General information for g11174.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Transcriptional coactivator yorkie.
Parent gene
- The parent gene g11174 is located on chr_1: 14420837..14421693 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11174 | g11174.t1 | isoform | g11174.t1 | 14401258 | 14420837 |
| chr_1 | g11174 | g11174.t1 | exon | g11174.t1.exon1 | 14401258 | 14401302 |
| chr_1 | g11174 | g11174.t1 | cds | g11174.t1.CDS1 | 14401258 | 14401302 |
| chr_1 | g11174 | g11174.t1 | exon | g11174.t1.exon2 | 14401366 | 14401424 |
| chr_1 | g11174 | g11174.t1 | cds | g11174.t1.CDS2 | 14401366 | 14401424 |
| chr_1 | g11174 | g11174.t1 | exon | g11174.t1.exon3 | 14401492 | 14401621 |
| chr_1 | g11174 | g11174.t1 | cds | g11174.t1.CDS3 | 14401492 | 14401621 |
| chr_1 | g11174 | g11174.t1 | exon | g11174.t1.exon4 | 14401693 | 14401787 |
| chr_1 | g11174 | g11174.t1 | cds | g11174.t1.CDS4 | 14401693 | 14401787 |
| chr_1 | g11174 | g11174.t1 | exon | g11174.t1.exon5 | 14402021 | 14402194 |
| chr_1 | g11174 | g11174.t1 | cds | g11174.t1.CDS5 | 14402021 | 14402194 |
| chr_1 | g11174 | g11174.t1 | exon | g11174.t1.exon6 | 14403954 | 14404120 |
| chr_1 | g11174 | g11174.t1 | cds | g11174.t1.CDS6 | 14403954 | 14404120 |
| chr_1 | g11174 | g11174.t1 | exon | g11174.t1.exon7 | 14419993 | 14420837 |
| chr_1 | g11174 | g11174.t1 | cds | g11174.t1.CDS7 | 14419993 | 14420837 |
| chr_1 | g11174 | g11174.t1 | TSS | g11174.t1 | 14421693 | 14421693 |
| chr_1 | g11174 | g11174.t1 | TTS | g11174.t1 | NA | NA |
Sequences
>g11174.t1 Gene=g11174 Length=1515
ATGGCCTTTAACAATACAAGCAGTGGTGCTCAGTCACAACAAACAAATCAACTTCAGCAA
GGTGCTGCAGATGATGATGCACTACAACAGCAACAAAAAAAGAATAATAATCTCATAATA
TTGGTTGACAAGGATTCAAATGACAAGCTTGATGAGCTTTTTGAAAAGACGTTGAACAAT
ACTACGTCTCTTCATAAGCCTTATAAAATGCGCAAATTGCCAGCGTCATTCTTTAAGCCA
CCACAATCAGGCTCAAAATCGCCATCGGTTTCACATTCGCGCGAAAATTCTGCTGACTCT
GCATTTGGTTCAGGCACAACCATATTGAATAATGTTAATAATCAGAATAACAATAACAAT
AGTAATAATAGTGTAACTCCACATCCAGCTATAGCACCAGCAACAGCATCGGCCATAAAT
GGTCTCGCCATACACCACTCGCGTGCTCACAGTAGCCCCGCAAGCTTGGGCAAGTTGCCT
CTCAACATAAACCTCAATTTGAGTGCCTTAAATCTCGGAACAGTGACACCAACAAATAGT
CCTAGTCCGAATCATTCGACAACAAATATCAACAGCAGTAGCAACATGACTAACAATTCC
AATAAAGCAAATACAAACAATATCTTGAGTAGTAACGCTGTTGGTGGCGCAGGAGCGGTC
AATAATCAGACCAATACTAACAACAATTTACCACACAACATAAGCTTGGAAAAAACTTTG
CAACATATTCACAGTCGTGGACGCAGCTACGATATTCCAAGTTTGCAGCATCAATTGCAA
TTCAGTGAACTGCCACCAGGCTGGGAACAAGCAAAGACATCAGACGGAAAAGTTTATTAT
ATCAATCATAATGATCGTACAACACAATGGGAAGATCCAAGAACTCAAATGGCTGCTCAA
GCTCTATCACATGGAAATTTGTTCTCATCATCTTCATCAGAACACTCAAGTGTAGAAACA
CTTTTCAGCACGCCCACACAACTTAGCTCATTAGGATCATCGTCACAAAACGTTATCGAT
TCACAATCAATCATCACGCCGACAATTTTAGCCGGCAGTAATAACAGTACTAACTTGACG
CCATTAGAATGGCCTTGGGAAGAAGGTCTAACCGAGAATGGTGAGCGCTATTATATCAAC
CATGTCACTCGCACGACCAGTTGGAGAGATCCAAGATTAAAATTATCTAATCAAGAATGG
GAACAAAATCTCCGCATTTATAATTTGCAATTGGAACGTGAACGTTTGAAGACACGCAGA
CAGGAAATTGCTAAATTAAATATTGGAGAAGATCCATTTCTTCCGGGAATTACTGATCAT
ACACGACAAGAAAGTGGTGATAGTGGTCTTTCTTTATCTCACACACCCGATTTCTTATGC
GATGACAGTATGGATGGACTTAGTGTTAGTGTGACTGATTCAACAATGGAAGCTTTTAAT
GAAGCAATGGAGACACCAGATGAATTTATGCTAAATGATCCTCTTTTACTTGAGAAAATT
GGTGGTCTGATATGA
>g11174.t1 Gene=g11174 Length=504
MAFNNTSSGAQSQQTNQLQQGAADDDALQQQQKKNNNLIILVDKDSNDKLDELFEKTLNN
TTSLHKPYKMRKLPASFFKPPQSGSKSPSVSHSRENSADSAFGSGTTILNNVNNQNNNNN
SNNSVTPHPAIAPATASAINGLAIHHSRAHSSPASLGKLPLNINLNLSALNLGTVTPTNS
PSPNHSTTNINSSSNMTNNSNKANTNNILSSNAVGGAGAVNNQTNTNNNLPHNISLEKTL
QHIHSRGRSYDIPSLQHQLQFSELPPGWEQAKTSDGKVYYINHNDRTTQWEDPRTQMAAQ
ALSHGNLFSSSSSEHSSVETLFSTPTQLSSLGSSSQNVIDSQSIITPTILAGSNNSTNLT
PLEWPWEEGLTENGERYYINHVTRTTSWRDPRLKLSNQEWEQNLRIYNLQLERERLKTRR
QEIAKLNIGEDPFLPGITDHTRQESGDSGLSLSHTPDFLCDDSMDGLSVSVTDSTMEAFN
EAMETPDEFMLNDPLLLEKIGGLI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g11174.t1 | CDD | cd00201 | WW | 265 | 294 | 2.54856E-14 |
| 10 | g11174.t1 | CDD | cd00201 | WW | 365 | 393 | 3.74327E-9 |
| 8 | g11174.t1 | Coils | Coil | Coil | 397 | 417 | - |
| 6 | g11174.t1 | Gene3D | G3DSA:2.20.70.10 | - | 259 | 300 | 1.2E-19 |
| 7 | g11174.t1 | Gene3D | G3DSA:2.20.70.10 | - | 352 | 398 | 1.9E-13 |
| 16 | g11174.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 28 | - |
| 15 | g11174.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 74 | 99 | - |
| 14 | g11174.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 80 | 99 | - |
| 3 | g11174.t1 | PANTHER | PTHR17616 | YES-ASSOCIATED PROTEIN YAP1 FAMILY MEMBER | 10 | 460 | 7.9E-56 |
| 1 | g11174.t1 | Pfam | PF00397 | WW domain | 264 | 293 | 1.5E-13 |
| 2 | g11174.t1 | Pfam | PF00397 | WW domain | 363 | 391 | 1.9E-7 |
| 13 | g11174.t1 | ProSitePatterns | PS01159 | WW/rsp5/WWP domain signature. | 268 | 293 | - |
| 18 | g11174.t1 | ProSiteProfiles | PS50020 | WW/rsp5/WWP domain profile. | 262 | 295 | 18.461 |
| 17 | g11174.t1 | ProSiteProfiles | PS50020 | WW/rsp5/WWP domain profile. | 360 | 393 | 16.057 |
| 11 | g11174.t1 | SMART | SM00456 | ww_5 | 263 | 295 | 5.7E-14 |
| 12 | g11174.t1 | SMART | SM00456 | ww_5 | 361 | 393 | 1.2E-7 |
| 5 | g11174.t1 | SUPERFAMILY | SSF51045 | WW domain | 261 | 298 | 7.79E-15 |
| 4 | g11174.t1 | SUPERFAMILY | SSF51045 | WW domain | 358 | 393 | 3.26E-10 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K16687 (transcriptional coactivator YAP1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
