General information for g11097.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Formin-binding protein 1-like.
Parent gene
- The parent gene g11097 is located on chr_1: 14033940..14035243 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11097 | g11097.t1 | TSS | g11097.t1 | 14005897 | 14005897 |
| chr_1 | g11097 | g11097.t1 | isoform | g11097.t1 | 14006171 | 14034053 |
| chr_1 | g11097 | g11097.t1 | exon | g11097.t1.exon1 | 14006171 | 14006209 |
| chr_1 | g11097 | g11097.t1 | cds | g11097.t1.CDS1 | 14006171 | 14006209 |
| chr_1 | g11097 | g11097.t1 | exon | g11097.t1.exon2 | 14027347 | 14027462 |
| chr_1 | g11097 | g11097.t1 | cds | g11097.t1.CDS2 | 14027347 | 14027462 |
| chr_1 | g11097 | g11097.t1 | exon | g11097.t1.exon3 | 14029483 | 14029539 |
| chr_1 | g11097 | g11097.t1 | cds | g11097.t1.CDS3 | 14029483 | 14029539 |
| chr_1 | g11097 | g11097.t1 | exon | g11097.t1.exon4 | 14029681 | 14030295 |
| chr_1 | g11097 | g11097.t1 | cds | g11097.t1.CDS4 | 14029681 | 14030295 |
| chr_1 | g11097 | g11097.t1 | exon | g11097.t1.exon5 | 14030358 | 14030544 |
| chr_1 | g11097 | g11097.t1 | cds | g11097.t1.CDS5 | 14030358 | 14030544 |
| chr_1 | g11097 | g11097.t1 | exon | g11097.t1.exon6 | 14032213 | 14032577 |
| chr_1 | g11097 | g11097.t1 | cds | g11097.t1.CDS6 | 14032213 | 14032577 |
| chr_1 | g11097 | g11097.t1 | exon | g11097.t1.exon7 | 14032809 | 14032955 |
| chr_1 | g11097 | g11097.t1 | cds | g11097.t1.CDS7 | 14032809 | 14032955 |
| chr_1 | g11097 | g11097.t1 | exon | g11097.t1.exon8 | 14033670 | 14033833 |
| chr_1 | g11097 | g11097.t1 | cds | g11097.t1.CDS8 | 14033670 | 14033833 |
| chr_1 | g11097 | g11097.t1 | exon | g11097.t1.exon9 | 14033902 | 14034053 |
| chr_1 | g11097 | g11097.t1 | cds | g11097.t1.CDS9 | 14033902 | 14034053 |
| chr_1 | g11097 | g11097.t1 | TTS | g11097.t1 | NA | NA |
Sequences
>g11097.t1 Gene=g11097 Length=1842
ATGGGAACAATTACTAATTCTTGGGGAATTGAACTATGGGATCAATTTGGGAATATAGCA
GCACACACATTAAAGGGAATCGAATTTCTTGACAAGTATGGAAACTTTGTGAAAGATCGC
TGTGCCATTGAATTCGAATATGCATCAAAATTGAGACGACTCGCAAAGAATTATCAACCA
AAAGGAAAGAAAGGAGATGACGAAGATAATGAATTCACATCACATCAAGCATTCAAAAGT
GTGCTCAAAGAAACAAATGATTTAGCTGGGCAGCGAGAAGTTGTAGCAGAAAATCTTCAA
TCGCAAGTCATTGCTGGTATTAATCTACTTTCAAAAACGCTGCGTGAAGAAAGAAAAAAG
AGTCTTCAAGAAGGCACAGATCTCCAACAGAATTTAACAGCTCAATTGGCTGCACTCGAT
CGAGCAAAAAAGAATTATGAAAAGGCTTATCGTGAGGCGGAAAAGGCAGTAGAAAATTAT
CAAAAAGCAGACGCAGATTTTAATCTTAGTCGAGCGGAAGTAGAAAAACAGCGACATAAT
ATGACATTTAAATGTGCTCAATCAGATGATGCCAAAAATGAATATGCCAATCAATTACAG
AAGTCAAATAAACTTCAATATTCACATTTTCACACATCATTACCTGCGGTATTTAATAAA
TTACAAGAATTAGACGAGAAACGGACGCAAGGACTAAAAGAGTTCATTAAACAAGCGGCT
GAAGTTGAATCACAAGTCGCACCAATTATTGCACGATGCCTTGAAGGTATAGTGCGAGCA
TCAGAATCAATAAAAGAAAAGGAAGATTCAATAAAAGTGATAGAAAGATATCAATCAGGG
TTTCAACCACCAAACGATATTCCGTTTGAAGATCTTTCCAAAGCAGATAACGAGTCATCA
CACAATTCACAAATTAATTATGCCATGAATAATAATGCAACGATGAAAGGAACAATCGGT
GGTAAAGGACTTAAAAAGCGTGTAGGAATATTCAACATTTTTAGTAGCAATAAAAATACG
ATAACTGCTGATGGAATGAAGGATGATTTCAGTGATTTACCACCATCACAACGAAGAAAA
AAATTAATATCAAGAATTCAAGAAATTCAACAGAAAATTCAGCAAGAGCAAGGTGCAAGA
GATGGCCTGATAAAAATGAAAGGCGTTTATGAAAGCAATGCACTACTTGGTGATCCACAA
ACAGTTCAGGGAGAATTAAAAGAATGCGAACATAAACTTGAAAAACTCAAAAATGAACTG
AGAAAATATCAAATTTTATTGGAAGAAGTGAAAAGTCAAACTGCAAGTCAACATAGTCCA
