General information for g11197.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Beta carbonic anhydrase 1.
Parent gene
- The parent gene g11197 is located on chr_1: 14516305..14522998 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11197 | g11197.t1 | TSS | g11197.t1 | 14515626 | 14515626 |
| chr_1 | g11197 | g11197.t1 | isoform | g11197.t1 | 14515917 | 14516892 |
| chr_1 | g11197 | g11197.t1 | exon | g11197.t1.exon1 | 14515917 | 14516019 |
| chr_1 | g11197 | g11197.t1 | cds | g11197.t1.CDS1 | 14515917 | 14516019 |
| chr_1 | g11197 | g11197.t1 | exon | g11197.t1.exon2 | 14516091 | 14516249 |
| chr_1 | g11197 | g11197.t1 | cds | g11197.t1.CDS2 | 14516091 | 14516249 |
| chr_1 | g11197 | g11197.t1 | exon | g11197.t1.exon3 | 14516308 | 14516499 |
| chr_1 | g11197 | g11197.t1 | cds | g11197.t1.CDS3 | 14516308 | 14516499 |
| chr_1 | g11197 | g11197.t1 | exon | g11197.t1.exon4 | 14516579 | 14516892 |
| chr_1 | g11197 | g11197.t1 | cds | g11197.t1.CDS4 | 14516579 | 14516892 |
| chr_1 | g11197 | g11197.t1 | TTS | g11197.t1 | 14517081 | 14517081 |
Sequences
>g11197.t1 Gene=g11197 Length=768
ATGGAACGAATTTTAAGAGGAATTATGAGATATCGGAATACAACAAGAGCAGCGATGGTG
AAAGAATTTGAGCAAGTTAGAGATAATCCGCAACCAAAGGCATTCTTCTTCACTTGTATG
GATTCTCGAATGATACCAACAAGGTTTACTGACACACACGTTGGAGACATGTTTGTTGTA
AGAAATGCTGGCAATCTTGTACCTCATAGTCACTTTTTTCAAGATGAATATTTCTCATGC
GAACCAGCTGCTCTTGAATTAGGTTGTGTTGTGAATAATATTCGTCACGTTATTGTGTGT
GGTCATAGTGACTGTAAAGCAATCAATCTTCTTCATCAACTTCAATGTACTCAGTTTGCA
TCAAGAAAGAATCGTAGACTCTCTCCTCTTCGAAGCTGGCTAGCAACGCATGCTTCTACA
AGTCTTGAAAAATTCCAGTATCTTTCCGAGCATGGATTTGACAAACCATTAATGTTCACT
GCCGAAACACCACTTCGAAAATTTGTTGCTTACATCGACCCAGATAATAAATTTGCAATT
GAAGATAAATTGTCACAGATTAATACATTACAACAGCTACAGAATATTGCCAGTTATGGT
TTTCTTAAGAAACGTTTAGAGCAATTTGATTTGCACATTCATGCACTTTGGTTTGATATC
TATACTGGTGATATTTATTATTTCAGTAGACAAATGAAGAGATTTGTAATCATATCAGAA
GAAACAATCGATAAAATCAGTGAAGATGTAAAGAAATATTACTCATGA
>g11197.t1 Gene=g11197 Length=255
MERILRGIMRYRNTTRAAMVKEFEQVRDNPQPKAFFFTCMDSRMIPTRFTDTHVGDMFVV
RNAGNLVPHSHFFQDEYFSCEPAALELGCVVNNIRHVIVCGHSDCKAINLLHQLQCTQFA
SRKNRRLSPLRSWLATHASTSLEKFQYLSEHGFDKPLMFTAETPLRKFVAYIDPDNKFAI
EDKLSQINTLQQLQNIASYGFLKKRLEQFDLHIHALWFDIYTGDIYYFSRQMKRFVIISE
ETIDKISEDVKKYYS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g11197.t1 | Gene3D | G3DSA:3.40.1050.10 | - | 1 | 238 | 0 |
| 2 | g11197.t1 | PANTHER | PTHR11002:SF69 | CARBONIC ANHYDRASE | 1 | 253 | 0 |
| 3 | g11197.t1 | PANTHER | PTHR11002 | CARBONIC ANHYDRASE | 1 | 253 | 0 |
| 1 | g11197.t1 | Pfam | PF00484 | Carbonic anhydrase | 35 | 224 | 0 |
| 5 | g11197.t1 | SMART | SM00947 | Pro_CA_2 | 27 | 229 | 0 |
| 4 | g11197.t1 | SUPERFAMILY | SSF53056 | beta-carbonic anhydrase, cab | 1 | 251 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008270 | zinc ion binding | MF |
| GO:0004089 | carbonate dehydratase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K01673 (carbonic anhydrase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
