General information for g10691.t9
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as AP-2 complex subunit mu.
Parent gene
- The parent gene g10691 is located on chr_1: 11338501..11339776 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10691 | g10691.t9 | isoform | g10691.t9 | 11338501 | 11339776 |
| chr_1 | g10691 | g10691.t9 | exon | g10691.t9.exon1 | 11338501 | 11339087 |
| chr_1 | g10691 | g10691.t9 | cds | g10691.t9.CDS1 | 11338536 | 11339087 |
| chr_1 | g10691 | g10691.t9 | exon | g10691.t9.exon2 | 11339144 | 11339776 |
| chr_1 | g10691 | g10691.t9 | cds | g10691.t9.CDS2 | 11339144 | 11339251 |
| chr_1 | g10691 | g10691.t9 | TSS | g10691.t9 | NA | NA |
| chr_1 | g10691 | g10691.t9 | TTS | g10691.t9 | NA | NA |
Sequences
>g10691.t9 Gene=g10691 Length=1220
CGGAATGTAAATTTGGTATTAATGATAAAATCGTTATGGAAGCCAAGGGTCGTGGAGGTA
TATCTGGAAATACTGAAGCAGAAACATCACGATCAGGCAAACCTGTAGTCGTTATTGATG
ATTGCCAATTTCATCAGTGCGTTAAATTGAGCAAATTTGAAACAGAACATTCTATAAGCT
TCATTCCACCTGATGGTGAATTTGAATTGATGCGTTATCGTACAACAAAAGATATATCAT
TGCCATTCCGTGTTATTCCATTGGTGCGTGAAGTCGGTCGAACAAAAATGGAGGTCAAAG
TTGTTTTAAAATCTAACTTCAAACCTTCACTACTTGGGCAGAAGATTGAAGTGAAAATTC
CAACACCACTCAATACATCTGGTGTGCAGCTTATTTGTTTGAAAGGAAAAGCCAAATATA
AGGCTTCGGAGAACGCAATCGTTTGGAAAATTAAAAGAATGGCTGGTATGAAGGAAACTC
AATTATCAGCAGAAATTGAATTGCTAGAAACGGACACGAAGAAGAAATGGACTCGACCAC
CAATTTCGATGAACTTTGAAGTTCCATTTGCTCCATCTGGCTTTAAGGTTCGTTATTTGA
AAGTTTTTGAACCTAAACTCAACTATTCTGATCATGATGTCATTAAATGGGTTCGCTATA
TTGGTCGAAGTGGGCTATATGAAACAAGATGCTAAGTTGCTGCTATCTAATATTGATATT
GAATCTTTTCTAATTGTTCTTTTGTTCTCTTGAGCAATTATAATGTGACAAGAAATGACA
TTTAAATTATATATGAATATTGCATGTTTGAATATAGCAAATTTGCAAACAGTGTAGTAA
AACAAAATTCTTTGCATGAAATATATACATTCATTACTATTATTATTCTGATTATTATTC
TTTTAAGAATTTGAAAACATAATACTACATATACGTTAAAGATTTGCATGAAAATCTCCT
ATCTTAGATACATAAGGAAGCTATTGTATCGTATAAAATTTATTGCTTCATTAATCAAAT
AAAATAAATAATAGTAAATTGAAAATGTTTATATGATTTTTAAGTTAAAACTGAGGAAAC
TTAGAGATAATGCACTTTATATTTAGTGCTGAACACATAATATTTATCGTTGCGGTACTT
AAAATTGAACACTTAATACGGTGCGTCAAAATAATAAAAGAAATACTATTCAAGATTAAA
CGTTTCATAACACTAAAAAT
>g10691.t9 Gene=g10691 Length=219
MEAKGRGGISGNTEAETSRSGKPVVVIDDCQFHQCVKLSKFETEHSISFIPPDGEFELMR
YRTTKDISLPFRVIPLVREVGRTKMEVKVVLKSNFKPSLLGQKIEVKIPTPLNTSGVQLI
CLKGKAKYKASENAIVWKIKRMAGMKETQLSAEIELLETDTKKKWTRPPISMNFEVPFAP
SGFKVRYLKVFEPKLNYSDHDVIKWVRYIGRSGLYETRC
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g10691.t9 | CDD | cd09251 | AP-2_Mu2_Cterm | 10 | 218 | 1.50691E-130 |
| 10 | g10691.t9 | Coils | Coil | Coil | 216 | 219 | - |
| 9 | g10691.t9 | Gene3D | G3DSA:2.60.40.1170 | - | 36 | 212 | 1.4E-85 |
| 8 | g10691.t9 | Gene3D | G3DSA:2.60.40.1170 | - | 69 | 219 | 1.4E-85 |
| 13 | g10691.t9 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 20 | - |
| 2 | g10691.t9 | PANTHER | PTHR10529 | AP COMPLEX SUBUNIT MU | 18 | 219 | 2.8E-81 |
| 3 | g10691.t9 | PANTHER | PTHR10529:SF236 | AP-2 COMPLEX SUBUNIT MU | 18 | 219 | 2.8E-81 |
| 6 | g10691.t9 | PRINTS | PR00314 | Clathrin coat assembly protein signature | 27 | 54 | 3.1E-22 |
| 5 | g10691.t9 | PRINTS | PR00314 | Clathrin coat assembly protein signature | 96 | 111 | 3.1E-22 |
| 4 | g10691.t9 | PRINTS | PR00314 | Clathrin coat assembly protein signature | 136 | 147 | 3.1E-22 |
| 1 | g10691.t9 | Pfam | PF00928 | Adaptor complexes medium subunit family | 21 | 219 | 2.0E-53 |
| 12 | g10691.t9 | ProSitePatterns | PS00991 | Clathrin adaptor complexes medium chain signature 2. | 47 | 61 | - |
| 14 | g10691.t9 | ProSiteProfiles | PS51072 | Mu homology domain (MHD) profile. | 1 | 218 | 33.345 |
| 7 | g10691.t9 | SUPERFAMILY | SSF49447 | Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 17 | 218 | 1.24E-63 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006886 | intracellular protein transport | BP |
| GO:0030131 | clathrin adaptor complex | CC |
| GO:0016192 | vesicle-mediated transport | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
