General information for g11019.t20
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as RAC serine/threonine-protein kinase.
Parent gene
- The parent gene g11019 is located on chr_1: 13430427..13431038 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11019 | g11019.t20 | isoform | g11019.t20 | 13429848 | 13430427 |
| chr_1 | g11019 | g11019.t20 | exon | g11019.t20.exon1 | 13429848 | 13430301 |
| chr_1 | g11019 | g11019.t20 | TSS | g11019.t20 | 13429880 | 13429880 |
| chr_1 | g11019 | g11019.t20 | cds | g11019.t20.CDS1 | 13429909 | 13430301 |
| chr_1 | g11019 | g11019.t20 | exon | g11019.t20.exon2 | 13430368 | 13430427 |
| chr_1 | g11019 | g11019.t20 | cds | g11019.t20.CDS2 | 13430368 | 13430427 |
| chr_1 | g11019 | g11019.t20 | TTS | g11019.t20 | 13430463 | 13430463 |
Sequences
>g11019.t20 Gene=g11019 Length=514
AGAAGTGCTTGAAGACAACGATTACGGACGTGCAGTCGATTGGTGGGGCACGGGTGTCGT
CATGTACGAAATGATTTGTGGTCGATTACCTTTTTACAATCGTGATCACGAAGTGCTTTT
TACTTTGATCATGGTCGAAGATGTGAAATTTCCACGTAACATTTCTAGTGAAGCGAGATC
ACTTTTAACTGGATTTCTTGAAAAAAGTCCCCAAAAGCGCCTCGGTGGTGGACCAGATGA
TGTTCGAGAAATAATGGTGCATCCTTTCTTTGCTAGCATCAATTGGTATGATTTAGTGAA
TAAGAAAATTATTCCACCGTTCAAGCCGCAAGTTACCTCAGATACTGATACACGCTATTT
CGATTCTGAATTTACGGGTGAGAGTGTCGAATTGACACCGCCTGATCCAGCTGTTCAATT
ACAATCAATTCAGGAAGAACCTCATTTTTCACAATTCAGCTATCAAGATTTAAATTCGTA
CATGAGCAGTTCTACACTTGCATCATTACAATAG
>g11019.t20 Gene=g11019 Length=150
MYEMICGRLPFYNRDHEVLFTLIMVEDVKFPRNISSEARSLLTGFLEKSPQKRLGGGPDD
VREIMVHPFFASINWYDLVNKKIIPPFKPQVTSDTDTRYFDSEFTGESVELTPPDPAVQL
QSIQEEPHFSQFSYQDLNSYMSSSTLASLQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g11019.t20 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 1 | 91 | 0.000 |
| 6 | g11019.t20 | Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 92 | 107 | 0.000 |
| 2 | g11019.t20 | PANTHER | PTHR24351:SF209 | NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE | 1 | 129 | 0.000 |
| 3 | g11019.t20 | PANTHER | PTHR24351 | RIBOSOMAL PROTEIN S6 KINASE | 1 | 129 | 0.000 |
| 1 | g11019.t20 | Pfam | PF00433 | Protein kinase C terminal domain | 91 | 134 | 0.000 |
| 9 | g11019.t20 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 1 | 70 | 8.924 |
| 8 | g11019.t20 | ProSiteProfiles | PS51285 | AGC-kinase C-terminal domain profile. | 71 | 144 | 15.824 |
| 5 | g11019.t20 | SMART | SM00133 | pkinase_C_6 | 71 | 136 | 0.000 |
| 4 | g11019.t20 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 1 | 137 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004674 | protein serine/threonine kinase activity | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
