General information for g10749.t13
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as ATP-dependent 6-phosphofructokinase.
Parent gene
- The parent gene g10749 is located on chr_1: 11703097..11706214 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10749 | g10749.t13 | isoform | g10749.t13 | 11699680 | 11703097 |
| chr_1 | g10749 | g10749.t13 | exon | g10749.t13.exon1 | 11699680 | 11699686 |
| chr_1 | g10749 | g10749.t13 | exon | g10749.t13.exon2 | 11701464 | 11701572 |
| chr_1 | g10749 | g10749.t13 | exon | g10749.t13.exon3 | 11702119 | 11702253 |
| chr_1 | g10749 | g10749.t13 | exon | g10749.t13.exon4 | 11702336 | 11702371 |
| chr_1 | g10749 | g10749.t13 | exon | g10749.t13.exon5 | 11702510 | 11703097 |
| chr_1 | g10749 | g10749.t13 | cds | g10749.t13.CDS1 | 11702610 | 11703095 |
| chr_1 | g10749 | g10749.t13 | TSS | g10749.t13 | NA | NA |
| chr_1 | g10749 | g10749.t13 | TTS | g10749.t13 | NA | NA |
Sequences
>g10749.t13 Gene=g10749 Length=875
ACTGTGGTTACTTAGCTGTAGTCGCTGCGCTTGCTTCAGAAGCTGACTACGTATTTATAC
CTGAGGATCCTGTCAACGTTCACTGGAAAGAGAATCTGTGCAAAAAATTACTTCAGGAAC
GTTCTGCTGGTCAGCGTTTAAACATTATAATTGTTGCTGAAGGAGCTATTGATCGTGAAG
GTAATCCTATTACAGCTGAAATGGTTAAGAAAGTAGTCGTTGATGAATTGAAACAAGACA
CAAGAATCACTAGAGGAGGAAATCCTTCAGCTTTCGATCGTGTTTTGCATGGGCGCAGAA
GCTGTTATGGCTTTGATGGAAGCAACAGATGACACTGAACCTTGTGTCGTTTCATTAGAC
GGCAATCAAGCTGTTCGTCTCCCACTTATGGAATGTGTTAATCGCACACAAGCTGTAGCT
AAAGCCATGGCTGAACGTAAATTTGAATTAGCTGTTGACCTTCGTGGACGTTCATTTGCA
AGAAATTTAGAGACATACAAAATGTTGACTCGCTTGAAGCCACCAAAAGAAGCTTTTGAT
GCTGAAGGTCGTGGAAAAGAAGGGTACACTCTTGCTGTTATGCATATCGGTGCACCAGCT
TGTGGAATGAATGCAGCAGTTCGTTCATTTGTTCGTAATTCAATTTATCGAGGTGATACT
GTTTATGGTATTCACGACGGAATTGAAGGATTGGTTGCAGGACATTTTACAAAAATGGAT
TGGGCTGATGTCACTGGCTGGGTTGGACAAGGTGGTGCTTTTCTTGGAACAAAACGTACA
CTTCCAGAAGGAAAGTTCAAGGAAATCGCTCAAAGATTCCGTGAATTTGGTATTCAAGGT
TTGCTTGTCGTTGGTGGTTTCGAAGGCTATCATTC
>g10749.t13 Gene=g10749 Length=162
MECVNRTQAVAKAMAERKFELAVDLRGRSFARNLETYKMLTRLKPPKEAFDAEGRGKEGY
TLAVMHIGAPACGMNAAVRSFVRNSIYRGDTVYGIHDGIEGLVAGHFTKMDWADVTGWVG
QGGAFLGTKRTLPEGKFKEIAQRFREFGIQGLLVVGGFEGYH
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g10749.t13 | Coils | Coil | Coil | 161 | 162 | - |
| 8 | g10749.t13 | Gene3D | G3DSA:3.40.50.450 | - | 1 | 13 | 2.5E-6 |
| 7 | g10749.t13 | Gene3D | G3DSA:3.40.50.460 | - | 14 | 38 | 2.5E-6 |
| 9 | g10749.t13 | Gene3D | G3DSA:3.40.50.450 | - | 62 | 162 | 3.5E-41 |
| 2 | g10749.t13 | PANTHER | PTHR13697 | PHOSPHOFRUCTOKINASE | 1 | 162 | 1.1E-57 |
| 5 | g10749.t13 | PRINTS | PR00476 | ATP-dependent phosphofructokinase family signature | 64 | 83 | 8.9E-12 |
| 3 | g10749.t13 | PRINTS | PR00476 | ATP-dependent phosphofructokinase family signature | 89 | 102 | 8.9E-12 |
| 4 | g10749.t13 | PRINTS | PR00476 | ATP-dependent phosphofructokinase family signature | 148 | 162 | 8.9E-12 |
| 1 | g10749.t13 | Pfam | PF00365 | Phosphofructokinase | 62 | 161 | 2.7E-28 |
| 6 | g10749.t13 | SUPERFAMILY | SSF53784 | Phosphofructokinase | 1 | 161 | 2.35E-35 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0003872 | 6-phosphofructokinase activity | MF |
| GO:0006002 | fructose 6-phosphate metabolic process | BP |
| GO:0006096 | glycolytic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
