General information for g10800.t57
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Annexin B9.
Parent gene
- The parent gene g10800 is located on chr_1: 12053250..12057223 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10800 | g10800.t57 | isoform | g10800.t57 | 12051250 | 12057223 |
| chr_1 | g10800 | g10800.t57 | exon | g10800.t57.exon1 | 12051250 | 12052051 |
| chr_1 | g10800 | g10800.t57 | cds | g10800.t57.CDS1 | 12051998 | 12052051 |
| chr_1 | g10800 | g10800.t57 | exon | g10800.t57.exon2 | 12052686 | 12052867 |
| chr_1 | g10800 | g10800.t57 | cds | g10800.t57.CDS2 | 12052686 | 12052867 |
| chr_1 | g10800 | g10800.t57 | exon | g10800.t57.exon3 | 12052960 | 12053108 |
| chr_1 | g10800 | g10800.t57 | cds | g10800.t57.CDS3 | 12052960 | 12053108 |
| chr_1 | g10800 | g10800.t57 | exon | g10800.t57.exon4 | 12053171 | 12053303 |
| chr_1 | g10800 | g10800.t57 | cds | g10800.t57.CDS4 | 12053171 | 12053303 |
| chr_1 | g10800 | g10800.t57 | exon | g10800.t57.exon5 | 12053380 | 12053508 |
| chr_1 | g10800 | g10800.t57 | cds | g10800.t57.CDS5 | 12053380 | 12053508 |
| chr_1 | g10800 | g10800.t57 | exon | g10800.t57.exon6 | 12053572 | 12053869 |
| chr_1 | g10800 | g10800.t57 | cds | g10800.t57.CDS6 | 12053572 | 12053800 |
| chr_1 | g10800 | g10800.t57 | exon | g10800.t57.exon7 | 12055384 | 12055446 |
| chr_1 | g10800 | g10800.t57 | exon | g10800.t57.exon8 | 12057132 | 12057223 |
| chr_1 | g10800 | g10800.t57 | TSS | g10800.t57 | 12057215 | 12057215 |
| chr_1 | g10800 | g10800.t57 | TTS | g10800.t57 | NA | NA |
Sequences
>g10800.t57 Gene=g10800 Length=1848
ATTCTCTCAGTTTCAATTTGAACTTCGAGTGAGTAAGATTAAAAACGTAAGTGATCACTT
TCAAGTGTAATAAAAGTTAAATTTATCTTAAAAGTCGTATTAATTGTAAAGAGCAGCGAA
AATGAGTTCAGCAGCCTACTATCCATTCCAAGTAATGCAAACCAACCGTTTACCCTGCCG
ATCCTTTTGACCCAAATGAAGATGCAGGTATCTTGAGAAAGGCAATGAAAGGATTTGGAA
CTGATGAAAAGGCAATTATTGAAGTGCTTGCTCGTCGTGGAATTGTTCAACGTCTTGAGA
TTGCTTCGGCATATAAGACCAACTTTGGCAAGGATTTGATTAATGATTTGAAAAGTGAAC
TTGGTGGCAAGTTTGAAGATGTCATTCTTGCTTTGATGACTCCTTTGCCGCAATTCTATG
CAAAGGAATTGCATGATGCAATTTCCGGCATTGGAACTGACGAAGACGCTATCATCGAAA
TTCTCTGCACACTCTCCAACTATGGCATTCGTACAATTGCAGAATTCTACGAACAACTGT
ATGGAAATTCACTCGAAAGCGACTTGAAGGGAGACACCTCAGGATTCTTTAAGCGTTTAT
GCGTATCATTAGTGCAAGGCAATCGCGATGAAAACAATGGTGTTGATCAAGGTTCTGCTC
TTGCTGATGCTACTGCACTTTATGAAGCCGGTGAAGGACAATGGGGCACTGATGAGTCAG
TTTTCAATCAAATTCTTGTAACCAGATCATACCAACAATTGAGACAAGTCTTTTTGGAAT
ATGAGGCTATGAGCGGCCACGACATTGAAAAAGCTATCAAGCGTGAATTCTCAGGAAACG
CTGAAAAAGGATTCCTCGCAATCGCCAAGGTTGTCAAATCAAAGGTTGATTTCTTTGCTG
AAAAACTCTACGAGAGCATGAAGGGCTTAGGTACGAATGACAAGACATTGATTCGTATCA
TTGTTTCACGCTCAGAAATTGATTTGGGTGACATCAAAGAAGCATTTGAAGCCAAGTATG
GAAAAAGCCTCGAGAGCTGGGTTAAGGGTGACACCTCAGGCGATTATAAAAAATGTTTGT
TAGCACTTATTGGCGAGTAGAAGCTCATCGCATGAACATTTAAAATCCGATATATGAAAA
TAATTAGTTATTAAGAGATAACACACATACACAATATTATTGGACAAAAAATGTTTCTAC
ATTTACACACTATGAACATCATGTACTAAAATAATTTGTTTAAAAAAACTTCCATCAGTA
ATGTTCATTCACAATTTGCTTTTATTATTCGTTGGAAATTTGCAAAACTGTAGCTGTTAA
AATTCACATAAAATATTTTTTTAAAGTTGTTATATTCTTTGCAAGAAAAAAACTACATTT
TAGGAAAGAACTACATTTAAAAAAGCATTCAAATAAAATGATCGAAATAAAAAAGAGTAA
AAACTAAACTGACAACTTTTTTTATAAATTTATTCCGATTTCTCGAAAAAAAAATCAGAG
AGATGTGAGAAAACATCAAGAAAGTTTACCGCAGTTTCCTTTCGAGCAAATGGAGCAAAA
AAAATTGTGCTTTCAGAGAGGAACACAAATTTCATTTCGTCGATAAGCGCTCTTTTGAAA
TGACTTTCCGTTATGTTTCTGTTGCAAATGATGTCTCATCAACATAATTTTTTGTTCTTT
TTTCTTCTACTTACTTTCTAATTTTTTTCTTCTAAATTTATCATTAACTGTACATACGCT
TGACAATTGACAGCAGTCATATGCACTGTATAATTAGAGATCTATCACTAACAAATATAA
TATTTTATTCATATATTAACCAAAAGTAGTAATGATTCAAAAGCTTTC
>g10800.t57 Gene=g10800 Length=291
MKGFGTDEKAIIEVLARRGIVQRLEIASAYKTNFGKDLINDLKSELGGKFEDVILALMTP
LPQFYAKELHDAISGIGTDEDAIIEILCTLSNYGIRTIAEFYEQLYGNSLESDLKGDTSG
FFKRLCVSLVQGNRDENNGVDQGSALADATALYEAGEGQWGTDESVFNQILVTRSYQQLR
QVFLEYEAMSGHDIEKAIKREFSGNAEKGFLAIAKVVKSKVDFFAEKLYESMKGLGTNDK
TLIRIIVSRSEIDLGDIKEAFEAKYGKSLESWVKGDTSGDYKKCLLALIGE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 14 | g10800.t57 | Gene3D | G3DSA:1.10.220.10 | - | 1 | 59 | 2.1E-21 |
| 16 | g10800.t57 | Gene3D | G3DSA:1.10.220.10 | - | 61 | 132 | 5.7E-26 |
| 15 | g10800.t57 | Gene3D | G3DSA:1.10.220.10 | - | 133 | 219 | 2.3E-30 |
| 17 | g10800.t57 | Gene3D | G3DSA:1.10.220.10 | - | 221 | 291 | 3.2E-29 |
| 5 | g10800.t57 | PANTHER | PTHR10502 | ANNEXIN | 1 | 289 | 8.4E-134 |
| 6 | g10800.t57 | PANTHER | PTHR10502:SF212 | ANNEXIN B9 | 1 | 289 | 8.4E-134 |
| 11 | g10800.t57 | PRINTS | PR00196 | Annexin family signature | 2 | 24 | 1.8E-58 |
| 10 | g10800.t57 | PRINTS | PR00196 | Annexin family signature | 42 | 58 | 1.8E-58 |
| 12 | g10800.t57 | PRINTS | PR00196 | Annexin family signature | 69 | 90 | 1.8E-58 |
| 8 | g10800.t57 | PRINTS | PR00196 | Annexin family signature | 152 | 178 | 1.8E-58 |
| 9 | g10800.t57 | PRINTS | PR00196 | Annexin family signature | 232 | 252 | 1.8E-58 |
| 7 | g10800.t57 | PRINTS | PR00196 | Annexin family signature | 276 | 289 | 1.8E-58 |
| 4 | g10800.t57 | Pfam | PF00191 | Annexin | 1 | 57 | 2.0E-18 |
| 1 | g10800.t57 | Pfam | PF00191 | Annexin | 65 | 129 | 2.0E-22 |
| 3 | g10800.t57 | Pfam | PF00191 | Annexin | 148 | 213 | 1.4E-23 |
| 2 | g10800.t57 | Pfam | PF00191 | Annexin | 223 | 288 | 1.8E-25 |
| 18 | g10800.t57 | ProSitePatterns | PS00223 | Annexin repeat signature. | 5 | 57 | - |
| 19 | g10800.t57 | ProSitePatterns | PS00223 | Annexin repeat signature. | 236 | 288 | - |
| 25 | g10800.t57 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 1 | 59 | 23.568 |
| 24 | g10800.t57 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 60 | 131 | 27.041 |
| 27 | g10800.t57 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 143 | 215 | 27.356 |
| 26 | g10800.t57 | ProSiteProfiles | PS51897 | Annexin repeat profile. | 219 | 290 | 29.939 |
| 20 | g10800.t57 | SMART | SM00335 | annex3 | 5 | 57 | 4.1E-22 |
| 22 | g10800.t57 | SMART | SM00335 | annex3 | 77 | 129 | 3.3E-21 |
| 21 | g10800.t57 | SMART | SM00335 | annex3 | 161 | 213 | 5.4E-20 |
| 23 | g10800.t57 | SMART | SM00335 | annex3 | 236 | 288 | 8.2E-26 |
| 13 | g10800.t57 | SUPERFAMILY | SSF47874 | Annexin | 1 | 290 | 1.96E-114 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005544 | calcium-dependent phospholipid binding | MF |
| GO:0005509 | calcium ion binding | MF |
KEGG
Orthology
- This transcript has been annotated with K17095 (annexin A7/11)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
