General information for g11257.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as hypothetical.
Parent gene
- The parent gene g11257 is located on chr_1: 15129768..15131274 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11257 | g11257.t1 | isoform | g11257.t1 | 15129768 | 15131274 |
| chr_1 | g11257 | g11257.t1 | exon | g11257.t1.exon1 | 15129768 | 15129860 |
| chr_1 | g11257 | g11257.t1 | cds | g11257.t1.CDS1 | 15129768 | 15129860 |
| chr_1 | g11257 | g11257.t1 | exon | g11257.t1.exon2 | 15129912 | 15130045 |
| chr_1 | g11257 | g11257.t1 | cds | g11257.t1.CDS2 | 15129912 | 15130045 |
| chr_1 | g11257 | g11257.t1 | exon | g11257.t1.exon3 | 15130129 | 15130365 |
| chr_1 | g11257 | g11257.t1 | cds | g11257.t1.CDS3 | 15130129 | 15130365 |
| chr_1 | g11257 | g11257.t1 | exon | g11257.t1.exon4 | 15130416 | 15131274 |
| chr_1 | g11257 | g11257.t1 | cds | g11257.t1.CDS4 | 15130416 | 15131274 |
| chr_1 | g11257 | g11257.t1 | TSS | g11257.t1 | NA | NA |
| chr_1 | g11257 | g11257.t1 | TTS | g11257.t1 | NA | NA |
Sequences
>g11257.t1 Gene=g11257 Length=1323
ATGATAGCTTGTGGCTGGCTTATTAAAGGAATCAATGAAAAATTGCCAGACAGTCGAGTT
ATGATATATGATAGCGTTTCATTTAATGACAATGTTACTTTTCCTGCTTTGACAATCATA
CCTGAAGTTTTTCATTTAAAAAAGACATTTTTTGAAATAAATAGTATTTCATTATCTATG
CGGAATGGCTTCACATTATTACCAAGTACTATTGATCAAATTTGTAGCTTCGTCATTAGA
AACAAATTCTGTTCTGTTATCAATTTAATTAATTTTCAAACCGACAAATGTGGGTACTTG
ATTGCAAAATATGCCAGAAAAACTTCTGTAGCTGCATGGTTTGAAGAACAGTTTTCTCTT
TGGAATAATGAAATTAAATTAAACTTTTCTGAAATTCGAACAGTTTTTGGAATGGGTTAT
TCACTAAATTTGATTAAAGCTGAAAAATTATTTAATTCAAATGAAATTGACAATGAACTT
TTGTACAAGTCAAATATTAGACCGAAACATCCTGTTAAAAATACTTCAAGATTAATTAAA
AATTTTTATCCAATCACAACTAAAGCAGGTGATCGTCCAAAATTGAAAATAAAATTTAGT
CAACAAGATTTCAACAGTAGCAATTTTGAAAGATGTAATTTTCCAAAAGTTCTTGTTCAT
CATCCAACTTTGAGTCCAACATTCATAGATCGTGATGAATTTATTGATATAAATTTTGGA
GAAACAATGAACATAGAATTGAATGTTGTAATAATAAGAACAGACAAAAATCTTAAGAAA
CTTAAATCTGTTGAGCGAGGTTGTTATTTTGATAATGAATTTCAATTAAAGTTTTTTAAA
ACTTATACACAAAAAAATTGTGAAATTGAATGTTTTACAAACATTACTATAAAAGAATGT
GGTTGTGTTTCACATTTGATGCCGTATAATGCTATTAAAAATATCATAATTTGTCAAAAT
GAATATCAAACATTTTATGAAAGTTGTCTTTATCAAACAACTTCAAAATTGCTAATATCA
ATACACTTTTCAACAGAACAAAATTGTTCTTGCTTACCACTATGCAATTCAGTTAGTTAT
TATGCAAAATATAATTCTTTAAAAAATGAAAACAAAGAAGCATCCATAAAAATGATACTA
AATATTGACAACATTGTAGCATACAGAAGATATCAACAATTTTCATTTCATGACATTATT
TCATACGTAGGTGGATTATTAGGTCTTTTTGTAGGTGTTTCTGTGCTCTCTATTGTAGAA
ATTTTCTACTTCATCATATCAAAATCATTTGTCCGCATATGTAGTTCTTTAAGGGCACAA
TAA
>g11257.t1 Gene=g11257 Length=440
MIACGWLIKGINEKLPDSRVMIYDSVSFNDNVTFPALTIIPEVFHLKKTFFEINSISLSM
RNGFTLLPSTIDQICSFVIRNKFCSVINLINFQTDKCGYLIAKYARKTSVAAWFEEQFSL
WNNEIKLNFSEIRTVFGMGYSLNLIKAEKLFNSNEIDNELLYKSNIRPKHPVKNTSRLIK
NFYPITTKAGDRPKLKIKFSQQDFNSSNFERCNFPKVLVHHPTLSPTFIDRDEFIDINFG
ETMNIELNVVIIRTDKNLKKLKSVERGCYFDNEFQLKFFKTYTQKNCEIECFTNITIKEC
GCVSHLMPYNAIKNIIICQNEYQTFYESCLYQTTSKLLISIHFSTEQNCSCLPLCNSVSY
YAKYNSLKNENKEASIKMILNIDNIVAYRRYQQFSFHDIISYVGGLLGLFVGVSVLSIVE
IFYFIISKSFVRICSSLRAQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 4 | g11257.t1 | Gene3D | G3DSA:2.60.470.10 | - | 216 | 392 | 1.3E-23 |
| 5 | g11257.t1 | Gene3D | G3DSA:1.10.287.820 | - | 260 | 355 | 1.3E-23 |
| 6 | g11257.t1 | Gene3D | G3DSA:1.10.287.770 | - | 393 | 422 | 1.3E-23 |
| 2 | g11257.t1 | PANTHER | PTHR11690 | AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED | 21 | 434 | 5.3E-27 |
| 1 | g11257.t1 | Pfam | PF00858 | Amiloride-sensitive sodium channel | 2 | 424 | 8.4E-37 |
| 8 | g11257.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 398 | - |
| 9 | g11257.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 399 | 426 | - |
| 7 | g11257.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 427 | 440 | - |
| 3 | g11257.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 404 | 426 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0005272 | sodium channel activity | MF |
| GO:0006814 | sodium ion transport | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed