General information for g11141.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Uroporphyrinogen-III synthase.
Parent gene
- The parent gene g11141 is located on chr_1: 14317933..14318808 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11141 | g11141.t2 | TTS | g11141.t2 | 14317771 | 14317771 |
| chr_1 | g11141 | g11141.t2 | isoform | g11141.t2 | 14317933 | 14318808 |
| chr_1 | g11141 | g11141.t2 | exon | g11141.t2.exon1 | 14317933 | 14318696 |
| chr_1 | g11141 | g11141.t2 | cds | g11141.t2.CDS1 | 14317933 | 14318685 |
| chr_1 | g11141 | g11141.t2 | exon | g11141.t2.exon2 | 14318764 | 14318808 |
| chr_1 | g11141 | g11141.t2 | TSS | g11141.t2 | 14318785 | 14318785 |
Sequences
>g11141.t2 Gene=g11141 Length=809
CAATGATATTATCCAAATGGACAAGAAATATTCTTAAACGAAATTTTAATTCAAAAATGA
CAAAGATAATTTTATTTAAATCAGAAAGTGATGGTGGTGATAAATTTGTAGAAGAGCTTG
AAAAAAATAATTTTGTAGTGCAGTCAATTCCATCGATAGATTTTGAATTTAAAAATCTTG
ATATTTTATCAGAGAAATTAAGAAAATCAAATGATTATGAAGGTATAATTTTTACAAGTC
CTCGGTCAATTTTTGCCACGCAACAATTATTAAAGAGCAATCCTGATAATTTAAAATCTT
GGAGTGATAAGAGAAATTTCACTGTCGGTGAATCAACGTATAATTTAGCAAAAAAATTGA
TATCACTTGAGACAGCAGGAAAAGAAGCTGGAAATGCTCAAAATTTATCAACTATAATCA
TTAGTTGTTATAATAAAAATAAATTAACGAAACCATTCCTATTTCCTTGCGGTAATTTAA
AACAAGATATACTAGAAAAGAATCTCAACGAGAATTCAATCCTGCTTGACTGTATTGAAG
TATATGATACAATACCACATCCGAATTTGGAAAATGCAATACTCAAACTAAAAGAAGAAG
ATGACATCAATTTTATCGTTTATTTTAGTCCATCGGGAATAAAATATTCCATGCCATTCA
TTAAACATCACAATTTACCGCTTTCAAAATGTAAGTTAATTGCTATTGGACCATCAACAA
AACGATGTATGCGTGATTACAATCTCGAATGCTACGCAATGTGCGAAAAACCATCACCAG
AAAGTTTATTGAACGTTCTTAAGAAATAA
>g11141.t2 Gene=g11141 Length=250
MTKIILFKSESDGGDKFVEELEKNNFVVQSIPSIDFEFKNLDILSEKLRKSNDYEGIIFT
SPRSIFATQQLLKSNPDNLKSWSDKRNFTVGESTYNLAKKLISLETAGKEAGNAQNLSTI
IISCYNKNKLTKPFLFPCGNLKQDILEKNLNENSILLDCIEVYDTIPHPNLENAILKLKE
EDDINFIVYFSPSGIKYSMPFIKHHNLPLSKCKLIAIGPSTKRCMRDYNLECYAMCEKPS
PESLLNVLKK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g11141.t2 | CDD | cd06578 | HemD | 4 | 248 | 0 |
| 4 | g11141.t2 | Gene3D | G3DSA:3.40.50.10090 | - | 15 | 245 | 0 |
| 5 | g11141.t2 | Gene3D | G3DSA:3.40.50.10090 | - | 34 | 170 | 0 |
| 2 | g11141.t2 | PANTHER | PTHR12390 | UROPORPHYRINOGEN III SYNTHASE | 2 | 249 | 0 |
| 1 | g11141.t2 | Pfam | PF02602 | Uroporphyrinogen-III synthase HemD | 15 | 245 | 0 |
| 3 | g11141.t2 | SUPERFAMILY | SSF69618 | HemD-like | 3 | 249 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0033014 | tetrapyrrole biosynthetic process | BP |
| GO:0006780 | uroporphyrinogen III biosynthetic process | BP |
| GO:0004852 | uroporphyrinogen-III synthase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K01719 (uroporphyrinogen-III synthase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
