Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Chymotrypsin-2.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g11269 g11269.t14 TSS g11269.t14 15274498 15274498
chr_1 g11269 g11269.t14 isoform g11269.t14 15274515 15277320
chr_1 g11269 g11269.t14 exon g11269.t14.exon1 15274515 15274569
chr_1 g11269 g11269.t14 cds g11269.t14.CDS1 15274515 15274569
chr_1 g11269 g11269.t14 exon g11269.t14.exon2 15274626 15274667
chr_1 g11269 g11269.t14 cds g11269.t14.CDS2 15274626 15274667
chr_1 g11269 g11269.t14 exon g11269.t14.exon3 15275270 15275380
chr_1 g11269 g11269.t14 cds g11269.t14.CDS3 15275270 15275380
chr_1 g11269 g11269.t14 exon g11269.t14.exon4 15275451 15275595
chr_1 g11269 g11269.t14 cds g11269.t14.CDS4 15275451 15275595
chr_1 g11269 g11269.t14 exon g11269.t14.exon5 15275672 15275784
chr_1 g11269 g11269.t14 cds g11269.t14.CDS5 15275672 15275784
chr_1 g11269 g11269.t14 exon g11269.t14.exon6 15276455 15276601
chr_1 g11269 g11269.t14 cds g11269.t14.CDS6 15276455 15276601
chr_1 g11269 g11269.t14 exon g11269.t14.exon7 15276659 15276692
chr_1 g11269 g11269.t14 cds g11269.t14.CDS7 15276659 15276692
chr_1 g11269 g11269.t14 exon g11269.t14.exon8 15276848 15276899
chr_1 g11269 g11269.t14 cds g11269.t14.CDS8 15276848 15276899
chr_1 g11269 g11269.t14 exon g11269.t14.exon9 15277264 15277320
chr_1 g11269 g11269.t14 cds g11269.t14.CDS9 15277264 15277320
chr_1 g11269 g11269.t14 TTS g11269.t14 15277409 15277409

Sequences

>g11269.t14 Gene=g11269 Length=756
ATGATTCGTCAAGTATTTTTATTAGTGACATTGGCAGTTGCTGCCTTTGCAGGACCCCTT
TCTGATAGATTCTTGAATGGAAGAATTGTTGGTGGTGCTCCAGCAGTTGATGGACAATTC
CCATATCAAGTTTCTCTTCGTACATTCCCTGCACTGGGACATTTCTGTGGTGGATCAATT
ATTCAAGAACATTGGGTTCTTTCAGCAGCTCATTGCACAATCAACCGCACACCTGCCAAT
ACCCGTGTCGTTGCTGGTACAGTTCTTCTTAATGGTGGCGCAAATCCTCAACTTCATGAT
GTCGAGAGAATTGTCAATCATCCAAACTACGATTCAGCCTTAATTGCTCAAGACGTTTGC
GTCATTCGAGTGACAAGTCCGTTCATATTCACGGCAAATGTTCGTGCTATTCCTTATGCC
AGTCACTTTACTGGTGGTGGTGTTGATGCCGTTGTTTCAGGATGGGGCGGCACAGCTGTC
ACTGGTGGACCTGCACCAAACAACTTACAATGGATCAGAAAAACAACGCTTACAAATGCT
GATTGCCGTGCTCGTATGGGTACTGCTAATGAACGATTTGTTATTGACAGTAAAATTTGC
ACATTCACACAAGCTGGACAAGGAATCTGTCAAGGAGACTCAGGCGGTCCATTAACTGCA
GGTGGATATGTCATTGGTATTGTTAGCTGGAATATTCCTGATGGATATGATCGTGTTTCA
TACTGGCACAGTTGGATTACTCAAAACATCAGTTAA

>g11269.t14 Gene=g11269 Length=251
MIRQVFLLVTLAVAAFAGPLSDRFLNGRIVGGAPAVDGQFPYQVSLRTFPALGHFCGGSI
IQEHWVLSAAHCTINRTPANTRVVAGTVLLNGGANPQLHDVERIVNHPNYDSALIAQDVC
VIRVTSPFIFTANVRAIPYASHFTGGGVDAVVSGWGGTAVTGGPAPNNLQWIRKTTLTNA
DCRARMGTANERFVIDSKICTFTQAGQGICQGDSGGPLTAGGYVIGIVSWNIPDGYDRVS
YWHSWITQNIS

Protein features from InterProScan

Transcript Database ID Name Start End E.value
15 g11269.t14 CDD cd00190 Tryp_SPc 29 249 4.2662E-64
9 g11269.t14 Gene3D G3DSA:2.40.10.10 - 22 251 2.5E-53
2 g11269.t14 PANTHER PTHR24276 POLYSERASE-RELATED 1 250 1.1E-51
3 g11269.t14 PANTHER PTHR24276:SF78 AT20289P-RELATED 1 250 1.1E-51
6 g11269.t14 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 57 72 4.1E-12
5 g11269.t14 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 114 128 4.1E-12
4 g11269.t14 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 207 219 4.1E-12
1 g11269.t14 Pfam PF00089 Trypsin 29 245 3.3E-46
11 g11269.t14 Phobius SIGNAL_PEPTIDE Signal peptide region 1 17 -
12 g11269.t14 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide. 1 4 -
13 g11269.t14 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide. 5 13 -
14 g11269.t14 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide. 14 17 -
10 g11269.t14 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 18 251 -
17 g11269.t14 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 67 72 -
18 g11269.t14 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 208 219 -
19 g11269.t14 ProSiteProfiles PS50240 Serine proteases, trypsin domain profile. 29 251 27.287
16 g11269.t14 SMART SM00020 trypsin_2 28 246 5.4E-57
7 g11269.t14 SUPERFAMILY SSF50494 Trypsin-like serine proteases 5 250 1.98E-63
8 g11269.t14 SignalP_EUK SignalP-noTM SignalP-noTM 1 17 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0004252 serine-type endopeptidase activity MF
GO:0006508 proteolysis BP

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed