General information for g11269.t50
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Chymotrypsin-2.
Parent gene
- The parent gene g11269 is located on chr_1: 15275568..15277541 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11269 | g11269.t50 | TSS | g11269.t50 | 15274498 | 15274498 |
| chr_1 | g11269 | g11269.t50 | isoform | g11269.t50 | 15274515 | 15277413 |
| chr_1 | g11269 | g11269.t50 | exon | g11269.t50.exon1 | 15274515 | 15274569 |
| chr_1 | g11269 | g11269.t50 | exon | g11269.t50.exon2 | 15274626 | 15274671 |
| chr_1 | g11269 | g11269.t50 | cds | g11269.t50.CDS1 | 15274647 | 15274671 |
| chr_1 | g11269 | g11269.t50 | exon | g11269.t50.exon3 | 15275270 | 15275380 |
| chr_1 | g11269 | g11269.t50 | cds | g11269.t50.CDS2 | 15275270 | 15275380 |
| chr_1 | g11269 | g11269.t50 | exon | g11269.t50.exon4 | 15275451 | 15275595 |
| chr_1 | g11269 | g11269.t50 | cds | g11269.t50.CDS3 | 15275451 | 15275595 |
| chr_1 | g11269 | g11269.t50 | exon | g11269.t50.exon5 | 15275672 | 15275784 |
| chr_1 | g11269 | g11269.t50 | cds | g11269.t50.CDS4 | 15275672 | 15275784 |
| chr_1 | g11269 | g11269.t50 | exon | g11269.t50.exon6 | 15276455 | 15276601 |
| chr_1 | g11269 | g11269.t50 | cds | g11269.t50.CDS5 | 15276455 | 15276601 |
| chr_1 | g11269 | g11269.t50 | exon | g11269.t50.exon7 | 15276659 | 15276692 |
| chr_1 | g11269 | g11269.t50 | cds | g11269.t50.CDS6 | 15276659 | 15276692 |
| chr_1 | g11269 | g11269.t50 | exon | g11269.t50.exon8 | 15276848 | 15276903 |
| chr_1 | g11269 | g11269.t50 | cds | g11269.t50.CDS7 | 15276848 | 15276903 |
| chr_1 | g11269 | g11269.t50 | exon | g11269.t50.exon9 | 15277264 | 15277413 |
| chr_1 | g11269 | g11269.t50 | cds | g11269.t50.CDS8 | 15277264 | 15277274 |
| chr_1 | g11269 | g11269.t50 | TTS | g11269.t50 | 15277409 | 15277409 |
Sequences
>g11269.t50 Gene=g11269 Length=857
ATGATTCGTCAAGTATTTTTATTAGTGACATTGGCAGTTGCTGCCTTTGCAGGACCCCTT
TCTGATAGATTCTTGAATGGAAGAATTGTTGGTGGTGGTAACTCCAGCAGTTGATGGACA
ATTCCCATATCAAGTTTCTCTTCGTACATTCCCTGCACTGGGACATTTCTGTGGTGGATC
AATTATTCAAGAACATTGGGTTCTTTCAGCAGCTCATTGCACAATCAACCGCACACCTGC
CAATACCCGTGTCGTTGCTGGTACAGTTCTTCTTAATGGTGGCGCAAATCCTCAACTTCA
TGATGTCGAGAGAATTGTCAATCATCCAAACTACGATTCAGCCTTAATTGCTCAAGACGT
TTGCGTCATTCGAGTGACAAGTCCGTTCATATTCACGGCAAATGTTCGTGCTATTCCTTA
TGCCAGTCACTTTACTGGTGGTGGTGTTGATGCCGTTGTTTCAGGATGGGGCGGCACAGC
TGTCACTGGTGGACCTGCACCAAACAACTTACAATGGATCAGAAAAACAACGCTTACAAA
TGCTGATTGCCGTGCTCGTATGGGTACTGCTAATGAACGATTTGTTATTGACAGTAAAAT
TTGCACATTCACACAAGCTGGACAAGGAATCTGTCAAGGAGACTCAGGCGGTCCATTAAC
TGCAGGTGGATATGTCATTGGTATTGTTAGCTGGAATATTCCTGTAAGATGGATATGATC
GTGTTTCATACTGGCACAGTTGGATTACTCAAAACATCAGTTAAATGGCTACATTTATTG
CAATTATCATCCAGAAATTTGATGCTGTATTTTAAATCAATTCATTTTGAATAAATTTTT
ATTTGCAAAATTTAAAA
>g11269.t50 Gene=g11269 Length=213
MEELLVVVTPAVDGQFPYQVSLRTFPALGHFCGGSIIQEHWVLSAAHCTINRTPANTRVV
AGTVLLNGGANPQLHDVERIVNHPNYDSALIAQDVCVIRVTSPFIFTANVRAIPYASHFT
GGGVDAVVSGWGGTAVTGGPAPNNLQWIRKTTLTNADCRARMGTANERFVIDSKICTFTQ
AGQGICQGDSGGPLTAGGYVIGIVSWNIPVRWI
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g11269.t50 | CDD | cd00190 | Tryp_SPc | 9 | 206 | 9.49077E-57 |
| 8 | g11269.t50 | Gene3D | G3DSA:2.40.10.10 | - | 10 | 208 | 2.7E-48 |
| 9 | g11269.t50 | Gene3D | G3DSA:2.40.10.10 | - | 17 | 112 | 2.7E-48 |
| 2 | g11269.t50 | PANTHER | PTHR24276 | POLYSERASE-RELATED | 14 | 207 | 4.7E-43 |
| 3 | g11269.t50 | PANTHER | PTHR24276:SF78 | AT20289P-RELATED | 14 | 207 | 4.7E-43 |
| 4 | g11269.t50 | PRINTS | PR00722 | Chymotrypsin serine protease family (S1) signature | 33 | 48 | 2.8E-12 |
| 6 | g11269.t50 | PRINTS | PR00722 | Chymotrypsin serine protease family (S1) signature | 90 | 104 | 2.8E-12 |
| 5 | g11269.t50 | PRINTS | PR00722 | Chymotrypsin serine protease family (S1) signature | 183 | 195 | 2.8E-12 |
| 1 | g11269.t50 | Pfam | PF00089 | Trypsin | 8 | 207 | 4.2E-44 |
| 11 | g11269.t50 | ProSitePatterns | PS00134 | Serine proteases, trypsin family, histidine active site. | 43 | 48 | - |
| 12 | g11269.t50 | ProSitePatterns | PS00135 | Serine proteases, trypsin family, serine active site. | 184 | 195 | - |
| 14 | g11269.t50 | ProSiteProfiles | PS50240 | Serine proteases, trypsin domain profile. | 5 | 213 | 23.123 |
| 13 | g11269.t50 | SMART | SM00020 | trypsin_2 | 5 | 213 | 2.9E-45 |
| 7 | g11269.t50 | SUPERFAMILY | SSF50494 | Trypsin-like serine proteases | 10 | 209 | 4.57E-53 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004252 | serine-type endopeptidase activity | MF |
| GO:0006508 | proteolysis | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed