General information for g11190.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Serine/threonine-protein kinase PAK 3.
Parent gene
- The parent gene g11190 is located on chr_1: 14497518..14504469 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11190 | g11190.t4 | isoform | g11190.t4 | 14494643 | 14497627 |
| chr_1 | g11190 | g11190.t4 | exon | g11190.t4.exon1 | 14494643 | 14494820 |
| chr_1 | g11190 | g11190.t4 | cds | g11190.t4.CDS1 | 14494644 | 14494820 |
| chr_1 | g11190 | g11190.t4 | exon | g11190.t4.exon2 | 14497304 | 14497455 |
| chr_1 | g11190 | g11190.t4 | cds | g11190.t4.CDS2 | 14497304 | 14497455 |
| chr_1 | g11190 | g11190.t4 | exon | g11190.t4.exon3 | 14497516 | 14497627 |
| chr_1 | g11190 | g11190.t4 | cds | g11190.t4.CDS3 | 14497516 | 14497627 |
| chr_1 | g11190 | g11190.t4 | TSS | g11190.t4 | NA | NA |
| chr_1 | g11190 | g11190.t4 | TTS | g11190.t4 | NA | NA |
Sequences
>g11190.t4 Gene=g11190 Length=442
ATGTCAAGTGATGAAGATAAACCACCAGCACCGCCTATTAGATTGACAAGCAATCGAAGT
GGAAGTGATAGGCTTGATGGACCACCTCCTGATCTTAAACCACTACCTAAAGAACCCGAC
GATCCAGATCGCAAAAAGAAAACATTAAAAAATAAAATTAAATCGACAAAATCACACAAT
GACTCCAAACCGAATATTTCATATCCAACAAATTTCGAGCATACGGTTCACGTTGGCTTT
GATGCAATCACAGGAGAATTCACAGGAATGCCGGAGCAATGGGCAGTATTATTAATGAAC
AGCAACATCAGTAAAATGGAGCAGAAAAAGAATCCGCAAGCGGTGCTTGATGTGCTCAAC
TGGTTCGACAATAGTTCAAAGCAACGGCCTAGTTCCAAATATATGACACCTGCAGTGCAT
CACAACACCAATACAACTCATT
>g11190.t4 Gene=g11190 Length=147
MSSDEDKPPAPPIRLTSNRSGSDRLDGPPPDLKPLPKEPDDPDRKKKTLKNKIKSTKSHN
DSKPNISYPTNFEHTVHVGFDAITGEFTGMPEQWAVLLMNSNISKMEQKKNPQAVLDVLN
WFDNSSKQRPSSKYMTPAVHHNTNTTH
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g11190.t4 | CDD | cd01093 | CRIB_PAK_like | 64 | 109 | 2.95932E-23 |
| 8 | g11190.t4 | Gene3D | G3DSA:3.90.810.10 | - | 61 | 140 | 3.0E-31 |
| 6 | g11190.t4 | MobiDBLite | mobidb-lite | consensus disorder prediction | 1 | 68 | - |
| 7 | g11190.t4 | MobiDBLite | mobidb-lite | consensus disorder prediction | 30 | 59 | - |
| 5 | g11190.t4 | MobiDBLite | mobidb-lite | consensus disorder prediction | 126 | 147 | - |
| 2 | g11190.t4 | PANTHER | PTHR45832 | - | 5 | 136 | 2.4E-37 |
| 3 | g11190.t4 | PANTHER | PTHR45832:SF10 | NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE | 5 | 136 | 2.4E-37 |
| 1 | g11190.t4 | Pfam | PF00786 | P21-Rho-binding domain | 66 | 120 | 4.7E-23 |
| 9 | g11190.t4 | ProSiteProfiles | PS50108 | CRIB domain profile. | 66 | 79 | 9.933 |
| 4 | g11190.t4 | SMART | SM00285 | PBD_5 | 66 | 101 | 3.2E-13 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004674 | protein serine/threonine kinase activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed