Gene loci information

Transcript annotation

  • This transcript has been annotated as Kynurenine–oxoglutarate transaminase 3.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g10842 g10842.t6 TTS g10842.t6 12218402 12218402
chr_1 g10842 g10842.t6 isoform g10842.t6 12219351 12220534
chr_1 g10842 g10842.t6 exon g10842.t6.exon1 12219351 12219960
chr_1 g10842 g10842.t6 cds g10842.t6.CDS1 12219351 12219960
chr_1 g10842 g10842.t6 exon g10842.t6.exon2 12220023 12220461
chr_1 g10842 g10842.t6 cds g10842.t6.CDS2 12220023 12220177
chr_1 g10842 g10842.t6 exon g10842.t6.exon3 12220531 12220534
chr_1 g10842 g10842.t6 TSS g10842.t6 12220588 12220588

Sequences

>g10842.t6 Gene=g10842 Length=1053
ACAGTTTGATTTTGTACTTTCATTTGATCGCATTCGTAAGTAATAAAGAGAAATATGAAC
AGTTTACTATCTCTCCTGCTGTTGTAAGTCTTCACTGTACTATCATTTTTATTATCATTT
GTTTAATTCAATACATTCAAAAAAAAATTGAAAAATTCCTTATAATATTTCTATTTCTTT
AATTGAAGCCGTTATTGCTTTATTACTTCTCTATCGTAAGATCTCTCTACTATTGTAAAA
ATATTAGACAAACTGCTTATCTCAACACAAAATACATTTTTATTTTAGATGTTGATTAAA
TCTGCTTTTAATCAATTAAGAATTTGTCAACATATTTCTAGATCGTGCTTTATTAGTCCT
CATCGATTCATGGCATCCACTACTGCTGGCAGTGAAAAATTTGGTCTTCCTAAAAGATAT
CAGGAAGCATCAGAAAGTGTTTGGGTCGAATATGTAGCACTTGCGCTCAAATATAAACCA
CTAAACTTAGGTCAGGGTTTTCCAGATTATCCACCACCATCTTATGTCACAAAGGCATTA
TCAGATGTGGCGAATGGAGATCATTTGCTTAATCAATATACTAGGGGCTTTGGTCATCCT
CGACTAGTTAATGCTCTTGCAAAAGTTTATGGTCAATTGATTAATCGAGAAATTGATCCA
TTCAATGAAATACTTGTAACCGTTGGTGCTTATCAATCACTTTACAATGCAATTTACGGT
CATGTTGATCATGGCGATGAAGTCATTATTATCGAACCATTTTACGACTGTTATTATGAT
ATGATTAAATCAGCAGGAGGTATTGTAAAAGCAATCGCATTGAAACCGACAAAGACTGGT
GTAATCAGCTCAGCTGATTGGAAACTTGATCCCAAAGAATTAGAGTCACTCTTCAATGAG
AAAACTAAAATGATCATTTTAAACACACCGCACAATCCTCTTGGAAAAGTTTTTAATATA
GAAGAACTGACATTGATTGCTGATTTATGCAAAAAATGGAATGTAATGGTTGTAGCAGAT
GAAGTTTATGAGCATATGGTGTTTGAGCCAAAT

>g10842.t6 Gene=g10842 Length=255
MLIKSAFNQLRICQHISRSCFISPHRFMASTTAGSEKFGLPKRYQEASESVWVEYVALAL
KYKPLNLGQGFPDYPPPSYVTKALSDVANGDHLLNQYTRGFGHPRLVNALAKVYGQLINR
EIDPFNEILVTVGAYQSLYNAIYGHVDHGDEVIIIEPFYDCYYDMIKSAGGIVKAIALKP
TKTGVISSADWKLDPKELESLFNEKTKMIILNTPHNPLGKVFNIEELTLIADLCKKWNVM
VVADEVYEHMVFEPN

Protein features from InterProScan

Transcript Database ID Name Start End E.value
7 g10842.t6 CDD cd00609 AAT_like 65 254 0
5 g10842.t6 Gene3D G3DSA:3.90.1150.10 Aspartate Aminotransferase 28 104 0
6 g10842.t6 Gene3D G3DSA:3.40.640.10 - 105 255 0
2 g10842.t6 PANTHER PTHR43807:SF6 KYNURENINE–OXOGLUTARATE TRANSAMINASE 3 27 253 0
3 g10842.t6 PANTHER PTHR43807 FI04487P 27 253 0
1 g10842.t6 Pfam PF00155 Aminotransferase class I and II 64 253 0
4 g10842.t6 SUPERFAMILY SSF53383 PLP-dependent transferases 40 254 0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0009058 biosynthetic process BP
GO:0036137 kynurenine aminotransferase activity MF
GO:0006520 cellular amino acid metabolic process BP
GO:0070189 kynurenine metabolic process BP
GO:0003824 catalytic activity MF
GO:0030170 pyridoxal phosphate binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values