General information for g10859.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Serine protease inhibitor 77Ba.
Parent gene
- The parent gene g10859 is located on chr_1: 12310610..12311791 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10859 | g10859.t4 | isoform | g10859.t4 | 12309418 | 12310610 |
| chr_1 | g10859 | g10859.t4 | exon | g10859.t4.exon1 | 12309418 | 12309425 |
| chr_1 | g10859 | g10859.t4 | exon | g10859.t4.exon2 | 12309494 | 12309716 |
| chr_1 | g10859 | g10859.t4 | cds | g10859.t4.CDS1 | 12309528 | 12309716 |
| chr_1 | g10859 | g10859.t4 | exon | g10859.t4.exon3 | 12309779 | 12310234 |
| chr_1 | g10859 | g10859.t4 | cds | g10859.t4.CDS2 | 12309779 | 12310234 |
| chr_1 | g10859 | g10859.t4 | exon | g10859.t4.exon4 | 12310285 | 12310452 |
| chr_1 | g10859 | g10859.t4 | cds | g10859.t4.CDS3 | 12310285 | 12310452 |
| chr_1 | g10859 | g10859.t4 | exon | g10859.t4.exon5 | 12310515 | 12310610 |
| chr_1 | g10859 | g10859.t4 | cds | g10859.t4.CDS4 | 12310515 | 12310610 |
| chr_1 | g10859 | g10859.t4 | TTS | g10859.t4 | 12310722 | 12310722 |
| chr_1 | g10859 | g10859.t4 | TSS | g10859.t4 | NA | NA |
Sequences
>g10859.t4 Gene=g10859 Length=951
GCTTTAAATGCGTCAGATGTAAGCATTCGAAAATTTGCTGCTATGATAGGCGATAAAAAT
CGACCGATCGGACGCGAATATGAAGACAATGTAGAAAAGATTTATGATGTAGACTATATT
CCTGTAAATTTCCAAGAAGTAGAAAAAACATTACGTGAAGTAAATAACCGAGTTTCTCAA
AGTACAAATGGACAAATAACTGACGCCATCTCACGTGATGACGTACTTAAAGCGCAATTA
ATACTGTTGGCAGGTGTCCACTTTAAAGGAAATTGGAAAAATGTCTTCAATACCACTTTC
ACAAAGAATGAACCATTTTATGATATTCATCAGGAGAAAGAACTTGGAAGAGTTAATATG
ATGTTCCAAAGAGGTCCATTTGCATATGCTGCTAATCAAAATCTTGGTTGTTATCTACTT
GAATTACCCTATGGAGCTGACCGTGAATATGCAGAAAGAAATAATTTACCAGAAGGCACT
GATGATCGAATTTCAATGATTGTTGTGTTACCTAAGCGTGGTCTTTCGTTAGTTGATGCC
ATCGATAACGTTAACAAATATGGAATAAAGAGCTTATTGTTTGAATTGAAAAAAGCTAAA
GATGAATTTGAAGATGAAGAAGTCGAAGTTCATCTTCCACGTTTTGAAATAGACACATCA
CTCAGTTTGAAGGATACTTTACAAAGCATGGGTATAAATGATATTTTTGAGAATTCGGCA
AACTTGTCAGGAATTAATAACAACTACTATGTGTCATCAATTCTTCACAAGACTAAAATT
CGTGTGGATGAAAAAGGAACTGAAGCATCGGCAGTGACAACTTCAATTTTTGCTAACAAA
GCTACACCACCGAAGTTCCATGCTAACAGACCCTTCTTTTACTTTATTGTTGATAAAGCT
ACGAGACTTATTCTTTTTGCTGGTGTATATAGAAATCCTACACTTTTTTAA
>g10859.t4 Gene=g10859 Length=302
MIGDKNRPIGREYEDNVEKIYDVDYIPVNFQEVEKTLREVNNRVSQSTNGQITDAISRDD
VLKAQLILLAGVHFKGNWKNVFNTTFTKNEPFYDIHQEKELGRVNMMFQRGPFAYAANQN
LGCYLLELPYGADREYAERNNLPEGTDDRISMIVVLPKRGLSLVDAIDNVNKYGIKSLLF
ELKKAKDEFEDEEVEVHLPRFEIDTSLSLKDTLQSMGINDIFENSANLSGINNNYYVSSI
LHKTKIRVDEKGTEASAVTTSIFANKATPPKFHANRPFFYFIVDKATRLILFAGVYRNPT
LF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g10859.t4 | Coils | Coil | Coil | 175 | 195 | - |
| 10 | g10859.t4 | Gene3D | G3DSA:3.30.497.10 | Antithrombin | 3 | 252 | 4.6E-78 |
| 9 | g10859.t4 | Gene3D | G3DSA:2.30.39.10 | - | 81 | 299 | 4.6E-78 |
| 2 | g10859.t4 | PANTHER | PTHR11461:SF162 | SERINE PROTEASE INHIBITOR 77BA | 2 | 135 | 2.6E-82 |
| 4 | g10859.t4 | PANTHER | PTHR11461 | SERINE PROTEASE INHIBITOR, SERPIN | 2 | 135 | 2.6E-82 |
| 3 | g10859.t4 | PANTHER | PTHR11461:SF162 | SERINE PROTEASE INHIBITOR 77BA | 141 | 301 | 2.6E-82 |
| 5 | g10859.t4 | PANTHER | PTHR11461 | SERINE PROTEASE INHIBITOR, SERPIN | 141 | 301 | 2.6E-82 |
| 1 | g10859.t4 | Pfam | PF00079 | Serpin (serine protease inhibitor) | 3 | 299 | 3.5E-73 |
| 8 | g10859.t4 | ProSitePatterns | PS00284 | Serpins signature. | 272 | 282 | - |
| 7 | g10859.t4 | SMART | SM00093 | serpin2 | 1 | 299 | 3.6E-27 |
| 6 | g10859.t4 | SUPERFAMILY | SSF56574 | Serpins | 3 | 299 | 1.44E-75 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005615 | extracellular space | CC |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed