General information for g10691.t5
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as AP-2 complex subunit mu.
Parent gene
- The parent gene g10691 is located on chr_1: 11338501..11339776 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10691 | g10691.t5 | TSS | g10691.t5 | 11337279 | 11337279 |
| chr_1 | g10691 | g10691.t5 | isoform | g10691.t5 | 11337383 | 11339776 |
| chr_1 | g10691 | g10691.t5 | exon | g10691.t5.exon1 | 11337383 | 11337386 |
| chr_1 | g10691 | g10691.t5 | exon | g10691.t5.exon2 | 11337640 | 11337876 |
| chr_1 | g10691 | g10691.t5 | cds | g10691.t5.CDS1 | 11337700 | 11337876 |
| chr_1 | g10691 | g10691.t5 | exon | g10691.t5.exon3 | 11337943 | 11338105 |
| chr_1 | g10691 | g10691.t5 | cds | g10691.t5.CDS2 | 11337943 | 11338105 |
| chr_1 | g10691 | g10691.t5 | exon | g10691.t5.exon4 | 11338163 | 11338438 |
| chr_1 | g10691 | g10691.t5 | cds | g10691.t5.CDS3 | 11338163 | 11338438 |
| chr_1 | g10691 | g10691.t5 | exon | g10691.t5.exon5 | 11338495 | 11339087 |
| chr_1 | g10691 | g10691.t5 | cds | g10691.t5.CDS4 | 11338495 | 11339087 |
| chr_1 | g10691 | g10691.t5 | exon | g10691.t5.exon6 | 11339144 | 11339776 |
| chr_1 | g10691 | g10691.t5 | cds | g10691.t5.CDS5 | 11339144 | 11339251 |
| chr_1 | g10691 | g10691.t5 | TTS | g10691.t5 | NA | NA |
Sequences
>g10691.t5 Gene=g10691 Length=1906
ACAAAAATATCTTTTCCGGAAATTCGCAGAGCGAAAGAGAGGAAGGGAAATTTAAAGAGT
AAGGATGATTGGTGGATTATTCGTTTACAATCACAAAGGTGAAGTTCTAATATCTCGTGT
TTATCGCGATGATATTGGAAGAAATGCTGTTGACGCTTTTAGAGTAAATGTCATTCATGC
TCGTCAACAAGTTAGATCACCCGTGACAAACATCGCAAGAACAAGTTTTTTTCACATAAA
AAGAGCGAATATTTGGTTGGCTGCTGTAACCAAACAAAATGTAAATGCTGCAATGGTTTT
CGAATTTTTATTGAAAATCATTGATGTCATGCAATCTTACTTTGGAAAAATTTCCGAAGA
AAATATTAAAAATAATTTTGTCCTTATTTATGAACTTTTGGACGAAATTCTTGATTTTGG
TTACCCACAAAATTCTGATACTGGAGTTTTAAAGACATTTATAACGCAACAAGGTATTAA
ATCAGCAACAAAAGAAGAGCAGGCGCAAATAACATCTCAAGTCACTGGTCAAATTGGTTG
GCGTAGAGAAGGAATTAAATACAGACGCAATGAACTATTTTTGGATGTTTTGGAATATGT
TAATTTGCTCATGAGTCCCCAAGGACAAGTATTATCAGCTCATGTCGCTGGGAAAGTTGT
TATGAAATCATTTTTATCAGGTATGCCGGAATGTAAATTTGGTATTAATGATAAAATCGT
TATGGAAGCCAAGGGTCGTGGAGGTATATCTGGAAATACTGAAGCAGAAACATCACGATC
AGGCAAACCTGTAGTCGTTATTGATGATTGCCAATTTCATCAGTGCGTTAAATTGAGCAA
ATTTGAAACAGAACATTCTATAAGCTTCATTCCACCTGATGGTGAATTTGAATTGATGCG
TTATCGTACAACAAAAGATATATCATTGCCATTCCGTGTTATTCCATTGGTGCGTGAAGT
CGGTCGAACAAAAATGGAGGTCAAAGTTGTTTTAAAATCTAACTTCAAACCTTCACTACT
TGGGCAGAAGATTGAAGTGAAAATTCCAACACCACTCAATACATCTGGTGTGCAGCTTAT
TTGTTTGAAAGGAAAAGCCAAATATAAGGCTTCGGAGAACGCAATCGTTTGGAAAATTAA
AAGAATGGCTGGTATGAAGGAAACTCAATTATCAGCAGAAATTGAATTGCTAGAAACGGA
CACGAAGAAGAAATGGACTCGACCACCAATTTCGATGAACTTTGAAGTTCCATTTGCTCC
ATCTGGCTTTAAGGTTCGTTATTTGAAAGTTTTTGAACCTAAACTCAACTATTCTGATCA
TGATGTCATTAAATGGGTTCGCTATATTGGTCGAAGTGGGCTATATGAAACAAGATGCTA
AGTTGCTGCTATCTAATATTGATATTGAATCTTTTCTAATTGTTCTTTTGTTCTCTTGAG
CAATTATAATGTGACAAGAAATGACATTTAAATTATATATGAATATTGCATGTTTGAATA
TAGCAAATTTGCAAACAGTGTAGTAAAACAAAATTCTTTGCATGAAATATATACATTCAT
TACTATTATTATTCTGATTATTATTCTTTTAAGAATTTGAAAACATAATACTACATATAC
GTTAAAGATTTGCATGAAAATCTCCTATCTTAGATACATAAGGAAGCTATTGTATCGTAT
AAAATTTATTGCTTCATTAATCAAATAAAATAAATAATAGTAAATTGAAAATGTTTATAT
GATTTTTAAGTTAAAACTGAGGAAACTTAGAGATAATGCACTTTATATTTAGTGCTGAAC
ACATAATATTTATCGTTGCGGTACTTAAAATTGAACACTTAATACGGTGCGTCAAAATAA
TAAAAGAAATACTATTCAAGATTAAACGTTTCATAACACTAAAAAT
>g10691.t5 Gene=g10691 Length=438
MIGGLFVYNHKGEVLISRVYRDDIGRNAVDAFRVNVIHARQQVRSPVTNIARTSFFHIKR
ANIWLAAVTKQNVNAAMVFEFLLKIIDVMQSYFGKISEENIKNNFVLIYELLDEILDFGY
PQNSDTGVLKTFITQQGIKSATKEEQAQITSQVTGQIGWRREGIKYRRNELFLDVLEYVN
LLMSPQGQVLSAHVAGKVVMKSFLSGMPECKFGINDKIVMEAKGRGGISGNTEAETSRSG
KPVVVIDDCQFHQCVKLSKFETEHSISFIPPDGEFELMRYRTTKDISLPFRVIPLVREVG
RTKMEVKVVLKSNFKPSLLGQKIEVKIPTPLNTSGVQLICLKGKAKYKASENAIVWKIKR
MAGMKETQLSAEIELLETDTKKKWTRPPISMNFEVPFAPSGFKVRYLKVFEPKLNYSDHD
VIKWVRYIGRSGLYETRC
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 19 | g10691.t5 | CDD | cd14836 | AP2_Mu_N | 1 | 140 | 6.14045E-92 |
| 18 | g10691.t5 | CDD | cd09251 | AP-2_Mu2_Cterm | 166 | 437 | 6.98054E-173 |
| 13 | g10691.t5 | Gene3D | G3DSA:3.30.450.60 | - | 1 | 141 | 2.7E-58 |
| 15 | g10691.t5 | Gene3D | G3DSA:2.60.40.1170 | - | 164 | 241 | 1.9E-22 |
| 16 | g10691.t5 | Gene3D | G3DSA:2.60.40.1170 | - | 255 | 431 | 1.0E-84 |
| 14 | g10691.t5 | Gene3D | G3DSA:2.60.40.1170 | - | 288 | 438 | 1.0E-84 |
| 3 | g10691.t5 | PANTHER | PTHR10529 | AP COMPLEX SUBUNIT MU | 1 | 438 | 6.3E-187 |
| 4 | g10691.t5 | PANTHER | PTHR10529:SF236 | AP-2 COMPLEX SUBUNIT MU | 1 | 438 | 6.3E-187 |
| 17 | g10691.t5 | PIRSF | PIRSF005992 | AP_complex_mu | 1 | 438 | 7.4E-140 |
| 8 | g10691.t5 | PRINTS | PR00314 | Clathrin coat assembly protein signature | 12 | 32 | 1.2E-66 |
| 10 | g10691.t5 | PRINTS | PR00314 | Clathrin coat assembly protein signature | 98 | 125 | 1.2E-66 |
| 9 | g10691.t5 | PRINTS | PR00314 | Clathrin coat assembly protein signature | 159 | 187 | 1.2E-66 |
| 5 | g10691.t5 | PRINTS | PR00314 | Clathrin coat assembly protein signature | 246 | 273 | 1.2E-66 |
| 7 | g10691.t5 | PRINTS | PR00314 | Clathrin coat assembly protein signature | 315 | 330 | 1.2E-66 |
| 6 | g10691.t5 | PRINTS | PR00314 | Clathrin coat assembly protein signature | 355 | 366 | 1.2E-66 |
| 2 | g10691.t5 | Pfam | PF01217 | Clathrin adaptor complex small chain | 2 | 126 | 3.0E-6 |
| 1 | g10691.t5 | Pfam | PF00928 | Adaptor complexes medium subunit family | 158 | 438 | 3.2E-78 |
| 21 | g10691.t5 | ProSitePatterns | PS00990 | Clathrin adaptor complexes medium chain signature 1. | 157 | 177 | - |
| 20 | g10691.t5 | ProSitePatterns | PS00991 | Clathrin adaptor complexes medium chain signature 2. | 266 | 280 | - |
| 22 | g10691.t5 | ProSiteProfiles | PS51072 | Mu homology domain (MHD) profile. | 168 | 437 | 44.669 |
| 11 | g10691.t5 | SUPERFAMILY | SSF64356 | SNARE-like | 1 | 139 | 5.95E-42 |
| 12 | g10691.t5 | SUPERFAMILY | SSF49447 | Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 157 | 437 | 3.4E-89 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006886 | intracellular protein transport | BP |
| GO:0030131 | clathrin adaptor complex | CC |
| GO:0016192 | vesicle-mediated transport | BP |
KEGG
Orthology
- This transcript has been annotated with K11826 (AP-2 complex subunit mu-1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed