General information for g10749.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as ATP-dependent 6-phosphofructokinase.
Parent gene
- The parent gene g10749 is located on chr_1: 11703097..11706214 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10749 | g10749.t3 | TSS | g10749.t3 | 11697838 | 11697838 |
| chr_1 | g10749 | g10749.t3 | isoform | g10749.t3 | 11697983 | 11699680 |
| chr_1 | g10749 | g10749.t3 | exon | g10749.t3.exon1 | 11697983 | 11698095 |
| chr_1 | g10749 | g10749.t3 | exon | g10749.t3.exon2 | 11698221 | 11698385 |
| chr_1 | g10749 | g10749.t3 | exon | g10749.t3.exon3 | 11699218 | 11699680 |
| chr_1 | g10749 | g10749.t3 | cds | g10749.t3.CDS1 | 11699220 | 11699678 |
| chr_1 | g10749 | g10749.t3 | TTS | g10749.t3 | NA | NA |
Sequences
>g10749.t3 Gene=g10749 Length=741
TTGCTTTTTTTCTAGTTCAGGAAGAAAATAGAAAAAAAAGTTTAGGTCAACAAAAATTAA
ATTGTGCAAGAATATTTTTGATTGTCAAGTTCTATCTATCTAACATTGAATAAAGAAAAA
TGTCTAATAACGATGACGTTCAAAGATTTATCGGTCGTGGAAGTCGAAAAGGACATGGAA
TTGCTGTATTCACTAGTGGAGGTGACTCTCAGGGTATGAATGCTGCTGTACGTGCTGTTG
TTCGCATGGGAATTTACTTAGGATGCAAGGTAAATTTTGAATGGTTGATGGAGGTGAAAA
TATTGTAGAAGCAAATTGGGCATCTGTATCGAGTATCATTCATCGTGGAGGAACTGTTAT
TGGTTCAGCACGTTGTAAGGATTTTCGTGAACGTCCAGGACGTTTGAAGGCTGCTGAGAA
TCTCATTAAACGTGGAATCACAAATTTGGTCGTTATTGGCGGTGATGGTTCATTAACTGG
TGCTAATTTGTTCCGCGTTGAATGGAGTAGCTTATTAGACGAGTTACTGTCAACTGGAAG
AATTTCAACTGAAGAACGTCAAAAATATAAGAGCTTACATATCGCTGGTATGGTTGGATC
GATTGATAACGATTTTTGCGGTACTGACATGACAATTGGTACCGATTCTGCTTTACATCG
TATTATCGAGGCTATTGATGCTATTGTTAGTACTGCATATTCGCATCAGCGTACATTTAT
CATGGAAGTCATGGGAAGACA
>g10749.t3 Gene=g10749 Length=153
MVDGGENIVEANWASVSSIIHRGGTVIGSARCKDFRERPGRLKAAENLIKRGITNLVVIG
GDGSLTGANLFRVEWSSLLDELLSTGRISTEERQKYKSLHIAGMVGSIDNDFCGTDMTIG
TDSALHRIIEAIDAIVSTAYSHQRTFIMEVMGR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g10749.t3 | Gene3D | G3DSA:3.40.50.450 | - | 1 | 153 | 0 |
| 2 | g10749.t3 | PANTHER | PTHR13697 | PHOSPHOFRUCTOKINASE | 1 | 153 | 0 |
| 3 | g10749.t3 | PANTHER | PTHR13697:SF5 | ATP-DEPENDENT 6-PHOSPHOFRUCTOKINASE, PLATELET TYPE | 1 | 153 | 0 |
| 4 | g10749.t3 | PRINTS | PR00476 | ATP-dependent phosphofructokinase family signature | 52 | 68 | 0 |
| 7 | g10749.t3 | PRINTS | PR00476 | ATP-dependent phosphofructokinase family signature | 102 | 119 | 0 |
| 6 | g10749.t3 | PRINTS | PR00476 | ATP-dependent phosphofructokinase family signature | 120 | 138 | 0 |
| 5 | g10749.t3 | PRINTS | PR00476 | ATP-dependent phosphofructokinase family signature | 140 | 153 | 0 |
| 1 | g10749.t3 | Pfam | PF00365 | Phosphofructokinase | 7 | 153 | 0 |
| 8 | g10749.t3 | SUPERFAMILY | SSF53784 | Phosphofructokinase | 6 | 153 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0003872 | 6-phosphofructokinase activity | MF |
| GO:0006002 | fructose 6-phosphate metabolic process | BP |
| GO:0006096 | glycolytic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
