General information for g11340.t8
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Charged multivesicular body protein 2a.
Parent gene
- The parent gene g11340 is located on chr_1: 15727827..15729772 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11340 | g11340.t8 | TTS | g11340.t8 | 15727669 | 15727669 |
| chr_1 | g11340 | g11340.t8 | isoform | g11340.t8 | 15727827 | 15728593 |
| chr_1 | g11340 | g11340.t8 | exon | g11340.t8.exon1 | 15727827 | 15728474 |
| chr_1 | g11340 | g11340.t8 | cds | g11340.t8.CDS1 | 15727827 | 15728474 |
| chr_1 | g11340 | g11340.t8 | exon | g11340.t8.exon2 | 15728543 | 15728593 |
| chr_1 | g11340 | g11340.t8 | cds | g11340.t8.CDS2 | 15728543 | 15728593 |
| chr_1 | g11340 | g11340.t8 | TSS | g11340.t8 | 15728694 | 15728694 |
Sequences
>g11340.t8 Gene=g11340 Length=699
ATGGAGTGGCTTTTTGGTAAAAAGATGACACCCGATGAAATGCTTAGAAAGAAGAATCAA
AGAGCCTTGAACAAAGCAATGCGAGATCTTGATCGAGAAAAAATGAAAATGGAACAACAG
GAAAAGAAAGTCATTGCTGATATTAAAAAACTTGCAAAAGAAAATCAAATGGATGCAGTA
AAAATAATGGCAAAGGATCTTGTGCGAACCAGAAGGCAAGTTAGAAAATTTATGTTGATG
AAGGCAAACATCCAGGCAGTTTCTCTCAAAATTCAAACACTCAAATCACAAAACACAATG
GCTCAAGCTATGAAAGGTGTGAGTCGTGCAATGATGAATATGAATAGACAAATGAATATG
CCACAGATACAACAAATTCTTCATGAATTCGAAAAACAATCTGAAATAATGGACATGAAA
GAAGAAATGATTAATGATGTTATTGATGATGCAATGGAAGATGAGGGAGATGAGGAAGAA
ACTGACGCCGTTGTGTCACAAGTTTTAGATGAATTAGGTCTCCAATTAAATGATCAGCTA
TCAGGACTACCGCAAGCATCTGGATCACTTTCCGTCGTTGGTCAAAAACAACCTCAGGCA
GCTGCTGTTGCTGCTGGTGGTGGAGCTGCCGCTGGTGGCAATTCACCCGATGCTGATGAT
GAACTTCAAAAGCGCCTTGATAATTTGCGTCGAGAATAA
>g11340.t8 Gene=g11340 Length=232
MEWLFGKKMTPDEMLRKKNQRALNKAMRDLDREKMKMEQQEKKVIADIKKLAKENQMDAV
KIMAKDLVRTRRQVRKFMLMKANIQAVSLKIQTLKSQNTMAQAMKGVSRAMMNMNRQMNM
PQIQQILHEFEKQSEIMDMKEEMINDVIDDAMEDEGDEEETDAVVSQVLDELGLQLNDQL
SGLPQASGSLSVVGQKQPQAAAVAAGGGAAAGGNSPDADDELQKRLDNLRRE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g11340.t8 | Coils | Coil | Coil | 20 | 54 | - |
| 5 | g11340.t8 | MobiDBLite | mobidb-lite | consensus disorder prediction | 191 | 232 | - |
| 4 | g11340.t8 | MobiDBLite | mobidb-lite | consensus disorder prediction | 218 | 232 | - |
| 2 | g11340.t8 | PANTHER | PTHR10476:SF4 | CHARGED MULTIVESICULAR BODY PROTEIN 2A | 1 | 231 | 1.7E-81 |
| 3 | g11340.t8 | PANTHER | PTHR10476 | CHARGED MULTIVESICULAR BODY PROTEIN | 1 | 231 | 1.7E-81 |
| 1 | g11340.t8 | Pfam | PF03357 | Snf7 | 19 | 186 | 1.1E-40 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0007034 | vacuolar transport | BP |
KEGG
Orthology
- This transcript has been annotated with K12191 (charged multivesicular body protein 2A)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
