General information for g10695.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Sodium-coupled monocarboxylate transporter 2.
Parent gene
- The parent gene g10695 is located on chr_1: 11402249..11403323 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10695 | g10695.t1 | TSS | g10695.t1 | 11400702 | 11400702 |
| chr_1 | g10695 | g10695.t1 | isoform | g10695.t1 | 11400726 | 11403323 |
| chr_1 | g10695 | g10695.t1 | exon | g10695.t1.exon1 | 11400726 | 11401035 |
| chr_1 | g10695 | g10695.t1 | cds | g10695.t1.CDS1 | 11400726 | 11401035 |
| chr_1 | g10695 | g10695.t1 | exon | g10695.t1.exon2 | 11401120 | 11401218 |
| chr_1 | g10695 | g10695.t1 | cds | g10695.t1.CDS2 | 11401120 | 11401218 |
| chr_1 | g10695 | g10695.t1 | exon | g10695.t1.exon3 | 11401364 | 11401398 |
| chr_1 | g10695 | g10695.t1 | cds | g10695.t1.CDS3 | 11401364 | 11401398 |
| chr_1 | g10695 | g10695.t1 | exon | g10695.t1.exon4 | 11401465 | 11401548 |
| chr_1 | g10695 | g10695.t1 | cds | g10695.t1.CDS4 | 11401465 | 11401548 |
| chr_1 | g10695 | g10695.t1 | exon | g10695.t1.exon5 | 11401609 | 11401641 |
| chr_1 | g10695 | g10695.t1 | cds | g10695.t1.CDS5 | 11401609 | 11401641 |
| chr_1 | g10695 | g10695.t1 | exon | g10695.t1.exon6 | 11401697 | 11401765 |
| chr_1 | g10695 | g10695.t1 | cds | g10695.t1.CDS6 | 11401697 | 11401765 |
| chr_1 | g10695 | g10695.t1 | exon | g10695.t1.exon7 | 11401833 | 11401863 |
| chr_1 | g10695 | g10695.t1 | cds | g10695.t1.CDS7 | 11401833 | 11401863 |
| chr_1 | g10695 | g10695.t1 | exon | g10695.t1.exon8 | 11402063 | 11402186 |
| chr_1 | g10695 | g10695.t1 | cds | g10695.t1.CDS8 | 11402063 | 11402186 |
| chr_1 | g10695 | g10695.t1 | exon | g10695.t1.exon9 | 11402249 | 11403323 |
| chr_1 | g10695 | g10695.t1 | cds | g10695.t1.CDS9 | 11402249 | 11403323 |
| chr_1 | g10695 | g10695.t1 | TTS | g10695.t1 | 11403411 | 11403411 |
Sequences
>g10695.t1 Gene=g10695 Length=1860
ATGACAACGGGAAGTGTAGAGGAAACTGTATCAGTCTCAAGCCGCAATGTAGAGGAGTTG
AGCGATTCTCTAAAAACCTTCGGTGCACTTGATTACGTCGTATTTGCTGCGATGCTTGTT
TGCTGTTCCGCTGTTGGTCTTTATTTTGGCTACCAGGATCATATGAAGCACAAGCGATCA
AGGAGAAATCGTCGTGGATCAATAATTGAGGTCGAAGCTATTGATTATCTCATGGGAGGA
AGAAACATGAAGGTCTTTCCCGTTGCCATGTCATTAGTTGCAAGTTTTGTATCAGGAATT
ACGCTACTTGGAACAAGTACAGAGATTTATTTGTATGGCACTCAATATTGCTACATCGCA
ATCGCTATAATACTATCAGCCTTGATTATGCATTTTACAATCATTCCAGTGTTTCATGAA
CTTCAAATTACGTCCACTTATGAGTATCTTCAGAGGCGCTTTGATAAAAATGTGCGGTTA
TTTGGATCAATTATGTTTTCACTCGCGACAATTCTGTGGCTTCCTATAGTCATTTATGTG
CCAGCCTTGGCCTTTAATCAGACGACAGGAATTAATATTCACATTATTACACCCTTGGTT
ATGTCCATTTGCATTTTTTATACATCACTGGGTGGCATTAAAGCTGTTGTATGGACTGAT
GTTATTCAAATGATTCTCATGTATGGAACACTCTTTCTGATTGTCATAAAAGGAACAATG
AACGTTGGCGGCTTGTCCGTTGTGATTGAAAGAAATGCGGCAAGCGGAAGATTTGAGGCG
CCTAACTTCGATTTCGATCCAACTGTTCGACATACATTCTGGACAATTGTAATCGGGGGA
ACAATATTTTGGGTGAACACAAATGGTCTAAATCAAAATATGATTCAACGCTATATGTCG
TTAAAAGACGTTCGTACAGCAAGAAAGGGACAGATGATGTATGTTATCGGAGTCAGTTTT
ATGATCTTTTTATGCTGCTTTAATGGACTATTGTTGTTCGCCACATACCATGACTGTGAT
CCACTCACCACGAAATTGGCCAAAGCAAAGGACCAACTGATGCCATTGTTGGTTATGGAA
ATATTGAAAGACATTCCTGGATTACCCGGATTATTTATAGCTGGTGTATTTTCTGCTGCA
CTTTCATCACTCTCAACTGGATTAAATTCAATGTCATGTGTCATTCTCGAAGATTTTTGT
AAGCCATTTGTAAAGAGAGAAATATCAGAGTCTATGAGTAGCTTAATCATGAGAGGAACT
GTATTAGTAATTGGACTGTTAGCTGTAGGATTGGTTTATGTTGTTCAACATTTAGGTTCA
GTATTGCAACTTTCAATGAGCATCCCAACTGCATGTTTTGGTCCAATGTTGGGTGTTTAT
GTCATTGGCTTTACTCTACCCTGGATTGGAAGAAGAGCTACTCTCTTCGCTGCAATGTTT
GCTTGCTTTTCAATGATGTGTCTTGTGTTTAAAGCTCAAGCAGAAATTGCACTTGGCAAC
ATTAACTTTGAAACGAAGCCTTTGACTACTGAGGGTTGCACGTACAATTTTACACTAACA
AGTACTCTCAATGCAACAGATGTCCCACATGAAGAGAATCATGAGAAACATATATGGAAC
ATTTCTTATTTATATTATGCTCCATTAGGTTCTTCCATCGTCATCATCACAGCTTTCCTC
CTAAGCTTCATCTTTGGCTTTCAAGACTCTAGTACTGTCGACTCTCGACTGCTTGCTCCA
TTTTTACGGAAATACATTAACTCAAATGAAAGCAGGAAGATTCAATATATGGATGCGAGT
GGAAAAGAGACTGTCATTCACAATTTTGAACTAAAAGAAGATAAGAACAATGTTACGTAG
>g10695.t1 Gene=g10695 Length=619
MTTGSVEETVSVSSRNVEELSDSLKTFGALDYVVFAAMLVCCSAVGLYFGYQDHMKHKRS
RRNRRGSIIEVEAIDYLMGGRNMKVFPVAMSLVASFVSGITLLGTSTEIYLYGTQYCYIA
IAIILSALIMHFTIIPVFHELQITSTYEYLQRRFDKNVRLFGSIMFSLATILWLPIVIYV
PALAFNQTTGINIHIITPLVMSICIFYTSLGGIKAVVWTDVIQMILMYGTLFLIVIKGTM
NVGGLSVVIERNAASGRFEAPNFDFDPTVRHTFWTIVIGGTIFWVNTNGLNQNMIQRYMS
LKDVRTARKGQMMYVIGVSFMIFLCCFNGLLLFATYHDCDPLTTKLAKAKDQLMPLLVME
ILKDIPGLPGLFIAGVFSAALSSLSTGLNSMSCVILEDFCKPFVKREISESMSSLIMRGT
VLVIGLLAVGLVYVVQHLGSVLQLSMSIPTACFGPMLGVYVIGFTLPWIGRRATLFAAMF
ACFSMMCLVFKAQAEIALGNINFETKPLTTEGCTYNFTLTSTLNATDVPHEENHEKHIWN
ISYLYYAPLGSSIVIITAFLLSFIFGFQDSSTVDSRLLAPFLRKYINSNESRKIQYMDAS
GKETVIHNFELKEDKNNVT
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 32 | g10695.t1 | CDD | cd11492 | SLC5sbd_NIS-SMVT | 31 | 564 | 0.0 |
| 4 | g10695.t1 | Gene3D | G3DSA:1.20.1730.10 | - | 67 | 576 | 8.7E-117 |
| 2 | g10695.t1 | PANTHER | PTHR42985 | SODIUM-COUPLED MONOCARBOXYLATE TRANSPORTER | 19 | 599 | 2.1E-245 |
| 3 | g10695.t1 | PANTHER | PTHR42985:SF5 | LP24461P | 19 | 599 | 2.1E-245 |
| 1 | g10695.t1 | Pfam | PF00474 | Sodium:solute symporter family | 76 | 459 | 9.1E-41 |
| 15 | g10695.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 31 | - |
| 21 | g10695.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 32 | 51 | - |
| 10 | g10695.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 52 | 84 | - |
| 27 | g10695.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 85 | 106 | - |
| 18 | g10695.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 107 | 117 | - |
| 19 | g10695.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 118 | 139 | - |
| 9 | g10695.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 140 | 159 | - |
| 25 | g10695.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 160 | 185 | - |
| 16 | g10695.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 186 | 190 | - |
| 23 | g10695.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 191 | 213 | - |
| 5 | g10695.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 214 | 224 | - |
| 22 | g10695.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 225 | 249 | - |
| 17 | g10695.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 250 | 268 | - |
| 20 | g10695.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 269 | 291 | - |
| 8 | g10695.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 292 | 311 | - |
| 30 | g10695.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 312 | 336 | - |
| 14 | g10695.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 337 | 370 | - |
| 31 | g10695.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 371 | 395 | - |
| 11 | g10695.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 396 | 414 | - |
| 28 | g10695.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 415 | 435 | - |
| 13 | g10695.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 436 | 440 | - |
| 29 | g10695.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 441 | 463 | - |
| 7 | g10695.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 464 | 474 | - |
| 26 | g10695.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 475 | 494 | - |
| 12 | g10695.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 495 | 542 | - |
| 24 | g10695.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 543 | 567 | - |
| 6 | g10695.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 568 | 619 | - |
| 46 | g10695.t1 | ProSiteProfiles | PS50283 | Sodium:solute symporter family profile. | 28 | 495 | 48.914 |
| 47 | g10695.t1 | TIGRFAM | TIGR00813 | sss: transporter, solute:sodium symporter (SSS) family | 76 | 475 | 1.3E-85 |
| 42 | g10695.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 29 | 51 | - |
| 41 | g10695.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 85 | 107 | - |
| 34 | g10695.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 117 | 139 | - |
| 40 | g10695.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 159 | 181 | - |
| 37 | g10695.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 191 | 213 | - |
| 43 | g10695.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 226 | 248 | - |
| 45 | g10695.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 268 | 290 | - |
| 36 | g10695.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 314 | 336 | - |
| 39 | g10695.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 371 | 393 | - |
| 38 | g10695.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 414 | 436 | - |
| 33 | g10695.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 446 | 468 | - |
| 35 | g10695.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 475 | 497 | - |
| 44 | g10695.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 545 | 567 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0055085 | transmembrane transport | BP |
| GO:0022857 | transmembrane transporter activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed