General information for g1088.t5
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Cytochrome P450 6a9.
Parent gene
- The parent gene g1088 is located on chr_3: 8073698..8075872 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1088 | g1088.t5 | TSS | g1088.t5 | 8073659 | 8073659 |
| chr_3 | g1088 | g1088.t5 | isoform | g1088.t5 | 8073698 | 8075872 |
| chr_3 | g1088 | g1088.t5 | exon | g1088.t5.exon1 | 8073698 | 8074616 |
| chr_3 | g1088 | g1088.t5 | cds | g1088.t5.CDS1 | 8073698 | 8074616 |
| chr_3 | g1088 | g1088.t5 | exon | g1088.t5.exon2 | 8074676 | 8074860 |
| chr_3 | g1088 | g1088.t5 | cds | g1088.t5.CDS2 | 8074676 | 8074860 |
| chr_3 | g1088 | g1088.t5 | exon | g1088.t5.exon3 | 8075416 | 8075636 |
| chr_3 | g1088 | g1088.t5 | cds | g1088.t5.CDS3 | 8075416 | 8075445 |
| chr_3 | g1088 | g1088.t5 | exon | g1088.t5.exon4 | 8075691 | 8075872 |
| chr_3 | g1088 | g1088.t5 | TTS | g1088.t5 | 8075893 | 8075893 |
Sequences
>g1088.t5 Gene=g1088 Length=1507
ATGATTTTAGAAATTTTACTTTCAATATTTTTCATTTTTTTACTTTCTCTCTATCGGCAT
TTTAAGAGAAATTATGAATTTTGGAGAAATAGACAGATTCCATTCTTGCAGCCAACATTT
CCAGTTGGTAATATGATGGAAGCTGTCAAAACAAAACAACATTTTGGTTTCGTCATGGAA
GATATTTACCAACACATGAAAAAACGATCAGATGTTGGTGACTATTGCGGCATTTTTTTC
TTTCATCAACCTGTGTTGCTCGTTATGACACCAGAATTTGCTAAAACAGTTTTAGTACGT
GATTTTAATTATTTTGCCGATCGTGGAGTTTATTCAAATGAGGAAGTTGATACATTAAGT
GGAAATTTATTCTTTCTTGAAGGACCAAGATGGAGGTTTTTAAGGCAAAAATTAGCTCCA
ACATTTACTTCAGGAAAACTTAAAAGTATGTTTCCAATAATTCTTGATGTTGGACAGAAA
TTTGTAGAACATTTAAAACCTTATGGAGAGAAGAACATGGAAATTGAAATTTATGATTTA
TTAGCAAGATTTTTAACTGATATTATCAGTTCTTGTGCTTTTGGTTTTGACTCAAATTCA
CTTGAAAATCCAGACAATGAATTTAGAACAATTTCGCAAAAAGGATTAAATTTAAGTAAA
TTCAAAAGCCTAAAATGTTTCCTCTCTATGGTTTTTAGAGAAAAAGCAAGAAAGTTTGGA
CTTCGATTCTTTGATGAAGAAATAAATGATTATTTTTCAAATTTGGTTGAAACAACAATC
GCAAATAGAAAGAAATCTGGCATTAAAAGAAAAGATTTCTTGGAACTTTTAATTAATTTG
ATGGAAAAAGATGATGAGAATGGTGAAAAATTGAATATAAAAGAAGTCACAGCTCAAGCA
TTTATTTTTATGATAGCAGGCTTTGAAACATCAAGCACAAATTTGTCCTATGCACTTCAT
CTTCTCGCTTATCATCAAGACATTCAAGATAAGGCTCGCAAAAGTATTGATAAAAAGCTT
AACGAATTTGACAATCAATGGAGTTACGATGCAATAATGGAAATGACGTATTTGGAGCAA
ATTATTGAAGAGTCTCTAAGGTCAAATTCACCCACCAATAGCAACATTACATAGAATTAC
AACCAAAGAATATACATTACCAAATGGAAAAACAATTCCTGAAAATACTGGAGTAATTAT
TCCAAATTTAGCTTATCAAAGAGATCCAGAACATTTTCCTGATCCTTTAAAATTTGATCC
TGAAAGATTCAATGCTGAAAATAAAAATTCAAGACATCAATTTACTTATTTACCTTTTGG
AGATGGACCACGTTTTTGTATTGGTATGAGATTTGGTCAACTTCAATCACGCCTTGGTCT
TGCACTTTTACTTAAAAATTTCAAATTCGAACCATGTGACAAAACTGAAAATCCAATAGA
AATTCATCCTATAAAGTTAATTTACGCTCCAAAAAATGGCATGTATTTGAGAATAAAGAA
AATTTAA
>g1088.t5 Gene=g1088 Length=377
MILEILLSIFFIFLLSLYRHFKRNYEFWRNRQIPFLQPTFPVGNMMEAVKTKQHFGFVME
DIYQHMKKRSDVGDYCGIFFFHQPVLLVMTPEFAKTVLVRDFNYFADRGVYSNEEVDTLS
GNLFFLEGPRWRFLRQKLAPTFTSGKLKSMFPIILDVGQKFVEHLKPYGEKNMEIEIYDL
LARFLTDIISSCAFGFDSNSLENPDNEFRTISQKGLNLSKFKSLKCFLSMVFREKARKFG
LRFFDEEINDYFSNLVETTIANRKKSGIKRKDFLELLINLMEKDDENGEKLNIKEVTAQA
FIFMIAGFETSSTNLSYALHLLAYHQDIQDKARKSIDKKLNEFDNQWSYDAIMEMTYLEQ
IIEESLRSNSPTNSNIT
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g1088.t5 | Gene3D | G3DSA:1.10.630.10 | Cytochrome p450 | 16 | 376 | 5.4E-85 |
| 2 | g1088.t5 | PANTHER | PTHR24292 | CYTOCHROME P450 | 5 | 372 | 4.0E-122 |
| 3 | g1088.t5 | PANTHER | PTHR24292:SF95 | CYP6A16, ISOFORM B-RELATED | 5 | 372 | 4.0E-122 |
| 5 | g1088.t5 | PRINTS | PR00464 | Group II E-class P450 signature | 128 | 148 | 2.4E-8 |
| 4 | g1088.t5 | PRINTS | PR00464 | Group II E-class P450 signature | 183 | 201 | 2.4E-8 |
| 1 | g1088.t5 | Pfam | PF00067 | Cytochrome P450 | 61 | 375 | 1.1E-57 |
| 9 | g1088.t5 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 19 | - |
| 10 | g1088.t5 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 4 | - |
| 11 | g1088.t5 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 5 | 15 | - |
| 12 | g1088.t5 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 16 | 19 | - |
| 8 | g1088.t5 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 20 | 377 | - |
| 6 | g1088.t5 | SUPERFAMILY | SSF48264 | Cytochrome P450 | 25 | 372 | 1.83E-68 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0020037 | heme binding | MF |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | MF |
| GO:0005506 | iron ion binding | MF |
| GO:0004497 | monooxygenase activity | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed