General information for g11347.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Arylsulfatase B.
Parent gene
- The parent gene g11347 is located on chr_1: 15740135..15742966 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11347 | g11347.t2 | TSS | g11347.t2 | 15739088 | 15739088 |
| chr_1 | g11347 | g11347.t2 | isoform | g11347.t2 | 15739155 | 15740259 |
| chr_1 | g11347 | g11347.t2 | exon | g11347.t2.exon1 | 15739155 | 15739348 |
| chr_1 | g11347 | g11347.t2 | cds | g11347.t2.CDS1 | 15739155 | 15739348 |
| chr_1 | g11347 | g11347.t2 | exon | g11347.t2.exon2 | 15739412 | 15739482 |
| chr_1 | g11347 | g11347.t2 | cds | g11347.t2.CDS2 | 15739412 | 15739482 |
| chr_1 | g11347 | g11347.t2 | exon | g11347.t2.exon3 | 15739560 | 15740138 |
| chr_1 | g11347 | g11347.t2 | cds | g11347.t2.CDS3 | 15739560 | 15740138 |
| chr_1 | g11347 | g11347.t2 | exon | g11347.t2.exon4 | 15740183 | 15740259 |
| chr_1 | g11347 | g11347.t2 | cds | g11347.t2.CDS4 | 15740183 | 15740205 |
| chr_1 | g11347 | g11347.t2 | TTS | g11347.t2 | NA | NA |
Sequences
>g11347.t2 Gene=g11347 Length=921
ATGATTACTAAAGTATCAAATTTTTTCTTATTTATAAGTTATTTGCTGTTCAGTGTTATC
AAGTGTGAGAAACCAAACATTGTTATAATACTAGCTGATGATTTAGGCTATAATGATGTG
AGCTTTCATGGCAGTTCAGAAATTCCCACACCGAATTTGGATGCTCTTTGCTATAATGGA
GTTATCCTTAACAGATTTTATACAACGCCTCTATGTACACCTTCGCGAAGTTCATTAATG
ACAGGAAAATACAGTACAAAATTAGGCATGAACCATTACGTGATACCAAGTGATGAGCCA
TGGGGACTTCCCTTGAATGAAAAAATCATTCCAGAATATTTTAAAGAAGCTGGTTATAAA
ACTGCACTTATTGGCAAATGGCATCTTGGATTTTTCAAAAAATCTTATACGCCTCTTATG
CGAGGTTTTGATTATCATTATGGTTATCTTGGTCCATATATTGGTTATTATGACCATTCA
CTCATCATGCTTGATAGAAATTATTCACGTGGATTTGATATGCGAAATAATTTTGAAGTT
GAAAATGTTAGAGGAAAATATGCGACAGATGTATTCACCGATGAAGCTGTTAATTTAATT
AAGAGACATAACACAAGCGATCCTCTTTTTTTGCTTTTATCACATTTAGCACCACATGCT
GGCAATGAAGATAAGCCACTTGAAGCATCTGAAGAAGTTATAAATAAGTTCGCTTATATA
AAAAACGAACAGAGAAGAACGTTGGCGGCAATGATTAATATTATGGATGACGGAATTGGT
AGGGTTGTGGAGGCATTGAACGAAAAAGGCATCATGAACAATACGATAATTATGTTTCTA
TCAGAAACTTTAATTTTTACAAGATAACGGTGGACCAACTTTTGGAATTCACTCAACAGA
AGCATCAAATTCTCCTTTAAG
>g11347.t2 Gene=g11347 Length=288
MITKVSNFFLFISYLLFSVIKCEKPNIVIILADDLGYNDVSFHGSSEIPTPNLDALCYNG
VILNRFYTTPLCTPSRSSLMTGKYSTKLGMNHYVIPSDEPWGLPLNEKIIPEYFKEAGYK
TALIGKWHLGFFKKSYTPLMRGFDYHYGYLGPYIGYYDHSLIMLDRNYSRGFDMRNNFEV
ENVRGKYATDVFTDEAVNLIKRHNTSDPLFLLLSHLAPHAGNEDKPLEASEEVINKFAYI
KNEQRRTLAAMINIMDDGIGRVVEALNEKGIMNNTIIMFLSETLIFTR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 12 | g11347.t2 | CDD | cd16029 | 4-S | 25 | 281 | 5.99795E-137 |
| 6 | g11347.t2 | Gene3D | G3DSA:3.40.720.10 | Alkaline Phosphatase | 23 | 282 | 4.9E-86 |
| 2 | g11347.t2 | PANTHER | PTHR10342 | ARYLSULFATASE | 21 | 282 | 7.2E-129 |
| 3 | g11347.t2 | PANTHER | PTHR10342:SF264 | MIP05773P | 21 | 282 | 7.2E-129 |
| 1 | g11347.t2 | Pfam | PF00884 | Sulfatase | 25 | 281 | 1.7E-56 |
| 8 | g11347.t2 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 22 | - |
| 9 | g11347.t2 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 7 | - |
| 10 | g11347.t2 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 8 | 17 | - |
| 11 | g11347.t2 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 18 | 22 | - |
| 7 | g11347.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 23 | 288 | - |
| 13 | g11347.t2 | ProSitePatterns | PS00523 | Sulfatases signature 1. | 70 | 82 | - |
| 14 | g11347.t2 | ProSitePatterns | PS00149 | Sulfatases signature 2. | 118 | 128 | - |
| 4 | g11347.t2 | SUPERFAMILY | SSF53649 | Alkaline phosphatase-like | 23 | 281 | 2.47E-82 |
| 5 | g11347.t2 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 22 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008484 | sulfuric ester hydrolase activity | MF |
| GO:0003824 | catalytic activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
