Gene loci information

Transcript annotation

  • This transcript has been annotated as RAC serine/threonine-protein kinase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g11019 g11019.t9 TSS g11019.t9 13426353 13426353
chr_1 g11019 g11019.t9 isoform g11019.t9 13426358 13430427
chr_1 g11019 g11019.t9 exon g11019.t9.exon1 13426358 13426479
chr_1 g11019 g11019.t9 exon g11019.t9.exon2 13427342 13427912
chr_1 g11019 g11019.t9 cds g11019.t9.CDS1 13427539 13427912
chr_1 g11019 g11019.t9 exon g11019.t9.exon3 13428410 13428566
chr_1 g11019 g11019.t9 cds g11019.t9.CDS2 13428410 13428566
chr_1 g11019 g11019.t9 exon g11019.t9.exon4 13428631 13428828
chr_1 g11019 g11019.t9 cds g11019.t9.CDS3 13428631 13428828
chr_1 g11019 g11019.t9 exon g11019.t9.exon5 13428892 13428942
chr_1 g11019 g11019.t9 cds g11019.t9.CDS4 13428892 13428942
chr_1 g11019 g11019.t9 exon g11019.t9.exon6 13429013 13429113
chr_1 g11019 g11019.t9 cds g11019.t9.CDS5 13429013 13429113
chr_1 g11019 g11019.t9 exon g11019.t9.exon7 13429531 13429691
chr_1 g11019 g11019.t9 cds g11019.t9.CDS6 13429531 13429691
chr_1 g11019 g11019.t9 exon g11019.t9.exon8 13429848 13430301
chr_1 g11019 g11019.t9 cds g11019.t9.CDS7 13429848 13429921
chr_1 g11019 g11019.t9 exon g11019.t9.exon9 13430368 13430427
chr_1 g11019 g11019.t9 TTS g11019.t9 13430463 13430463

Sequences

>g11019.t9 Gene=g11019 Length=1875
GGAAAACAAAATTTAAAAGAACAAGTTGCATCAAAGCACTGCTATTAAATTCAAAAACAC
TCGAAAGATCATTAAATTGAGTGTCTGTAGTAAAGTTAAAACGTTAAAAAAATCGAAGAA
AAGAACTTTCCATCAAAACAATAATATTGTAATTAATTGTGTATAAAGAAGGAAATGTAA
AATAATTGTTGAAAGAAAAGAAACTTATTGATTAAAAAGAAATATATTCCACAGCATATT
GAGAAATTAATATTATTTGCATCATCATCAATAGTTTGTTTTGGGCAAATAAGAAGATAA
AAAAAAAAGTTGAGGAAAAATGTCACTTGCATCAACATCAATTGATTCAGGACAATTGCC
TGATCTTGTATCACATAATATTGACGTCAACTCGCGTCAAATCATTAAAGAAGGATGGTT
ATTTAAACGTGGTGAACATATAAAAAATTGGAGATCGCGCTATTTTATTTTACGATCAGA
CGGCTCACTTGTAGGCTATAAGAATCGACCAGACGCTCAAATTCCAACTGAGCCGTCCAA
TAATTTTACTGTTGCACGATGTCAAATCATGTCAGTTGATCGACCAAGACCTTATACATT
TATAATCAGAGGCCTACAATGGACCACTGTCATCGAGCGAATGTTTTATGTCGAGACAGA
GCATGAGAGAACCCAATGGGTTGAAGCTATACGGAGTGTTGCAAATCGTCTGAGTGAAAT
TGATCAACAAAAACAGGCTCAAGCTAATGAAGACATTGAAATGGTACCGATTGCTGAAGA
TGCCTTACTTAATGAAAAATTCTCACTTCAAGGTACATCAACAGGAAAAGTTAGTGGAAG
AAAAAAAGTGACATTGGAAAATTTTGAATTTTTAAAAGTATTGGGAAAAGGCACTTTTGG
AAAAGTAATTTTATGTCGTGAAAAAATCACAGCAAAATTATATGCTATTAAAATTCTTAA
AAAAGAAGTTATTATTCAAAAAGATGAAGTAAAACACACAATGGCTGAAAATCGTGTACT
TCAAAGAACAAATCATCCCTTTTTAATTTCGCTTAAATATTCATTTCAAACAAATGAACG
TTTATGTTTTGTCATGGAGTATGTCAACGGCGGTGAATTGTTCTTTCATTTAAGCCGTGA
CAGAATATTTTCAGAGGAACGTACTCGATTTTACGGAGCTGAAATAATATCTGCCCTCGG
ATATTTGCATTCGCACAACATTATTTATCGTGACTTAAAATTAGAAAATCTCTTACTTGA
TAAAGATGGTCATATAAAAATTGCAGATTTTGGTTTATGTAAGGAAGATATTACATATGG
TAGAACAACGAAAACTTTTTGTGGTGAGTTCAATATCACTGAGAAGTGCTTGAAGACAAC
GATTACGGACGTGCAGTCGATTGGTGGGGCACGGGTGTCGTCATGTACGAAATGATTTGT
GGTCGATTACCTTTTTACAATCGTGATCACGAAGTGCTTTTTACTTTGATCATGGTCGAA
GATGTGAAATTTCCACGTAACATTTCTAGTGAAGCGAGATCACTTTTAACTGGATTTCTT
GAAAAAAGTCCCCAAAAGCGCCTCGGTGGTGGACCAGATGATGTTCGAGAAATAATGGTG
CATCCTTTCTTTGCTAGCATCAATTGGTATGATTTAGTGAATAAGAAAATTATTCCACCG
TTCAAGCCGCAAGTTACCTCAGATACTGATACACGCTATTTCGATTCTGAATTTACGGGT
GAGAGTGTCGAATTGACACCGCCTGATCCAGCTGTTCAATTACAATCAATTCAGGAAGAA
CCTCATTTTTCACAATTCAGCTATCAAGATTTAAATTCGTACATGAGCAGTTCTACACTT
GCATCATTACAATAG

>g11019.t9 Gene=g11019 Length=371
MSLASTSIDSGQLPDLVSHNIDVNSRQIIKEGWLFKRGEHIKNWRSRYFILRSDGSLVGY
KNRPDAQIPTEPSNNFTVARCQIMSVDRPRPYTFIIRGLQWTTVIERMFYVETEHERTQW
VEAIRSVANRLSEIDQQKQAQANEDIEMVPIAEDALLNEKFSLQGTSTGKVSGRKKVTLE
NFEFLKVLGKGTFGKVILCREKITAKLYAIKILKKEVIIQKDEVKHTMAENRVLQRTNHP
FLISLKYSFQTNERLCFVMEYVNGGELFFHLSRDRIFSEERTRFYGAEIISALGYLHSHN
IIYRDLKLENLLLDKDGHIKIADFGLCKEDITYGRTTKTFCGEFNITEKCLKTTITDVQS
IGGARVSSCTK

Protein features from InterProScan

Transcript Database ID Name Start End E.value
10 g11019.t9 CDD cd01241 PH_PKB 26 131 1.88306E-62
8 g11019.t9 Gene3D G3DSA:2.30.29.30 - 22 143 1.4E-32
7 g11019.t9 Gene3D G3DSA:3.30.200.20 Phosphorylase Kinase; domain 1 176 268 9.6E-39
9 g11019.t9 Gene3D G3DSA:1.10.510.10 Transferase(Phosphotransferase) domain 1 269 347 1.6E-26
3 g11019.t9 PANTHER PTHR24351:SF209 NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE 29 343 1.5E-156
4 g11019.t9 PANTHER PTHR24351 RIBOSOMAL PROTEIN S6 KINASE 29 343 1.5E-156
1 g11019.t9 Pfam PF00169 PH domain 29 127 6.0E-16
2 g11019.t9 Pfam PF00069 Protein kinase domain 182 342 2.5E-47
12 g11019.t9 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 188 211 -
11 g11019.t9 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 301 313 -
16 g11019.t9 ProSiteProfiles PS50003 PH domain profile. 27 129 17.002
15 g11019.t9 ProSiteProfiles PS50011 Protein kinase domain profile. 182 371 32.527
13 g11019.t9 SMART SM00233 PH_update 28 131 5.5E-16
14 g11019.t9 SMART SM00220 serkin_6 182 370 8.6E-36
5 g11019.t9 SUPERFAMILY SSF50729 PH domain-like 24 134 6.43E-24
6 g11019.t9 SUPERFAMILY SSF56112 Protein kinase-like (PK-like) 173 342 3.51E-57

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005524 ATP binding MF
GO:0004672 protein kinase activity MF
GO:0006468 protein phosphorylation BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed