General information for g11137.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Heat shock 70 kDa protein cognate 4.
Parent gene
- The parent gene g11137 is located on chr_1: 14304417..14305628 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11137 | g11137.t3 | isoform | g11137.t3 | 14302522 | 14303997 |
| chr_1 | g11137 | g11137.t3 | exon | g11137.t3.exon1 | 14302522 | 14302610 |
| chr_1 | g11137 | g11137.t3 | TTS | g11137.t3 | 14302528 | 14302528 |
| chr_1 | g11137 | g11137.t3 | cds | g11137.t3.CDS1 | 14302582 | 14302610 |
| chr_1 | g11137 | g11137.t3 | exon | g11137.t3.exon2 | 14302671 | 14303997 |
| chr_1 | g11137 | g11137.t3 | cds | g11137.t3.CDS2 | 14302671 | 14303658 |
| chr_1 | g11137 | g11137.t3 | TSS | g11137.t3 | NA | NA |
Sequences
>g11137.t3 Gene=g11137 Length=1416
GGCGGTGGTACATTTGATGTTTCAATTCTTTCAATTGATGATGGAATTTTTGAAGTAAAG
TCGACAGCCGGTGACACTCATCTTGGTGGTGAAGATTTTGATAATCGCCTCGTTAATCAT
TTTGCACAAGAGTTCAAACGTAAGCATAAAAAGGATTTGACTTCTAACAAGCGTGCACTT
CGACGTCTTAGAACAGCTTGTGAGCGTGCAAAGAGAACTTTGTCAAGCTCGACTCAAGCC
AGTATTGAAATTGATTCATTGTTCGAGGGTATTGATTTCTACACTTCAATTACTCGTGCA
CGTTTCGAAGAGTTGAATGCTGATCTCTTCCGTTCAACAATGGAGCCAGTTGAAAAAGCT
ATCCGTGATGCTAAAATGGACAAAGGAACAATTCATGATATCGTTCTTGTCGGTGGCTCA
ACTCGTATTCCAAAAGTTCAAAAATTACTTCAAGACTTCTTTAACGGCAAAGAGTTGAAC
AAATCAATTAATCCCGATGAGGCCGTCGCTTATGGTGCTGCTGTTCAAGCTGCCATTTTG
CACGGAGACAAGAGCGAAGAAGTTCAAGACTTGCTTCTTTTGGACGTTACTCCATTGTCA
CTCGGTATTGAAACAGCTGGTGGTGTCATGAGCGTTTTGATTAAACGTAATACAACAATT
CCAACCAAGCAAACTCAAACTTTCACCACCTATTCAGATAATCAACCAGGAGTATTGATT
CAAGTATTTGAAGGCGAACGTGCTATGACCAAGGATAACAATCTTCTCGGTAAATTCGAA
CTTGCCGGTATTCCTCCTGCTCCACGCGGTGTCCCACAAATTGAAGTTACATTTGATATC
GATGCAAACGGTATTTTGAATGTTACTGCTTTGGAAAAATCAACAAATAAGGAAAACAAG
ATCACAATTACAAACGACAAGGGACGTTTGAGCAAAGAAGATATCGAACGTATGGTTAAT
GAAGCTGAGAAATACCGTTCAGAGGATGATGCACAAAAAGATCGCATTGCAGCCAAGAAC
GGTTTGGAATCATACTGCTTCAACATGAAGGCTACAATGGAAGATGATAAATTGAAGGAT
AAGATCTCTGAAAGTGACAAGAAGACCATTTTGGACAAATGCAATGATACTATTAAATGG
CTCGATGCAAATCAATTGGGTGAAAAGGAAGAATATGAACACCGTCAAAAAGAATTAGAA
GGAATTTGCAATCCAATTATCACTAAATTATATCAATCTGCTGGTGGTGCTCCTGGTGGT
ATGCCTGGCTTCCCTGGAGCTGGTGCAGCTGGCGGTGGCGGCGCAGCAGGAGCTGGTGCA
GGATCAGCGATAAATAAAAGTTATAAGAGAGAGTGAAGAACTAATAAAAAACGCAACTTG
CAAAAGTTGTTAAACGAACAATGGAAGAATAATTTT
>g11137.t3 Gene=g11137 Length=338
MEPVEKAIRDAKMDKGTIHDIVLVGGSTRIPKVQKLLQDFFNGKELNKSINPDEAVAYGA
AVQAAILHGDKSEEVQDLLLLDVTPLSLGIETAGGVMSVLIKRNTTIPTKQTQTFTTYSD
NQPGVLIQVFEGERAMTKDNNLLGKFELAGIPPAPRGVPQIEVTFDIDANGILNVTALEK
STNKENKITITNDKGRLSKEDIERMVNEAEKYRSEDDAQKDRIAAKNGLESYCFNMKATM
EDDKLKDKISESDKKTILDKCNDTIKWLDANQLGEKEEYEHRQKELEGICNPIITKLYQS
AGGAPGGMPGFPGAGAAGGGGAAGAGAGSAINKSYKRE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g11137.t3 | Gene3D | G3DSA:3.30.420.40 | - | 1 | 52 | 1.5E-25 |
| 14 | g11137.t3 | Gene3D | G3DSA:3.30.420.40 | - | 53 | 65 | 1.5E-25 |
| 12 | g11137.t3 | Gene3D | G3DSA:2.60.34.10 | Substrate Binding Domain Of DNAk; Chain A | 67 | 196 | 1.5E-66 |
| 15 | g11137.t3 | Gene3D | G3DSA:1.20.1270.10 | - | 197 | 300 | 8.6E-40 |
| 2 | g11137.t3 | PANTHER | PTHR19375 | HEAT SHOCK PROTEIN 70KDA | 1 | 306 | 1.1E-177 |
| 3 | g11137.t3 | PANTHER | PTHR19375:SF382 | HEAT SHOCK-RELATED 70 KDA PROTEIN 2 | 1 | 306 | 1.1E-177 |
| 4 | g11137.t3 | PRINTS | PR00301 | 70kDa heat shock protein signature | 18 | 34 | 1.1E-46 |
| 5 | g11137.t3 | PRINTS | PR00301 | 70kDa heat shock protein signature | 50 | 70 | 1.1E-46 |
| 6 | g11137.t3 | PRINTS | PR00301 | 70kDa heat shock protein signature | 77 | 96 | 1.1E-46 |
| 7 | g11137.t3 | PRINTS | PR00301 | 70kDa heat shock protein signature | 158 | 174 | 1.1E-46 |
| 1 | g11137.t3 | Pfam | PF00012 | Hsp70 protein | 1 | 299 | 1.3E-106 |
| 11 | g11137.t3 | ProSitePatterns | PS01036 | Heat shock hsp70 proteins family signature 3. | 21 | 35 | - |
| 10 | g11137.t3 | SUPERFAMILY | SSF53067 | Actin-like ATPase domain | 2 | 69 | 4.98E-21 |
| 9 | g11137.t3 | SUPERFAMILY | SSF100920 | Heat shock protein 70kD (HSP70), peptide-binding domain | 73 | 230 | 9.42E-65 |
| 8 | g11137.t3 | SUPERFAMILY | SSF100934 | Heat shock protein 70kD (HSP70), C-terminal subdomain | 225 | 306 | 1.06E-32 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0016887 | ATP hydrolysis activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
