General information for g10647.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Palmitoyl-protein thioesterase 1.
Parent gene
- The parent gene g10647 is located on chr_1: 11101138..11103461 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10647 | g10647.t1 | isoform | g10647.t1 | 11100185 | 11101138 |
| chr_1 | g10647 | g10647.t1 | exon | g10647.t1.exon1 | 11100185 | 11100507 |
| chr_1 | g10647 | g10647.t1 | cds | g10647.t1.CDS1 | 11100185 | 11100507 |
| chr_1 | g10647 | g10647.t1 | exon | g10647.t1.exon2 | 11100574 | 11101138 |
| chr_1 | g10647 | g10647.t1 | cds | g10647.t1.CDS2 | 11100574 | 11101138 |
| chr_1 | g10647 | g10647.t1 | TSS | g10647.t1 | NA | NA |
| chr_1 | g10647 | g10647.t1 | TTS | g10647.t1 | NA | NA |
Sequences
>g10647.t1 Gene=g10647 Length=888
ATGTTGTGGCTTAAGTTATCCCAAATATTCACATTTTCGTGCATTTTTTTCGTGGTTTCT
GCAAATCTTCCAGTTTTAATATGGCATGGCCTCTTGAGTGATCCGCGAAATAATTTTAAC
TATTTCAAGCAAATGATGAAAGACGAGGCCAATGTTACGGTTAAGTCTGTCGATCTTACA
GTGAATAATTTGCACGAACGAGAAGTAAGTGTTTCAGTTCATCTATTCAACCAAATTGAT
CAAGTGTGTTACGAGATAAAAAAAGATGAGGAATTGAAAAATGGCTTCAATGCAATCGGA
TTGAGTCAAGGTGGTCAATTTATGCGAGGACTCATACAGCGATGTGATGCAGTAAAAGTA
AAAAATTTCATATCATTTGGAGGACAGCATCAAGGGATTTTTGGTCTTCCAAATTGCTCT
ATATCTAGCTCAATGTCACCCTGTAATCTGCTCAGAAAACTTCTCAATGTTTTTGCTTAC
ACAGATTGGGCACAAATGCATATCGCACAAACAACATACTGGCATGATCCGATCAGTCGA
AAGTATCAAAAATACAACACATTCATTGCTGATATTAACAATGAGCGTGATATCAATATG
GATTACATTCATCGATTGCAGCAACTCAATAAATTTGTACTCATAAAATTCCTACGAGAT
GAAATGGTTCAACCGATTGAGACACAATGGTTTGGATTTTATAAACCTGGCTCCGACAGG
ATTGTACAAAATATGACAGAAACAGCGACATATATAGAGGATAAGCTGGGATTGAGAAAA
ATGATGGAAAGCAGAAAGATAATATTTTTGGCAATCGATGATGAACATCTCAATATTGCA
ACTGAATGGTTTAGAGAGCATATTATACCATTGTTAAAAGACAATTAA
>g10647.t1 Gene=g10647 Length=295
MLWLKLSQIFTFSCIFFVVSANLPVLIWHGLLSDPRNNFNYFKQMMKDEANVTVKSVDLT
VNNLHEREVSVSVHLFNQIDQVCYEIKKDEELKNGFNAIGLSQGGQFMRGLIQRCDAVKV
KNFISFGGQHQGIFGLPNCSISSSMSPCNLLRKLLNVFAYTDWAQMHIAQTTYWHDPISR
KYQKYNTFIADINNERDINMDYIHRLQQLNKFVLIKFLRDEMVQPIETQWFGFYKPGSDR
IVQNMTETATYIEDKLGLRKMMESRKIIFLAIDDEHLNIATEWFREHIIPLLKDN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g10647.t1 | Gene3D | G3DSA:3.40.50.1820 | - | 18 | 295 | 1.2E-90 |
| 2 | g10647.t1 | PANTHER | PTHR11247 | PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 | 20 | 292 | 2.0E-78 |
| 3 | g10647.t1 | PANTHER | PTHR11247:SF8 | PALMITOYL-PROTEIN THIOESTERASE 1 | 20 | 292 | 2.0E-78 |
| 6 | g10647.t1 | PRINTS | PR00414 | Palmitoyl protein thioesterase signature | 16 | 38 | 1.7E-21 |
| 5 | g10647.t1 | PRINTS | PR00414 | Palmitoyl protein thioesterase signature | 93 | 109 | 1.7E-21 |
| 4 | g10647.t1 | PRINTS | PR00414 | Palmitoyl protein thioesterase signature | 139 | 158 | 1.7E-21 |
| 8 | g10647.t1 | PRINTS | PR00414 | Palmitoyl protein thioesterase signature | 173 | 192 | 1.7E-21 |
| 9 | g10647.t1 | PRINTS | PR00414 | Palmitoyl protein thioesterase signature | 224 | 242 | 1.7E-21 |
| 7 | g10647.t1 | PRINTS | PR00414 | Palmitoyl protein thioesterase signature | 269 | 287 | 1.7E-21 |
| 1 | g10647.t1 | Pfam | PF02089 | Palmitoyl protein thioesterase | 24 | 276 | 5.2E-71 |
| 14 | g10647.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 5 | - |
| 15 | g10647.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 6 | 28 | - |
| 13 | g10647.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 29 | 295 | - |
| 11 | g10647.t1 | SUPERFAMILY | SSF53474 | alpha/beta-Hydrolases | 21 | 292 | 6.48E-65 |
| 10 | g10647.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 9 | 31 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0098599 | palmitoyl hydrolase activity | MF |
| GO:0008474 | palmitoyl-(protein) hydrolase activity | MF |
| GO:0002084 | protein depalmitoylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed