310677 | 10310846 |
| chr_1 | g10514 | g10514.t1 | cds | g10514.t1.CDS9 | 10310677 | 10310846 |
| chr_1 | g10514 | g10514.t1 | exon | g10514.t1.exon10 | 10310901 | 10311027 |
| chr_1 | g10514 | g10514.t1 | cds | g10514.t1.CDS10 | 10310901 | 10311027 |
| chr_1 | g10514 | g10514.t1 | TTS | g10514.t1 | 10311103 | 10311103 |
Sequences
>g10514.t1 Gene=g10514 Length=3087
ATGGACACAGAAGTTCCAATTATTGAAGGAGCTGACGAAAAACAAGCTGAAAATGCATTT
TCTGAAGATTTTTCAGCGGATTTTGAAAATGGTTGGAATAATGAAAACACAAATAATCAA
CAGCCAATAAGTCAAGTACAGTCCGAAAATCGTTTCCCGAACAACAACAGTCGAAATCAA
AATAGTAATCGGGCTAAATCAGGCAATCGTGGTGGAGGAAGTAGAGGAGGAGGAAGTCAT
AATAATAATTGGAATCCACATCAACAACAACAGAATCCAGTAACGCAGCAACAACCTCCA
ACACAACAAGAATTATGGGTTGAAACAAAAACAAATGATGGAAAATCATATTTTTATCAT
GCTGTTACACGTGAAACAACTTGGAATCGACCAGAAGGTCCAAATATAAAAATTATGACA
CAACCAGAATATGAAGCTTACACAAGACAACAAATGATTGCCAATAAACCTATAGAACAA
AACATAAATGATCCAAATTTGAAACAGCCAGCGATGGGAATGATTCCTAATTTAATGGAT
CAACCACCACCGTTTTTTAATGCTAATATTTCGCCATTTGGTTTACATGCTCCTCCTCAT
TTTAATGCCCCATGGCAAAATCCTCAATGGCAGCAACATCCAGGGGGTGATCCGGCAAAG
ATGTTTGACAATAAAATTGATCCGAAAATATTGGCTAAAGCGGCTGAATGGAGTGAACAT
CGTGCACCTGATGGTCGTTTATATTATTATAGTGCTACGCGTGGTGAGAGTGTATGGGAA
AAACCTCAAGCTTTAAAAGATCTTGACATTGCGAGGAGTGCTTTCATGCAACAACAACAA
CCAACTTCTCTTGCACCACCACCTATGACAATGACACAAGGTAGTATAACATTTGACTCT
TCTGGTAATATGGTAAAGCCTGGCGCATTATTGAACAAACAAGCTGAAATTGAAGCTGCA
GAAAAAGAACGTAAACGAAAAGAAGAACTTGAGAAATCAAAACAACCAGCTAAACCGCAA
GACAAATCTCGACCAATTTCAAGCACTGCGATTGCAGGTACTCCTTGGTGTGTTGTGTGG
ACAGGTGATAGCAGATGTTTCTTTTATAATCCTTCAACTCGTACGAGCGTATGGCAGCGA
CCAGAAGATCTTATTGGACGTGCGGATGTCGATAAGCTGGTTTCAACAATACCCGACCAA
CTTAAAGGAACGGTAAGCGAAAAAGAGGAGCAGGTTAGTGAAACACCTAGTAATACAGGT
AAAAAGAATGAACCAGAGAAGATTGTTGAAGAAGAAGAAGAATCCGAAGAAGAAGATGAA
GAGGTTCCAGCAGCTAAAAAATCTAAAATTGAAGAGCAAGTTACCTCGGCACCAGTGAAA
ATTCAAAATGCACCTGCTATTCCGGAGAAAAAAGTTGATATCGTAAAAGATCCAGCAGCA
GAAGCGGAGTTGAAAGCTGCGAAAGAGAGAGCGATGGTTCCACTAGAGACCAGAGTTAAA
CAGTTTAAAGAAATGTTAAAAGAAAAAGAAGTTTCAGCTTTCAGTACATGGGAAAAGGAA
TTACATAAGATCGTTTTTGATCCTCGTTATTTGCTTTTAGCTAGCAAAGAACGTAAACAA
GTTTTCGAAAAATATGTGAAAGATCGAGCTGAAGATGAGAGAAGAGAAAAGCGATATAAA
ATGCAAAAAAAACGAGATGATTTTAAAAAGTTGATGGAAGATGCCAATCTTCATTCGAGA
TCAAGCTTTTCAGATTTTTGTTCGAGATACAGTCGAGATGAGCGTTATAAAGGTATCGAA
AAAATGCGTGAACGTGAGAATTTATTCAATGACTTCCTTAGTGATTTGCGTCGCAAAGAA
AAGGATGAAAAGCATCAAAAGAAGGAACAGATTCGCAAAGACTTTTTTGATTTATTAAAA
GAACATTCTGAGATTGATCGTCATACGCATTGGATGGATATCAAAAAGAGCTTAGATCAA
GATTCTCGTTATAAAGCAGTATCTGATTCAATTTTACGTGAAGACTATTTCTATGAGTAC
ATAAAAATACTCAAGGAAGAACGCAAAAAAGAAAAGTCGAAGAAATCCAAAAAATCGGAG
AAAAAAGACAAGAAAAAGAAATCAAAAGATAAAGATCGTTCACGAAATGATTCTTCAAGC
AAAAATCAGAGTGAAACAATCAATATTGATGATGATGACGATATGTCTGAGAAAAAAGAT
CAAGATAAAGTGACAAATATGGACGTGGAAGATGATAATAAATCAGAAATGGAAGTTGAC
AAATCAGGTTCTGATAGTGACAAAGATCAGGAAGATGGCGAACATTCGGGAACAGACGAA
GACAGTGAATCAGAAAAAGCTCGAAAAGAACGAGAGCGTCAACTGAGAGCTGAAGCAAGT
ATAAAAGAGCGAGAAAAACAAGTCCAGAAAAAACTTGCAGAACACTTACGTGATCGAGAT
AAGGAGAGACAACATCATCAAAGAGATGAAGCCATTAGAAACTTTTCGGCATTACTTGCA
GATTTAGTTCGTAATCCTGATTTAACATGGAAAGAAGTTAAAAAACTACTTAAAAGAGAT
CACCGTTATGAAGCAGCTGAAGAACTTGATCGAGATGAGCGTGAACGTCTTTTCAATGAA
CACATCAACCTTTTGACTAAAAAGAAGCGTGACAAGTTTCGTGAAATGCTAGATGAGATT
TCATCATTAGAATTAACAAGCTCTTGGAAAGACATTAAAAAGATAATACGAGATGATCCA
AGATATATAAAATTTGGAAATTCTGATAAGTGCGAACGAGAATTTAGAGAGTATCTCAGA
GATAAATCATCTTCTGCAAAAACATCTTTCAAAGAACTTTTGCTTGAGTGTAAATTAATT
AACCATAAATCTTACGATACTTACAAAGAGAATCACAATCATCTTAAGGAAATTGAAGAT
ATTCTGAAAAATGATAAAAGGTATCTCGTATTGGAACATATGTCAAGAGAGAGAACTGAC
ATGATTTTAGATTATTTTGAGGAGCTTAAAAAGAAGGGTGTACCAGCACCAATAACGAGT
GTTGAAAGTAATCGTAGGAAGAAGTAA
>g10514.t1 Gene=g10514 Length=1028
MDTEVPIIEGADEKQAENAFSEDFSADFENGWNNENTNNQQPISQVQSENRFPNNNSRNQ
NSNRAKSGNRGGGSRGGGSHNNNWNPHQQQQNPVTQQQPPTQQELWVETKTNDGKSYFYH
AVTRETTWNRPEGPNIKIMTQPEYEAYTRQQMIANKPIEQNINDPNLKQPAMGMIPNLMD
QPPPFFNANISPFGLHAPPHFNAPWQNPQWQQHPGGDPAKMFDNKIDPKILAKAAEWSEH
RAPDGRLYYYSATRGESVWEKPQALKDLDIARSAFMQQQQPTSLAPPPMTMTQGSITFDS
SGNMVKPGALLNKQAEIEAAEKERKRKEELEKSKQPAKPQDKSRPISSTAIAGTPWCVVW
TGDSRCFFYNPSTRTSVWQRPEDLIGRADVDKLVSTIPDQLKGTVSEKEEQVSETPSNTG
KKNEPEKIVEEEEESEEEDEEVPAAKKSKIEEQVTSAPVKIQNAPAIPEKKVDIVKDPAA
EAELKAAKERAMVPLETRVKQFKEMLKEKEVSAFSTWEKELHKIVFDPRYLLLASKERKQ
VFEKYVKDRAEDERREKRYKMQKKRDDFKKLMEDANLHSRSSFSDFCSRYSRDERYKGIE
KMRERENLFNDFLSDLRRKEKDEKHQKKEQIRKDFFDLLKEHSEIDRHTHWMDIKKSLDQ
DSRYKAVSDSILREDYFYEYIKILKEERKKEKSKKSKKSEKKDKKKKSKDKDRSRNDSSS
KNQSETINIDDDDDMSEKKDQDKVTNMDVEDDNKSEMEVDKSGSDSDKDQEDGEHSGTDE
DSESEKARKERERQLRAEASIKEREKQVQKKLAEHLRDRDKERQHHQRDEAIRNFSALLA
DLVRNPDLTWKEVKKLLKRDHRYEAAEELDRDERERLFNEHINLLTKKKRDKFREMLDEI
SSLELTSSWKDIKKIIRDDPRYIKFGNSDKCEREFREYLRDKSSSAKTSFKELLLECKLI
NHKSYDTYKENHNHLKEIEDILKNDKRYLVLEHMSRERTDMILDYFEELKKKGVPAPITS
VESNRRKK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 32 | g10514.t1 | CDD | cd00201 | WW | 106 | 133 | 7.90865E-8 |
| 33 | g10514.t1 | CDD | cd00201 | WW | 235 | 262 | 6.16404E-5 |
| 31 | g10514.t1 | CDD | cd00201 | WW | 354 | 383 | 1.51393E-5 |
| 26 | g10514.t1 | Coils | Coil | Coil | 310 | 333 | - |
| 27 | g10514.t1 | Coils | Coil | Coil | 547 | 567 | - |
| 30 | g10514.t1 | Coils | Coil | Coil | 613 | 633 | - |
| 29 | g10514.t1 | Coils | Coil | Coil | 681 | 701 | - |
| 28 | g10514.t1 | Coils | Coil | Coil | 1026 | 1028 | - |
| 25 | g10514.t1 | Gene3D | G3DSA:2.20.70.10 | - | 85 | 156 | 3.6E-12 |
| 23 | g10514.t1 | Gene3D | G3DSA:2.20.70.10 | - | 224 | 283 | 4.5E-11 |
| 24 | g10514.t1 | Gene3D | G3DSA:2.20.70.10 | - | 336 | 407 | 2.6E-20 |
| 21 | g10514.t1 | Gene3D | G3DSA:1.10.10.440 | - | 490 | 559 | 6.3E-23 |
| 18 | g10514.t1 | Gene3D | G3DSA:1.10.10.440 | - | 560 | 617 | 1.9E-13 |
| 17 | g10514.t1 | Gene3D | G3DSA:1.10.10.440 | - | 618 | 697 | 5.9E-19 |
| 20 | g10514.t1 | Gene3D | G3DSA:1.10.10.440 | - | 824 | 884 | 1.1E-20 |
| 22 | g10514.t1 | Gene3D | G3DSA:1.10.10.440 | - | 886 | 943 | 1.1E-16 |
| 19 | g10514.t1 | Gene3D | G3DSA:1.10.10.440 | - | 946 | 1012 | 5.7E-23 |
| 46 | g10514.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 79 | - |
| 48 | g10514.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 27 | 79 | - |
| 44 | g10514.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 320 | 339 | - |
| 51 | g10514.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 320 | 347 | - |
| 49 | g10514.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 401 | 462 | - |
| 50 | g10514.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 688 | 829 | - |
| 45 | g10514.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 705 | 719 | - |
| 47 | g10514.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 726 | 829 | - |
| 8 | g10514.t1 | PANTHER | PTHR15377 | TRANSCRIPTION ELONGATION REGULATOR 1 | 40 | 987 | 2.5E-225 |
| 7 | g10514.t1 | Pfam | PF00397 | WW domain | 106 | 131 | 8.6E-7 |
| 4 | g10514.t1 | Pfam | PF01846 | FF domain | 500 | 545 | 1.0E-11 |
| 6 | g10514.t1 | Pfam | PF01846 | FF domain | 563 | 612 | 1.2E-9 |
| 1 | g10514.t1 | Pfam | PF01846 | FF domain | 631 | 680 | 2.6E-11 |
| 3 | g10514.t1 | Pfam | PF01846 | FF domain | 830 | 881 | 5.7E-10 |
| 2 | g10514.t1 | Pfam | PF01846 | FF domain | 888 | 937 | 1.1E-9 |
| 5 | g10514.t1 | Pfam | PF01846 | FF domain | 946 | 1005 | 7.0E-12 |
| 43 | g10514.t1 | ProSitePatterns | PS01159 | WW/rsp5/WWP domain signature. | 106 | 131 | - |
| 60 | g10514.t1 | ProSiteProfiles | PS50020 | WW/rsp5/WWP domain profile. | 106 | 133 | 11.822 |
| 59 | g10514.t1 | ProSiteProfiles | PS50020 | WW/rsp5/WWP domain profile. | 237 | 264 | 10.64 |
| 58 | g10514.t1 | ProSiteProfiles | PS50020 | WW/rsp5/WWP domain profile. | 354 | 383 | 10.66 |
| 56 | g10514.t1 | ProSiteProfiles | PS51676 | FF domain profile. | 495 | 548 | 11.831 |
| 54 | g10514.t1 | ProSiteProfiles | PS51676 | FF domain profile. | 560 | 615 | 10.767 |
| 55 | g10514.t1 | ProSiteProfiles | PS51676 | FF domain profile. | 628 | 683 | 10.082 |
| 57 | g10514.t1 | ProSiteProfiles | PS51676 | FF domain profile. | 828 | 884 | 9.569 |
| 52 | g10514.t1 | ProSiteProfiles | PS51676 | FF domain profile. | 886 | 941 | 11.182 |
| 53 | g10514.t1 | ProSiteProfiles | PS51676 | FF domain profile. | 942 | 1008 | 7.248 |
| 42 | g10514.t1 | SMART | SM00456 | ww_5 | 101 | 133 | 7.8E-8 |
| 41 | g10514.t1 | SMART | SM00456 | ww_5 | 232 | 264 | 0.0071 |
| 40 | g10514.t1 | SMART | SM00456 | ww_5 | 351 | 383 | 2.5E-5 |
| 37 | g10514.t1 | SMART | SM00441 | FF_2 | 495 | 548 | 1.4E-13 |
| 39 | g10514.t1 | SMART | SM00441 | FF_2 | 561 | 615 | 1.8E-5 |
| 36 | g10514.t1 | SMART | SM00441 | FF_2 | 628 | 683 | 5.6E-7 |
| 38 | g10514.t1 | SMART | SM00441 | FF_2 | 828 | 884 | 6.3E-9 |
| 34 | g10514.t1 | SMART | SM00441 | FF_2 | 886 | 941 | 1.3E-11 |
| 35 | g10514.t1 | SMART | SM00441 | FF_2 | 943 | 1008 | 0.0089 |
| 11 | g10514.t1 | SUPERFAMILY | SSF51045 | WW domain | 92 | 132 | 1.26E-8 |
| 9 | g10514.t1 | SUPERFAMILY | SSF51045 | WW domain | 236 | 266 | 1.63E-8 |
| 10 | g10514.t1 | SUPERFAMILY | SSF51045 | WW domain | 347 | 383 | 8.16E-8 |
| 16 | g10514.t1 | SUPERFAMILY | SSF81698 | FF domain | 489 | 554 | 2.49E-15 |
| 13 | g10514.t1 | SUPERFAMILY | SSF81698 | FF domain | 555 | 622 | 2.62E-14 |
| 14 | g10514.t1 | SUPERFAMILY | SSF81698 | FF domain | 621 | 689 | 4.19E-14 |
| 15 | g10514.t1 | SUPERFAMILY | SSF81698 | FF domain | 820 | 891 | 5.36E-15 |
| 12 | g10514.t1 | SUPERFAMILY | SSF81698 | FF domain | 887 | 941 | 2.88E-11 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K12824 (transcription elongation regulator 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
