General information for g10671.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Relaxin receptor 1.
Parent gene
- The parent gene g10671 is located on chr_1: 11271838..11275065 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10671 | g10671.t1 | isoform | g10671.t1 | 11271838 | 11275065 |
| chr_1 | g10671 | g10671.t1 | exon | g10671.t1.exon1 | 11271838 | 11271928 |
| chr_1 | g10671 | g10671.t1 | cds | g10671.t1.CDS1 | 11271838 | 11271928 |
| chr_1 | g10671 | g10671.t1 | exon | g10671.t1.exon2 | 11272142 | 11272230 |
| chr_1 | g10671 | g10671.t1 | cds | g10671.t1.CDS2 | 11272142 | 11272230 |
| chr_1 | g10671 | g10671.t1 | exon | g10671.t1.exon3 | 11272296 | 11272443 |
| chr_1 | g10671 | g10671.t1 | cds | g10671.t1.CDS3 | 11272296 | 11272443 |
| chr_1 | g10671 | g10671.t1 | exon | g10671.t1.exon4 | 11272508 | 11272605 |
| chr_1 | g10671 | g10671.t1 | cds | g10671.t1.CDS4 | 11272508 | 11272605 |
| chr_1 | g10671 | g10671.t1 | exon | g10671.t1.exon5 | 11272686 | 11272768 |
| chr_1 | g10671 | g10671.t1 | cds | g10671.t1.CDS5 | 11272686 | 11272768 |
| chr_1 | g10671 | g10671.t1 | exon | g10671.t1.exon6 | 11272826 | 11272897 |
| chr_1 | g10671 | g10671.t1 | cds | g10671.t1.CDS6 | 11272826 | 11272897 |
| chr_1 | g10671 | g10671.t1 | exon | g10671.t1.exon7 | 11272966 | 11273181 |
| chr_1 | g10671 | g10671.t1 | cds | g10671.t1.CDS7 | 11272966 | 11273181 |
| chr_1 | g10671 | g10671.t1 | exon | g10671.t1.exon8 | 11273238 | 11273309 |
| chr_1 | g10671 | g10671.t1 | cds | g10671.t1.CDS8 | 11273238 | 11273309 |
| chr_1 | g10671 | g10671.t1 | exon | g10671.t1.exon9 | 11273371 | 11273442 |
| chr_1 | g10671 | g10671.t1 | cds | g10671.t1.CDS9 | 11273371 | 11273442 |
| chr_1 | g10671 | g10671.t1 | exon | g10671.t1.exon10 | 11273503 | 11273574 |
| chr_1 | g10671 | g10671.t1 | cds | g10671.t1.CDS10 | 11273503 | 11273574 |
| chr_1 | g10671 | g10671.t1 | exon | g10671.t1.exon11 | 11273638 | 11273703 |
| chr_1 | g10671 | g10671.t1 | cds | g10671.t1.CDS11 | 11273638 | 11273703 |
| chr_1 | g10671 | g10671.t1 | exon | g10671.t1.exon12 | 11273763 | 11273902 |
| chr_1 | g10671 | g10671.t1 | cds | g10671.t1.CDS12 | 11273763 | 11273902 |
| chr_1 | g10671 | g10671.t1 | exon | g10671.t1.exon13 | 11273982 | 11274663 |
| chr_1 | g10671 | g10671.t1 | cds | g10671.t1.CDS13 | 11273982 | 11274663 |
| chr_1 | g10671 | g10671.t1 | exon | g10671.t1.exon14 | 11274738 | 11275065 |
| chr_1 | g10671 | g10671.t1 | cds | g10671.t1.CDS14 | 11274738 | 11275065 |
| chr_1 | g10671 | g10671.t1 | TSS | g10671.t1 | NA | NA |
| chr_1 | g10671 | g10671.t1 | TTS | g10671.t1 | NA | NA |
Sequences
>g10671.t1 Gene=g10671 Length=2229
ATGACATCGTTTAAAAAGAGTGTAATAATAGGAATTGTATTTTTTGGAATAATTTTATTA
ACAGCTCTTACAGTATTTTATATTTCATTGGGTGAATGTGAAGTTGGATTTTTTGCTTGT
GATAATGGTACAATCTGTTTACCACAAAAACTTGTGTGTGATTTTAAACCAGATTGTAAA
GATAAAACAGATGAAGTTCCTAGATTATGTGGAAATTTATATGGATCGAATGTGGTAACA
TCAAATGATCTCAAAATTGGCATTAATAGATATGTCTATCTTAAGAAAATATATAATTTT
ACTGATAAATCTTATATGGATACTTGTGCTTATAAAATAAAAAAGATTCCGAAAAATTGC
AAATGCCTGCGAGTACAATTGATATCATGCAAAAACATCTCAACTATCCCAAAATTCCCT
TCACACATTGAAATGATTGATTTATCAGATAATCATATTGCACTAGATTCTTACAACAGA
TTTGGCATTTACCGAAATTTGTCCTATTTGGATTTGAGAAACAATAAAATTCATCATTTA
CCATCACAAGTCTTCTATAAAGCAAACAATCTAGCCAAATTATTTCTACAAAATAACAGA
ATTACGGATTTGCCCTCTGGTTTTTCGAAGCATTTAATAGCACTTCGCTGGTTATTCTTA
AATAATAATCATCTTGGGGACTTTGCTCTCCGTAAATTTAAACATTTGCAAAATCTTCAG
ATGCTGAACCTCTCAATCAATTGCATCACGTTATCAAAAAACATGACATTTCCGAAGCTT
CCGCATCTTTATGAACTTTTTCTTGATGGAAATAAAATTAAAGTTCTAAGAGATAATCAT
TTTAAGAATCTCATAAATCTCAATTTAATATCATTGCGAAATAATCAAATAACTTTTATA
AATTCATCAGTATTTAATAGTTTACAATTCCTAATTGAAATACGACTCTCGGGAAATCCT
TTAATTAATATTGAACAAAATACATTTAAACATTTACAAAAATTAAATGCACTCTATTTA
GATTATACAAATGTTTTAATTGATGATGCTCTTTTATCAACTATCAATGTTTCATTTCTA
AGTTTAAAAGGGATTGCTAAAGAAAAAATTGAATTTAATGCCATTGAGAGAGTGCAAAAA
TTAGAGCATATTGTTTATAAAAAATTTTCGTACTGCTCTAGAACATCGAAAATTAAAAAA
TGTTATCCAAAAACAGATGGAATTTCTTCAACCTCTGACTTGTTGGACAATGTAGCACTT
CGTTATGCTGTGTGGTTCATGGCATGTATATCATGCATCGGAAACATTTCTGTACTTTGG
AATAGATTTCATGATGAAAATAAGAGTGTGAGCTTGGTCTTACGCAACTTGGCTATTTCT
GATATTATGATGGGATTCTATTTAATTGGAATTGGTTTCACAGATGCAAGATTCCGTAAT
GTTTATCATAAAAACTCTGGGACGTGGTTGCAGTCTATTGAATGCATTGCTTTAGGAATA
TTGGCAGTCACTTCTTCTGAAGTATCAATACTTATACTAACATTCATGTCAATAGAAAGA
TTCTTATTGATCTCTGACCCCTTTGGACATCACAAAATGGATACTAAAATTATTATAACT
AGCTTAATAGTCATTTGGATGCTAGGAACTATGATAGCAATTATACCAGCTATAATGTTT
CAATCTACAAAATTCTATGGTGTTTATAGCAGTGGCACATGTTTTCCACTTTTTATAGAG
GAAATATATTCAACTGCATGGATTTATTCTATTGTGTTCCTAGGGATTAATTTAATCTTA
CTTATTTTAATCGCCACACTCTATACGATCCTTTTATTTTCCATTTACCGAACGCGTCGA
GCAACGAGTTTAAACTACTTTGATTGTGAAGTGGCTATAAGATTCTTTTTCATAGTTCTC
ACAGACATCTCATGCTGGGCACCGATAATATTAATGAAATTATTCGTACTTTATGATATA
GAAATCTCAGGAGATGTTTATTCATATTTATGCATTTTTGTCTTGCCATTAAATGCCACA
ACTAATCCAATTTTATACACTTATTCAACACCTAAATATCGAGATAAAATATTTTCTATT
TTTAAGAAACAACGTAAAATCGATGTAAATTCTAATCAAATAATAACTGCAGACGATTCA
CAAACAAAAGTCAGTCTTTTACTATCAAATTCAAAAAATTCCTCAAAATGGAAACTTTTT
AAAAAATAA
>g10671.t1 Gene=g10671 Length=742
MTSFKKSVIIGIVFFGIILLTALTVFYISLGECEVGFFACDNGTICLPQKLVCDFKPDCK
DKTDEVPRLCGNLYGSNVVTSNDLKIGINRYVYLKKIYNFTDKSYMDTCAYKIKKIPKNC
KCLRVQLISCKNISTIPKFPSHIEMIDLSDNHIALDSYNRFGIYRNLSYLDLRNNKIHHL
PSQVFYKANNLAKLFLQNNRITDLPSGFSKHLIALRWLFLNNNHLGDFALRKFKHLQNLQ
MLNLSINCITLSKNMTFPKLPHLYELFLDGNKIKVLRDNHFKNLINLNLISLRNNQITFI
NSSVFNSLQFLIEIRLSGNPLINIEQNTFKHLQKLNALYLDYTNVLIDDALLSTINVSFL
SLKGIAKEKIEFNAIERVQKLEHIVYKKFSYCSRTSKIKKCYPKTDGISSTSDLLDNVAL
RYAVWFMACISCIGNISVLWNRFHDENKSVSLVLRNLAISDIMMGFYLIGIGFTDARFRN
VYHKNSGTWLQSIECIALGILAVTSSEVSILILTFMSIERFLLISDPFGHHKMDTKIIIT
SLIVIWMLGTMIAIIPAIMFQSTKFYGVYSSGTCFPLFIEEIYSTAWIYSIVFLGINLIL
LILIATLYTILLFSIYRTRRATSLNYFDCEVAIRFFFIVLTDISCWAPIILMKLFVLYDI
EISGDVYSYLCIFVLPLNATTNPILYTYSTPKYRDKIFSIFKKQRKIDVNSNQIITADDS
QTKVSLLLSNSKNSSKWKLFKK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 41 | g10671.t1 | CDD | cd00112 | LDLa | 33 | 65 | 5.95272E-9 |
| 23 | g10671.t1 | Gene3D | G3DSA:4.10.400.10 | - | 30 | 73 | 9.0E-10 |
| 21 | g10671.t1 | Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 76 | 251 | 3.3E-23 |
| 22 | g10671.t1 | Gene3D | G3DSA:3.80.10.10 | Ribonuclease Inhibitor | 252 | 406 | 3.5E-16 |
