General information for g11233.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Monocarboxylate transporter 10.
Parent gene
- The parent gene g11233 is located on chr_1: 14836143..14838469 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11233 | g11233.t3 | isoform | g11233.t3 | 14836143 | 14838469 |
| chr_1 | g11233 | g11233.t3 | exon | g11233.t3.exon1 | 14836143 | 14836534 |
| chr_1 | g11233 | g11233.t3 | cds | g11233.t3.CDS1 | 14836144 | 14836534 |
| chr_1 | g11233 | g11233.t3 | exon | g11233.t3.exon2 | 14836596 | 14836779 |
| chr_1 | g11233 | g11233.t3 | cds | g11233.t3.CDS2 | 14836596 | 14836779 |
| chr_1 | g11233 | g11233.t3 | exon | g11233.t3.exon3 | 14837863 | 14838469 |
| chr_1 | g11233 | g11233.t3 | cds | g11233.t3.CDS3 | 14837863 | 14838127 |
| chr_1 | g11233 | g11233.t3 | TSS | g11233.t3 | 14838469 | 14838469 |
| chr_1 | g11233 | g11233.t3 | TTS | g11233.t3 | NA | NA |
Sequences
>g11233.t3 Gene=g11233 Length=1183
AGTTGAGTTTGAGCGATCATTCAGTTCACACATATTGCATATTTACACGAGGAAATACGG
AAAAAAGACATTCTAGTAGGAAAAATCTTTCTTTGAGAGCTCACAAGCAAGAGAAGTGTA
AAAGTCAATAATAAAAAATTGAGTGTCAACAAATGTGTGATTGAACTTTTTAAATAAATC
TCTCTTATCAGTTTATCATCAACTCGGACCTCGTGTTTTATTGTGCCATATTTTTTAAAA
ATTTAAGATATATAAATAGAAAAACAACGTGTCATAAAAAGGAAATATATAAACACAATA
TAACTTGTATTTTAAACAAAGAAAAGATATTTTCTCAATAAAATGACTTCAGAATCGCTA
ATAAATAATAATAATAATGTAATAATAGTATCAGCTGATAAAAATATAGTTAAAGAGGAA
GATACCAGAAAAGTTGTTGAACATGAGCCTCCTGATTCAGGCTTTCGTGCTTACATAGTT
GCAATATGTGCTTTTCTCTGTAATGGAATAATTTTTGGCATTATAAATACTTATTCAGTT
ATTTATCTGAGTTTACAAAAACAACTCGTTGCAAGTGGAGATGATGCAAATGCATCGTCA
AAAGCTGCACTTGTAGGCTCGTTGACAATTGGCGCTACATTTTTCTTTTCACCAGTATCT
GGTATCTTAGTTGACAAGTTAGGGTTAAGAAGAACAACATTTCTTGGCGGTATTTTAACA
ACATGCGGTATGATGCTTTCTGCGTATCACACAGATGATCCTTTTCAGCCAGAAAAGGTT
ACTGTTCTCTGTTTTACTTATGGCTTACTTTTTGGAACTGGTGCAGCTTTGGCATATACT
CCCACATTAGCAATATTGGGACATTATTTTAAAAAGAAGCTGGGAATCGTTAATGGTTTT
GTGACAGCTGGTAGCAATGTTTTTACATTCATTTTACCACAATTCTTGACTCATATTGAG
GAACATTATGGTTTAAAAAACTGCTTACGAGTGATGATGATCATGTCAAGTTTCATCATT
GTTTGTGCTCTTATTTACAAACCTTTGCAGCCACCTCCACCAAAAAAGCAACAGAAAGCC
AATCGATCAAGTTTCTACAATTTTCTTCGATCGATAATTAACTTTGATAACTGGAAAAAG
AAGAAATATGTCGTGTGGGCAATATCGATTCCCGTAGCTTTAT
>g11233.t3 Gene=g11233 Length=280
MTSESLINNNNNVIIVSADKNIVKEEDTRKVVEHEPPDSGFRAYIVAICAFLCNGIIFGI
INTYSVIYLSLQKQLVASGDDANASSKAALVGSLTIGATFFFSPVSGILVDKLGLRRTTF
LGGILTTCGMMLSAYHTDDPFQPEKVTVLCFTYGLLFGTGAALAYTPTLAILGHYFKKKL
GIVNGFVTAGSNVFTFILPQFLTHIEEHYGLKNCLRVMMIMSSFIIVCALIYKPLQPPPP
KKQQKANRSSFYNFLRSIINFDNWKKKKYVVWAISIPVAL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g11233.t3 | Gene3D | G3DSA:1.20.1250.20 | MFS general substrate transporter like domains | 25 | 277 | 5.4E-23 |
| 2 | g11233.t3 | PANTHER | PTHR11360:SF119 | MONOCARBOXYLATE TRANSPORTER 10 | 27 | 280 | 2.5E-53 |
| 3 | g11233.t3 | PANTHER | PTHR11360 | MONOCARBOXYLATE TRANSPORTER | 27 | 280 | 2.5E-53 |
| 1 | g11233.t3 | Pfam | PF07690 | Major Facilitator Superfamily | 48 | 258 | 1.4E-18 |
| 18 | g11233.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 42 | - |
| 24 | g11233.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 43 | 67 | - |
| 14 | g11233.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 68 | 87 | - |
| 21 | g11233.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 88 | 109 | - |
| 17 | g11233.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 110 | 114 | - |
| 25 | g11233.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 115 | 134 | - |
| 13 | g11233.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 135 | 145 | - |
| 22 | g11233.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 146 | 176 | - |
| 19 | g11233.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 177 | 181 | - |
| 20 | g11233.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 182 | 202 | - |
| 15 | g11233.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 203 | 213 | - |
| 23 | g11233.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 214 | 232 | - |
| 16 | g11233.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 233 | 280 | - |
| 12 | g11233.t3 | ProSiteProfiles | PS50850 | Major facilitator superfamily (MFS) profile. | 43 | 280 | 8.804 |
| 10 | g11233.t3 | SUPERFAMILY | SSF103473 | MFS general substrate transporter | 32 | 256 | 4.05E-26 |
| 7 | g11233.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 46 | 68 | - |
| 9 | g11233.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 88 | 110 | - |
| 4 | g11233.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 119 | 136 | - |
| 5 | g11233.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 151 | 173 | - |
| 6 | g11233.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 180 | 202 | - |
| 8 | g11233.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 217 | 235 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0055085 | transmembrane transport | BP |
| GO:0015349 | thyroid hormone transmembrane transporter activity | MF |
| GO:0005887 | integral component of plasma membrane | CC |
| GO:0015173 | aromatic amino acid transmembrane transporter activity | MF |
| GO:0022857 | transmembrane transporter activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
