General information for g11155.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Aurora kinase A-A.
Parent gene
- The parent gene g11155 is located on chr_1: 14357770..14358513 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11155 | g11155.t3 | TTS | g11155.t3 | 14356843 | 14356843 |
| chr_1 | g11155 | g11155.t3 | isoform | g11155.t3 | 14357770 | 14358513 |
| chr_1 | g11155 | g11155.t3 | exon | g11155.t3.exon1 | 14357770 | 14357906 |
| chr_1 | g11155 | g11155.t3 | cds | g11155.t3.CDS1 | 14357770 | 14357906 |
| chr_1 | g11155 | g11155.t3 | exon | g11155.t3.exon2 | 14357979 | 14358513 |
| chr_1 | g11155 | g11155.t3 | cds | g11155.t3.CDS2 | 14357979 | 14358513 |
| chr_1 | g11155 | g11155.t3 | TSS | g11155.t3 | 14358623 | 14358623 |
Sequences
>g11155.t3 Gene=g11155 Length=672
ATGAATAGTCACGCAATTAAACAGAATGGAAAGGAAAACTGTTTATATAACGAGAAAAAG
AATAGACAAATTTATACTCATCAACAGCAACCAAAATCAGTTTTATCGTCATCAACTACA
ATTAACAATACTGTGAATGATAATGCAATTAAGAATCCTAATCTTCTCAATATAAAGCCT
ATCACGCAAAAACCTCAAATTTCATCTTCGAATGCTCCTGGATCTTCTTCCTCAAACAAT
CAACAGCAGCAGCACCAACAATCTAGAAAATCTTGGTCTTTAGTTAATTTTGATATAGGC
CGTCCTTTGGGTCGTGGAAAATTTGGAAATGTGTACTTGGCGAGAGAAAAGGAGACTAAA
TTTGTTATTGCCCTTAAGGTTCTTTTTAAGAAACAAGTCGCTGAGCAAGGAATTGAACAT
CAAGTTCGTCGAGAAATTGAAATTCAAAGTCATTTAAGACATCCAAATATTCTTCGTATG
TATGGATTCTTTCATGATGAAGCACGCATTTATTTGATTTTGGAATATGCTCCAGGAGGA
ACATTATTCAATGCATTGAAAAATCAACCTAACAATCGTTTTAACGAACAAAAGTCAGCA
AAGTATATTAAATGTTTAGTATCTGCACTCTCATATTTGCACGAAAAGAATGTGATTCAT
CGAGACATTAAG
>g11155.t3 Gene=g11155 Length=224
MNSHAIKQNGKENCLYNEKKNRQIYTHQQQPKSVLSSSTTINNTVNDNAIKNPNLLNIKP
ITQKPQISSSNAPGSSSSNNQQQQHQQSRKSWSLVNFDIGRPLGRGKFGNVYLAREKETK
FVIALKVLFKKQVAEQGIEHQVRREIEIQSHLRHPNILRMYGFFHDEARIYLILEYAPGG
TLFNALKNQPNNRFNEQKSAKYIKCLVSALSYLHEKNVIHRDIK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g11155.t3 | Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 84 | 177 | 9.3E-36 |
| 6 | g11155.t3 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 178 | 224 | 1.7E-11 |
| 9 | g11155.t3 | MobiDBLite | mobidb-lite | consensus disorder prediction | 65 | 91 | - |
| 2 | g11155.t3 | PANTHER | PTHR24350:SF0 | AURORA A | 21 | 224 | 2.1E-74 |
| 3 | g11155.t3 | PANTHER | PTHR24350 | SERINE/THREONINE-PROTEIN KINASE IAL-RELATED | 21 | 224 | 2.1E-74 |
| 1 | g11155.t3 | Pfam | PF00069 | Protein kinase domain | 99 | 224 | 2.6E-34 |
| 7 | g11155.t3 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 103 | 126 | - |
| 10 | g11155.t3 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 97 | 224 | 28.019 |
| 8 | g11155.t3 | SMART | SM00220 | serkin_6 | 97 | 224 | 2.6E-9 |
| 4 | g11155.t3 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 83 | 224 | 2.08E-41 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
