General information for g10859.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Serine protease inhibitor 77Ba.
Parent gene
- The parent gene g10859 is located on chr_1: 12310610..12311791 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10859 | g10859.t1 | TSS | g10859.t1 | 12308024 | 12308024 |
| chr_1 | g10859 | g10859.t1 | isoform | g10859.t1 | 12308424 | 12310610 |
| chr_1 | g10859 | g10859.t1 | exon | g10859.t1.exon1 | 12308424 | 12308430 |
| chr_1 | g10859 | g10859.t1 | cds | g10859.t1.CDS1 | 12308424 | 12308430 |
| chr_1 | g10859 | g10859.t1 | exon | g10859.t1.exon2 | 12308603 | 12309425 |
| chr_1 | g10859 | g10859.t1 | cds | g10859.t1.CDS2 | 12308603 | 12309425 |
| chr_1 | g10859 | g10859.t1 | exon | g10859.t1.exon3 | 12309488 | 12309716 |
| chr_1 | g10859 | g10859.t1 | cds | g10859.t1.CDS3 | 12309488 | 12309716 |
| chr_1 | g10859 | g10859.t1 | exon | g10859.t1.exon4 | 12309779 | 12310234 |
| chr_1 | g10859 | g10859.t1 | cds | g10859.t1.CDS4 | 12309779 | 12310234 |
| chr_1 | g10859 | g10859.t1 | exon | g10859.t1.exon5 | 12310285 | 12310452 |
| chr_1 | g10859 | g10859.t1 | cds | g10859.t1.CDS5 | 12310285 | 12310452 |
| chr_1 | g10859 | g10859.t1 | exon | g10859.t1.exon6 | 12310515 | 12310610 |
| chr_1 | g10859 | g10859.t1 | cds | g10859.t1.CDS6 | 12310515 | 12310610 |
| chr_1 | g10859 | g10859.t1 | TTS | g10859.t1 | 12310722 | 12310722 |
Sequences
>g10859.t1 Gene=g10859 Length=1779
ATGAATAAATTTTCTTCAACTTTATTTCTTTTACTGATTGCACTTATCTCGAGTGCAAAT
TCACAATCACGCGGAGAACTTTTAAATGCACCAATCCAACAAACAATTCGTCAAATTGAT
CCTTATACACAGCAAGTAAATAATCAAAAAGTTGCAGATAATTATAGGCCTCCTGTATAT
CAAACACAACAGAGACCACTTACACAGAATTATCAAACACAATCTTACAATCCACAATAC
ACTCAACAAACTCAACAACGTTATCCTATTCAAAATCAACAATATTCAAATCAACAACAA
TACTCAAATCAACCTCAAAGTTATCAAACACAACAGCAGCAGCAACAACAGTATAGACCT
GTTTATAACAATATTAGGCCACAACAGCAACAATCACAACAACAATTTTATAATAAACCT
CAACTTGATCAAAGAATTGATGGCATGCTTGGAGATGATGCTTCTGTAAATCGAGGAGGT
GTAAATGATAATGATTTTACGACTCGAAGACCATCAAGCACTGCTACTGGTCGAAAGACA
ACAAAAGCACCACTTTTTCCGCCTCGTTTTGATGATTATAATAGCCGAAAATTAACATGG
GATGAACAATTATCTCAGAATACTGAAGAATTTGCATTGAAATTATTTTTATACTTGACT
CATTTTGAGTCTGAAAATTTAATGATTTCTCCATACTCGATTCATTCACTTTTAGTAGTA
TTAGCTGAGGGTGCAGGTGGTAATACATATAATGAATTAAACAGTGCTCTCGGTTTAATC
AATAAACAACGAACAAGAGATTTCCATCAATATACGAATTTAGCTTTAAATAAAAGTGCG
TCAGATGTAAGCATTCGAAAATTTGCTGCTATGATAGGCGATAAAAATCGACCGATCGGA
CGCGAATATGAAGACAATGTAGAAAAGATTTATGATGTAGACTATATTCCTGTAAATTTC
CAAGAAGTAGAAAAAACATTACGTGAAGTAAATAACCGAGTTTCTCAAAGTACAAATGGA
CAAATAACTGACGCCATCTCACGTGATGACGTACTTAAAGCGCAATTAATACTGTTGGCA
GGTGTCCACTTTAAAGGAAATTGGAAAAATGTCTTCAATACCACTTTCACAAAGAATGAA
CCATTTTATGATATTCATCAGGAGAAAGAACTTGGAAGAGTTAATATGATGTTCCAAAGA
GGTCCATTTGCATATGCTGCTAATCAAAATCTTGGTTGTTATCTACTTGAATTACCCTAT
GGAGCTGACCGTGAATATGCAGAAAGAAATAATTTACCAGAAGGCACTGATGATCGAATT
TCAATGATTGTTGTGTTACCTAAGCGTGGTCTTTCGTTAGTTGATGCCATCGATAACGTT
AACAAATATGGAATAAAGAGCTTATTGTTTGAATTGAAAAAAGCTAAAGATGAATTTGAA
GATGAAGAAGTCGAAGTTCATCTTCCACGTTTTGAAATAGACACATCACTCAGTTTGAAG
GATACTTTACAAAGCATGGGTATAAATGATATTTTTGAGAATTCGGCAAACTTGTCAGGA
ATTAATAACAACTACTATGTGTCATCAATTCTTCACAAGACTAAAATTCGTGTGGATGAA
AAAGGAACTGAAGCATCGGCAGTGACAACTTCAATTTTTGCTAACAAAGCTACACCACCG
AAGTTCCATGCTAACAGACCCTTCTTTTACTTTATTGTTGATAAAGCTACGAGACTTATT
CTTTTTGCTGGTGTATATAGAAATCCTACACTTTTTTAA
>g10859.t1 Gene=g10859 Length=592
MNKFSSTLFLLLIALISSANSQSRGELLNAPIQQTIRQIDPYTQQVNNQKVADNYRPPVY
QTQQRPLTQNYQTQSYNPQYTQQTQQRYPIQNQQYSNQQQYSNQPQSYQTQQQQQQQYRP
VYNNIRPQQQQSQQQFYNKPQLDQRIDGMLGDDASVNRGGVNDNDFTTRRPSSTATGRKT
TKAPLFPPRFDDYNSRKLTWDEQLSQNTEEFALKLFLYLTHFESENLMISPYSIHSLLVV
LAEGAGGNTYNELNSALGLINKQRTRDFHQYTNLALNKSASDVSIRKFAAMIGDKNRPIG
REYEDNVEKIYDVDYIPVNFQEVEKTLREVNNRVSQSTNGQITDAISRDDVLKAQLILLA
GVHFKGNWKNVFNTTFTKNEPFYDIHQEKELGRVNMMFQRGPFAYAANQNLGCYLLELPY
GADREYAERNNLPEGTDDRISMIVVLPKRGLSLVDAIDNVNKYGIKSLLFELKKAKDEFE
DEEVEVHLPRFEIDTSLSLKDTLQSMGINDIFENSANLSGINNNYYVSSILHKTKIRVDE
KGTEASAVTTSIFANKATPPKFHANRPFFYFIVDKATRLILFAGVYRNPTLF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 15 | g10859.t1 | CDD | cd19598 | serpin77Ba-like_insects | 204 | 589 | 3.02164E-151 |
| 9 | g10859.t1 | Coils | Coil | Coil | 465 | 485 | - |
| 8 | g10859.t1 | Gene3D | G3DSA:3.30.497.10 | Antithrombin | 213 | 555 | 6.2E-94 |
| 7 | g10859.t1 | Gene3D | G3DSA:2.30.39.10 | - | 369 | 584 | 6.2E-94 |
| 20 | g10859.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 95 | 117 | - |
| 19 | g10859.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 155 | 181 | - |
| 21 | g10859.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 160 | 180 | - |
| 2 | g10859.t1 | PANTHER | PTHR11461:SF162 | SERINE PROTEASE INHIBITOR 77BA | 203 | 591 | 2.2E-97 |
| 3 | g10859.t1 | PANTHER | PTHR11461 | SERINE PROTEASE INHIBITOR, SERPIN | 203 | 591 | 2.2E-97 |
| 1 | g10859.t1 | Pfam | PF00079 | Serpin (serine protease inhibitor) | 207 | 589 | 4.1E-89 |
| 11 | g10859.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 21 | - |
| 12 | g10859.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 3 | - |
| 13 | g10859.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 4 | 16 | - |
| 14 | g10859.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 17 | 21 | - |
| 10 | g10859.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 22 | 592 | - |
| 18 | g10859.t1 | ProSitePatterns | PS00284 | Serpins signature. | 562 | 572 | - |
| 17 | g10859.t1 | SMART | SM00093 | serpin2 | 213 | 589 | 2.1E-66 |
| 4 | g10859.t1 | SUPERFAMILY | SSF56574 | Serpins | 194 | 589 | 1.07E-92 |
| 6 | g10859.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 21 | - |
| 16 | g10859.t1 | SignalP_GRAM_NEGATIVE | SignalP-noTM | SignalP-noTM | 1 | 21 | - |
| 5 | g10859.t1 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 25 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005615 | extracellular space | CC |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