CAAACAAATAGAAATACACATCATCAAAATGGAAGTCATGGAAATCACAGAATGTCACGA
CATTCCAATGGTAGCAATGAGGATGGTGGTGACGATGCGGTTGATGATGCCCGCAGTTTG
AGCAGGTCAGCATCAGAGAATAATGTCAATCAGCAAAATGGTGCACAAAATGGGCTAAAT
AATAACAATGAAAATAACAATAACGGCAGTAGTTCGGCAAGTCCCGAGTCAGGACTTGGC
ACATCACACTCATCATTACCGGGCTCTGGTCAAGGAAGTACGAATGATCATCATATAAAT
GATGATATGTATTATGATACAGATCCATTACCACCGCTTGGAACTTGTAAAGCATTATAT
CCATTTGATGGCAGTATTCCAATGGCAGAAGGAGAAGAACTTCATGTGATAGAACTTGAT
CAAGGAGATGGTTGGACGAGAGTACGAAGAATGGCTAATGGAAATTTGATGGAAGAAGGG
TTTGTTCCAACAAGTTATATTGAAAGCACTCTGTATGCGTAG
>g11097.t1 Gene=g11097 Length=613
MGTITNSWGIELWDQFGNIAAHTLKGIEFLDKYGNFVKDRCAIEFEYASKLRRLAKNYQP
KGKKGDDEDNEFTSHQAFKSVLKETNDLAGQREVVAENLQSQVIAGINLLSKTLREERKK
SLQEGTDLQQNLTAQLAALDRAKKNYEKAYREAEKAVENYQKADADFNLSRAEVEKQRHN
MTFKCAQSDDAKNEYANQLQKSNKLQYSHFHTSLPAVFNKLQELDEKRTQGLKEFIKQAA
EVESQVAPIIARCLEGIVRASESIKEKEDSIKVIERYQSGFQPPNDIPFEDLSKADNESS
HNSQINYAMNNNATMKGTIGGKGLKKRVGIFNIFSSNKNTITADGMKDDFSDLPPSQRRK
KLISRIQEIQQKIQQEQGARDGLIKMKGVYESNALLGDPQTVQGELKECEHKLEKLKNEL
RKYQILLEEVKSQTASQHSPQTNRNTHHQNGSHGNHRMSRHSNGSNEDGGDDAVDDARSL
SRSASENNVNQQNGAQNGLNNNNENNNNGSSSASPESGLGTSHSSLPGSGQGSTNDHHIN
DDMYYDTDPLPPLGTCKALYPFDGSIPMAEGEELHVIELDQGDGWTRVRRMANGNLMEEG
FVPTSYIESTLYA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g11097.t1 | CDD | cd07653 | F-BAR_CIP4-like | 10 | 262 | 3.25456E-113 |
| 12 | g11097.t1 | CDD | cd11619 | HR1_CIP4-like | 355 | 430 | 8.43569E-21 |
| 13 | g11097.t1 | CDD | cd11911 | SH3_CIP4-like | 555 | 608 | 4.88738E-24 |
| 9 | g11097.t1 | Coils | Coil | Coil | 129 | 166 | - |
| 8 | g11097.t1 | Coils | Coil | Coil | 359 | 379 | - |
| 10 | g11097.t1 | Coils | Coil | Coil | 406 | 433 | - |
| 7 | g11097.t1 | Gene3D | G3DSA:1.20.1270.60 | Arfaptin | 3 | 305 | 2.9E-74 |
| 6 | g11097.t1 | Gene3D | G3DSA:2.30.30.40 | SH3 Domains | 552 | 610 | 1.7E-9 |
| 17 | g11097.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 431 | 449 | - |
| 18 | g11097.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 431 | 473 | - |
| 20 | g11097.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 481 | 500 | - |
| 19 | g11097.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 507 | 533 | - |
| 2 | g11097.t1 | PANTHER | PTHR23065 | PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1 | 6 | 610 | 9.6E-168 |
| 3 | g11097.t1 | PANTHER | PTHR23065:SF47 | FORMIN-BINDING PROTEIN 1-LIKE PROTEIN | 6 | 610 | 9.6E-168 |
| 1 | g11097.t1 | Pfam | PF00611 | Fes/CIP4, and EFC/F-BAR homology domain | 15 | 93 | 1.2E-16 |
| 21 | g11097.t1 | ProSiteProfiles | PS51741 | F-BAR domain profile. | 6 | 269 | 36.103 |
| 22 | g11097.t1 | ProSiteProfiles | PS51860 | REM-1 domain profile. | 352 | 429 | 22.612 |
| 16 | g11097.t1 | SMART | SM00055 | fch_2 | 6 | 99 | 1.6E-13 |
| 15 | g11097.t1 | SMART | SM00742 | hr1_7 | 364 | 430 | 0.0029 |
| 14 | g11097.t1 | SMART | SM00326 | SH3_2 | 554 | 611 | 9.2E-7 |
| 4 | g11097.t1 | SUPERFAMILY | SSF103657 | BAR/IMD domain-like | 7 | 291 | 7.32E-74 |
| 5 | g11097.t1 | SUPERFAMILY | SSF50044 | SH3-domain | 549 | 608 | 1.3E-8 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0007165 | signal transduction | BP |
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K20121 (formin-binding protein 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