| 20 | g10671.t1 | Gene3D | G3DSA:1.20.1070.10 | - | 407 | 711 | 1.2E-37 |
| 5 | g10671.t1 | PANTHER | PTHR24372:SF72 | RELAXIN RECEPTOR 2 | 20 | 709 | 2.9E-127 |
| 6 | g10671.t1 | PANTHER | PTHR24372 | GLYCOPROTEIN HORMONE RECEPTOR | 20 | 709 | 2.9E-127 |
| 15 | g10671.t1 | PRINTS | PR01739 | Relaxin receptor family signature | 36 | 48 | 6.3E-14 |
| 11 | g10671.t1 | PRINTS | PR01739 | Relaxin receptor family signature | 194 | 209 | 6.3E-14 |
| 14 | g10671.t1 | PRINTS | PR01739 | Relaxin receptor family signature | 380 | 392 | 6.3E-14 |
| 16 | g10671.t1 | PRINTS | PR01739 | Relaxin receptor family signature | 396 | 410 | 6.3E-14 |
| 9 | g10671.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 450 | 471 | 2.7E-12 |
| 13 | g10671.t1 | PRINTS | PR01739 | Relaxin receptor family signature | 472 | 482 | 6.3E-14 |
| 7 | g10671.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 502 | 524 | 2.7E-12 |
| 8 | g10671.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 631 | 655 | 2.7E-12 |
| 12 | g10671.t1 | PRINTS | PR01739 | Relaxin receptor family signature | 655 | 669 | 6.3E-14 |
| 10 | g10671.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 668 | 694 | 2.7E-12 |
| 3 | g10671.t1 | Pfam | PF00057 | Low-density lipoprotein receptor domain class A | 32 | 65 | 4.4E-7 |
| 2 | g10671.t1 | Pfam | PF13855 | Leucine rich repeat | 165 | 225 | 6.3E-11 |
| 1 | g10671.t1 | Pfam | PF13855 | Leucine rich repeat | 261 | 321 | 3.7E-10 |
| 4 | g10671.t1 | Pfam | PF00001 | 7 transmembrane receptor (rhodopsin family) | 448 | 686 | 1.2E-17 |
| 25 | g10671.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 6 | - |
| 33 | g10671.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 7 | 30 | - |
| 32 | g10671.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 31 | 421 | - |
| 35 | g10671.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 422 | 440 | - |
| 26 | g10671.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 441 | 451 | - |
| 39 | g10671.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 452 | 469 | - |
| 30 | g10671.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 470 | 488 | - |
| 34 | g10671.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 489 | 516 | - |
| 27 | g10671.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 517 | 536 | - |
| 37 | g10671.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 537 | 560 | - |
| 31 | g10671.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 561 | 585 | - |
| 36 | g10671.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 586 | 614 | - |
| 28 | g10671.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 615 | 634 | - |
| 40 | g10671.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 635 | 660 | - |
| 29 | g10671.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 661 | 665 | - |
| 38 | g10671.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 666 | 688 | - |
| 24 | g10671.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 689 | 742 | - |
| 59 | g10671.t1 | ProSitePatterns | PS01209 | LDL-receptor class A (LDLRA) domain signature. | 46 | 70 | - |
| 58 | g10671.t1 | ProSitePatterns | PS00237 | G-protein coupled receptors family 1 signature. | 508 | 524 | - |
| 69 | g10671.t1 | ProSiteProfiles | PS50068 | LDL-receptor class A (LDLRA) domain profile. | 32 | 71 | 10.688 |
| 67 | g10671.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 142 | 162 | 4.67 |
| 66 | g10671.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 166 | 187 | 8.236 |
| 63 | g10671.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 190 | 211 | 7.481 |
| 60 | g10671.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 214 | 234 | 5.44 |
| 62 | g10671.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 238 | 259 | 5.756 |
| 61 | g10671.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 262 | 283 | 6.118 |
| 65 | g10671.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 286 | 307 | 6.164 |
| 64 | g10671.t1 | ProSiteProfiles | PS51450 | Leucine-rich repeat profile. | 310 | 331 | 5.063 |
| 68 | g10671.t1 | ProSiteProfiles | PS50262 | G-protein coupled receptors family 1 profile. | 431 | 686 | 25.527 |
| 50 | g10671.t1 | SMART | SM00192 | LDLa_2 | 32 | 72 | 7.0E-9 |
| 51 | g10671.t1 | SMART | SM00369 | LRR_typ_2 | 164 | 187 | 0.85 |
| 55 | g10671.t1 | SMART | SM00369 | LRR_typ_2 | 190 | 211 | 26.0 |
| 54 | g10671.t1 | SMART | SM00369 | LRR_typ_2 | 212 | 235 | 60.0 |
| 57 | g10671.t1 | SMART | SM00369 | LRR_typ_2 | 236 | 259 | 69.0 |
| 56 | g10671.t1 | SMART | SM00369 | LRR_typ_2 | 260 | 283 | 2.2 |
| 52 | g10671.t1 | SMART | SM00369 | LRR_typ_2 | 284 | 307 | 7.6 |
| 53 | g10671.t1 | SMART | SM00369 | LRR_typ_2 | 308 | 331 | 21.0 |
| 17 | g10671.t1 | SUPERFAMILY | SSF57424 | LDL receptor-like module | 28 | 68 | 1.96E-8 |
| 19 | g10671.t1 | SUPERFAMILY | SSF52058 | L domain-like | 118 | 344 | 1.13E-36 |
| 18 | g10671.t1 | SUPERFAMILY | SSF81321 | Family A G protein-coupled receptor-like | 416 | 709 | 6.68E-36 |
| 46 | g10671.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 7 | 29 | - |
| 49 | g10671.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 418 | 440 | - |
| 47 | g10671.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 452 | 474 | - |
| 42 | g10671.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 496 | 518 | - |
| 45 | g10671.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 538 | 560 | - |
| 44 | g10671.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 591 | 613 | - |
| 43 | g10671.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 634 | 656 | - |
| 48 | g10671.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 666 | 688 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0007186 | G protein-coupled receptor signaling pathway | BP |
| GO:0007165 | signal transduction | BP |
| GO:0005515 | protein binding | MF |
| GO:0016021 | integral component of membrane | CC |
| GO:0004930 | G protein-coupled receptor activity | MF |
KEGG
Orthology
- This transcript has been annotated with K04307 (relaxin family peptide receptor 2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
