General information for g11257.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as hypothetical.
Parent gene
- The parent gene g11257 is located on chr_1: 15129768..15131274 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11257 | g11257.t2 | isoform | g11257.t2 | 15127631 | 15131274 |
| chr_1 | g11257 | g11257.t2 | exon | g11257.t2.exon1 | 15127631 | 15127759 |
| chr_1 | g11257 | g11257.t2 | cds | g11257.t2.CDS1 | 15127631 | 15127759 |
| chr_1 | g11257 | g11257.t2 | exon | g11257.t2.exon2 | 15127825 | 15128051 |
| chr_1 | g11257 | g11257.t2 | cds | g11257.t2.CDS2 | 15127825 | 15128051 |
| chr_1 | g11257 | g11257.t2 | exon | g11257.t2.exon3 | 15128103 | 15128486 |
| chr_1 | g11257 | g11257.t2 | cds | g11257.t2.CDS3 | 15128103 | 15128486 |
| chr_1 | g11257 | g11257.t2 | exon | g11257.t2.exon4 | 15128543 | 15128600 |
| chr_1 | g11257 | g11257.t2 | cds | g11257.t2.CDS4 | 15128543 | 15128600 |
| chr_1 | g11257 | g11257.t2 | exon | g11257.t2.exon5 | 15128660 | 15128817 |
| chr_1 | g11257 | g11257.t2 | cds | g11257.t2.CDS5 | 15128660 | 15128817 |
| chr_1 | g11257 | g11257.t2 | exon | g11257.t2.exon6 | 15129320 | 15129676 |
| chr_1 | g11257 | g11257.t2 | cds | g11257.t2.CDS6 | 15129320 | 15129676 |
| chr_1 | g11257 | g11257.t2 | exon | g11257.t2.exon7 | 15129737 | 15129860 |
| chr_1 | g11257 | g11257.t2 | cds | g11257.t2.CDS7 | 15129737 | 15129860 |
| chr_1 | g11257 | g11257.t2 | exon | g11257.t2.exon8 | 15129912 | 15130045 |
| chr_1 | g11257 | g11257.t2 | cds | g11257.t2.CDS8 | 15129912 | 15130045 |
| chr_1 | g11257 | g11257.t2 | exon | g11257.t2.exon9 | 15130129 | 15130365 |
| chr_1 | g11257 | g11257.t2 | cds | g11257.t2.CDS9 | 15130129 | 15130365 |
| chr_1 | g11257 | g11257.t2 | exon | g11257.t2.exon10 | 15130416 | 15131274 |
| chr_1 | g11257 | g11257.t2 | cds | g11257.t2.CDS10 | 15130416 | 15131274 |
| chr_1 | g11257 | g11257.t2 | TSS | g11257.t2 | NA | NA |
| chr_1 | g11257 | g11257.t2 | TTS | g11257.t2 | NA | NA |
Sequences
>g11257.t2 Gene=g11257 Length=2667
ATGTTTTGGACAATTTGCATGATTACATCAGTGATTTTAACATCAATTCTAATAAAAAAT
CTTGTAGTAAAAATTATGAATTTTCCTATTGTCGTGTATTTATCAGAAAAACCAGTTCCA
ATGTCAAAGATAAATTTTCCTGCAGTCACAATATGTCCTGGCATGCTATTAATTCCGTTT
GAATTCCATCCTTTTAAACGTCATACAATTACAGAAAGTCGTTCTCCTTTTAAAACTCAA
AGATATGAAAATGATGATTTACGTGGGGATGACGATAAATTGCGATTTCAATTTTATGAA
GCTTTAAATAAATTAGATAAAGATGGATATAATATCACCAAAATCAATATGCATACACTA
AAACGAATTCATGCAATGGATCTGGTAACAAGAAATGGATTATTTGAAAGACTTAATTAC
TCAATTTCTACTGAAGATTTCTTAGACGTCATGAATGAATTTGAAAAATTTACAAAAGTT
TTAGTTAATTTTCAATTATTTTGGCTTGAAAATTTTTCTGACGAGTTATCAGAAATTATC
ACAGAAAATGGTTTTTGCTACACTTTTAATATGGCAAATCACACGGAAGTTTTAAACAGT
GAAATTGTTTCAAGTGATTTTCATTACCTACATAAAACACTTGAAGGTGAAAATCCTATA
ATTGCATATAATTATCCTTTGAAAACTTCACAAATTAATGGATTTAGAGCTAAAATGCAG
CACTATACTAACATGAATAATCACTGGTTATCAAACAATAATTGTAAATGGTGTGATATG
ATCAAAAAAACTTCTTTTAATTTTGATGGTGTATTGATTTTGATTCATGATTCTTACGAA
TTGCCATCATCAAATATGCTCAAATTATTTGTAACAAGCAGTAAGAAAATGGACATTTTT
ATTGAGCCAGAAGTTTTAACAATTGATGATTCGATGAAAAGTTTGAAAACTGAAAGAGAA
ACAACAGAAACTTTCAAACAGGAACAAAGTTCAGAATTAAGTTTTCATGTAAAATACCAA
CAAAACCACTGCAATGAATTTATAAAAAAGCAACAATTTGATGAAATTGACTTTTTATCT
TTTATTGGAGGACTTTTAAATTTATTTACTGGATTTTCATTTATTTCATTTATTGAAATT
TTTTACTGGTTCATTTATCGTACAATAACAAAATCATGTTTTGTTTGGAAATCTAATAGA
GTTCGTCCCTTTAGTACTGAGTCAAAGAAATCAGAAAAATTGATACAAAAATTTTTTCAA
GAATCTTCGATTCATAGTTTTGTTTATTGGACAAAGTCAACAATTTTTGACAAACTATTT
TGGATCCCTATTTTTTTACTTTCAATGATAGCTTGTGGCTGGCTTATTAAAGGAATCAAT
GAAAAATTGCCAGACAGTCGAGTTATGATATATGATAGCGTTTCATTTAATGACAATGTT
ACTTTTCCTGCTTTGACAATCATACCTGAAGTTTTTCATTTAAAAAAGACATTTTTTGAA
ATAAATAGTATTTCATTATCTATGCGGAATGGCTTCACATTATTACCAAGTACTATTGAT
CAAATTTGTAGCTTCGTCATTAGAAACAAATTCTGTTCTGTTATCAATTTAATTAATTTT
CAAACCGACAAATGTGGGTACTTGATTGCAAAATATGCCAGAAAAACTTCTGTAGCTGCA
TGGTTTGAAGAACAGTTTTCTCTTTGGAATAATGAAATTAAATTAAACTTTTCTGAAATT
CGAACAGTTTTTGGAATGGGTTATTCACTAAATTTGATTAAAGCTGAAAAATTATTTAAT
TCAAATGAAATTGACAATGAACTTTTGTACAAGTCAAATATTAGACCGAAACATCCTGTT
AAAAATACTTCAAGATTAATTAAAAATTTTTATCCAATCACAACTAAAGCAGGTGATCGT
CCAAAATTGAAAATAAAATTTAGTCAACAAGATTTCAACAGTAGCAATTTTGAAAGATGT
AATTTTCCAAAAGTTCTTGTTCATCATCCAACTTTGAGTCCAACATTCATAGATCGTGAT
GAATTTATTGATATAAATTTTGGAGAAACAATGAACATAGAATTGAATGTTGTAATAATA
AGAACAGACAAAAATCTTAAGAAACTTAAATCTGTTGAGCGAGGTTGTTATTTTGATAAT
GAATTTCAATTAAAGTTTTTTAAAACTTATACACAAAAAAATTGTGAAATTGAATGTTTT
ACAAACATTACTATAAAAGAATGTGGTTGTGTTTCACATTTGATGCCGTATAATGCTATT
AAAAATATCATAATTTGTCAAAATGAATATCAAACATTTTATGAAAGTTGTCTTTATCAA
ACAACTTCAAAATTGCTAATATCAATACACTTTTCAACAGAACAAAATTGTTCTTGCTTA
CCACTATGCAATTCAGTTAGTTATTATGCAAAATATAATTCTTTAAAAAATGAAAACAAA
GAAGCATCCATAAAAATGATACTAAATATTGACAACATTGTAGCATACAGAAGATATCAA
CAATTTTCATTTCATGACATTATTTCATACGTAGGTGGATTATTAGGTCTTTTTGTAGGT
GTTTCTGTGCTCTCTATTGTAGAAATTTTCTACTTCATCATATCAAAATCATTTGTCCGC
ATATGTAGTTCTTTAAGGGCACAATAA
>g11257.t2 Gene=g11257 Length=888
MFWTICMITSVILTSILIKNLVVKIMNFPIVVYLSEKPVPMSKINFPAVTICPGMLLIPF
EFHPFKRHTITESRSPFKTQRYENDDLRGDDDKLRFQFYEALNKLDKDGYNITKINMHTL
KRIHAMDLVTRNGLFERLNYSISTEDFLDVMNEFEKFTKVLVNFQLFWLENFSDELSEII
TENGFCYTFNMANHTEVLNSEIVSSDFHYLHKTLEGENPIIAYNYPLKTSQINGFRAKMQ
HYTNMNNHWLSNNNCKWCDMIKKTSFNFDGVLILIHDSYELPSSNMLKLFVTSSKKMDIF
IEPEVLTIDDSMKSLKTERETTETFKQEQSSELSFHVKYQQNHCNEFIKKQQFDEIDFLS
FIGGLLNLFTGFSFISFIEIFYWFIYRTITKSCFVWKSNRVRPFSTESKKSEKLIQKFFQ
ESSIHSFVYWTKSTIFDKLFWIPIFLLSMIACGWLIKGINEKLPDSRVMIYDSVSFNDNV
TFPALTIIPEVFHLKKTFFEINSISLSMRNGFTLLPSTIDQICSFVIRNKFCSVINLINF
QTDKCGYLIAKYARKTSVAAWFEEQFSLWNNEIKLNFSEIRTVFGMGYSLNLIKAEKLFN
SNEIDNELLYKSNIRPKHPVKNTSRLIKNFYPITTKAGDRPKLKIKFSQQDFNSSNFERC
NFPKVLVHHPTLSPTFIDRDEFIDINFGETMNIELNVVIIRTDKNLKKLKSVERGCYFDN
EFQLKFFKTYTQKNCEIECFTNITIKECGCVSHLMPYNAIKNIIICQNEYQTFYESCLYQ
TTSKLLISIHFSTEQNCSCLPLCNSVSYYAKYNSLKNENKEASIKMILNIDNIVAYRRYQ
QFSFHDIISYVGGLLGLFVGVSVLSIVEIFYFIISKSFVRICSSLRAQ
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 19 | g11257.t2 | Gene3D | G3DSA:1.10.287.770 | - | 1 | 29 | 2.7E-7 |
| 14 | g11257.t2 | Gene3D | G3DSA:2.60.470.10 | - | 30 | 313 | 2.7E-7 |
| 15 | g11257.t2 | Gene3D | G3DSA:1.10.3590.10 | - | 63 | 270 | 2.7E-7 |
| 16 | g11257.t2 | Gene3D | G3DSA:1.10.287.820 | - | 314 | 351 | 2.7E-7 |
| 13 | g11257.t2 | Gene3D | G3DSA:2.60.470.10 | - | 664 | 840 | 4.3E-23 |
| 17 | g11257.t2 | Gene3D | G3DSA:1.10.287.820 | - | 708 | 803 | 4.3E-23 |
| 18 | g11257.t2 | Gene3D | G3DSA:1.10.287.770 | - | 841 | 870 | 4.3E-23 |
| 6 | g11257.t2 | PANTHER | PTHR11690:SF222 | ACID-SENSING ION CHANNEL 5 | 2 | 344 | 1.4E-53 |
| 9 | g11257.t2 | PANTHER | PTHR11690 | AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED | 2 | 344 | 1.4E-53 |
| 4 | g11257.t2 | PANTHER | PTHR11690:SF222 | ACID-SENSING ION CHANNEL 5 | 319 | 391 | 1.4E-53 |
| 7 | g11257.t2 | PANTHER | PTHR11690 | AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED | 319 | 391 | 1.4E-53 |
| 5 | g11257.t2 | PANTHER | PTHR11690:SF222 | ACID-SENSING ION CHANNEL 5 | 406 | 878 | 1.4E-53 |
| 8 | g11257.t2 | PANTHER | PTHR11690 | AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED | 406 | 878 | 1.4E-53 |
| 2 | g11257.t2 | Pfam | PF00858 | Amiloride-sensitive sodium channel | 1 | 307 | 3.8E-15 |
| 1 | g11257.t2 | Pfam | PF00858 | Amiloride-sensitive sodium channel | 320 | 382 | 5.3E-9 |
| 3 | g11257.t2 | Pfam | PF00858 | Amiloride-sensitive sodium channel | 418 | 872 | 3.7E-43 |
| 20 | g11257.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 11 | - |
| 28 | g11257.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 12 | 34 | - |
| 23 | g11257.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 35 | 45 | - |
| 30 | g11257.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 46 | 65 | - |
| 21 | g11257.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 66 | 357 | - |
| 29 | g11257.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 358 | 385 | - |
| 25 | g11257.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 386 | 438 | - |
| 27 | g11257.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 439 | 459 | - |
| 22 | g11257.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 460 | 846 | - |
| 26 | g11257.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 847 | 874 | - |
| 24 | g11257.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 875 | 888 | - |
| 11 | g11257.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 363 | 385 | - |
| 12 | g11257.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 439 | 456 | - |
| 10 | g11257.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 852 | 874 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0005272 | sodium channel activity | MF |
| GO:0006814 | sodium ion transport | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed