General information for g11293.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Proteasome subunit beta type-5.
Parent gene
- The parent gene g11293 is located on chr_1: 15468246..15471815 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11293 | g11293.t1 | TTS | g11293.t1 | 15467253 | 15467253 |
| chr_1 | g11293 | g11293.t1 | isoform | g11293.t1 | 15467315 | 15468246 |
| chr_1 | g11293 | g11293.t1 | exon | g11293.t1.exon1 | 15467315 | 15467472 |
| chr_1 | g11293 | g11293.t1 | cds | g11293.t1.CDS1 | 15467315 | 15467472 |
| chr_1 | g11293 | g11293.t1 | exon | g11293.t1.exon2 | 15467533 | 15468058 |
| chr_1 | g11293 | g11293.t1 | cds | g11293.t1.CDS2 | 15467533 | 15468058 |
| chr_1 | g11293 | g11293.t1 | exon | g11293.t1.exon3 | 15468115 | 15468246 |
| chr_1 | g11293 | g11293.t1 | cds | g11293.t1.CDS3 | 15468115 | 15468246 |
| chr_1 | g11293 | g11293.t1 | TSS | g11293.t1 | 15468344 | 15468344 |
Sequences
>g11293.t1 Gene=g11293 Length=816
ATGGCTCTTAATGATATATTGAAGCATATGCCTTCCGTTGGCGATATGTTAAGCGATTAC
AAATCTACTGAAGAAATGGATTTCATCAATTTATCTCAAAATAAAGTTCTCAGTGCTCCA
CCGTATAGTAATCCTGTTGAAAATCTTGCTAAATTGCATGAAAACAATGATAATATAAAG
ATCAATTTTGACCATGGAACAACTACACTCGGATTCATTTATCAAGGAGGAGTAGTATTG
GCTGTTGACAGTAGAGCAACTGGAGGTCAATATATTGGATCACAATCAGTTCGTAAAGTT
GTTGAAATTAATGATTTATTGCTTGGCACACTCGCTGGAGGTGCAGCTGATTGCACATAT
TGGTATAGAGTTCTCACAAGTGAATGTCGTTTATATGAATTGCGAAATAAGAAGAAAATT
TCATTAGCTGCTGCTACAAAAATTATGAATAACATCATCTATTCGTATAAAAACTCTGGT
CTCAGCATGGGAATGATCTTAGCTGGTGGTGACATGAATCAAGTTAGCTTATATTATTTA
GATTCAGATGGCACAAGAACTATGGGAAAAGTGTTTTCTGTTGGTAGCGGTTCAATTTTT
GCATATGGTGTTTTAGATTCTGGATATAAATGGGAATTAACTGATGAACAAGCATATGAA
TTGGGACGTCGTTCGATTTATCATGCAACTCATCGTGATGCTTATTCTGGTGGCACTGTT
CGAGTTTATCATGTAAAGAAAGATGGATGGAATTTGATTTCAGAGGAAGACTGCTTGGAT
CTTCATCGTCGCTATGAAGCAGAGAAGAAGAAATAA
>g11293.t1 Gene=g11293 Length=271
MALNDILKHMPSVGDMLSDYKSTEEMDFINLSQNKVLSAPPYSNPVENLAKLHENNDNIK
INFDHGTTTLGFIYQGGVVLAVDSRATGGQYIGSQSVRKVVEINDLLLGTLAGGAADCTY
WYRVLTSECRLYELRNKKKISLAAATKIMNNIIYSYKNSGLSMGMILAGGDMNQVSLYYL
DSDGTRTMGKVFSVGSGSIFAYGVLDSGYKWELTDEQAYELGRRSIYHATHRDAYSGGTV
RVYHVKKDGWNLISEEDCLDLHRRYEAEKKK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g11293.t1 | CDD | cd03761 | proteasome_beta_type_5 | 67 | 254 | 2.83071E-119 |
| 9 | g11293.t1 | Gene3D | G3DSA:3.60.20.10 | Glutamine Phosphoribosylpyrophosphate | 67 | 271 | 1.1E-78 |
| 2 | g11293.t1 | PANTHER | PTHR11599:SF63 | PROTEASOME SUBUNIT BETA | 56 | 262 | 3.0E-84 |
| 3 | g11293.t1 | PANTHER | PTHR11599 | PROTEASOME SUBUNIT ALPHA/BETA | 56 | 262 | 3.0E-84 |
| 6 | g11293.t1 | PRINTS | PR00141 | Proteasome component signature | 74 | 89 | 4.5E-19 |
| 7 | g11293.t1 | PRINTS | PR00141 | Proteasome component signature | 195 | 206 | 4.5E-19 |
| 5 | g11293.t1 | PRINTS | PR00141 | Proteasome component signature | 206 | 217 | 4.5E-19 |
| 4 | g11293.t1 | PRINTS | PR00141 | Proteasome component signature | 231 | 242 | 4.5E-19 |
| 1 | g11293.t1 | Pfam | PF00227 | Proteasome subunit | 64 | 245 | 5.8E-44 |
| 11 | g11293.t1 | ProSitePatterns | PS00854 | Proteasome beta-type subunits signature. | 70 | 117 | - |
| 12 | g11293.t1 | ProSiteProfiles | PS51476 | Proteasome beta-type subunit profile. | 66 | 245 | 47.724 |
| 8 | g11293.t1 | SUPERFAMILY | SSF56235 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 45 | 265 | 2.44E-64 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0051603 | proteolysis involved in cellular protein catabolic process | BP |
| GO:0004298 | threonine-type endopeptidase activity | MF |
| GO:0005839 | proteasome core complex | CC |
KEGG
Orthology
- This transcript has been annotated with K02737 (20S proteasome subunit beta 5)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
