General information for g11349.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Kinesin light chain.
Parent gene
- The parent gene g11349 is located on chr_1: 15748279..15750291 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11349 | g11349.t1 | isoform | g11349.t1 | 15746707 | 15749367 |
| chr_1 | g11349 | g11349.t1 | exon | g11349.t1.exon1 | 15746707 | 15746853 |
| chr_1 | g11349 | g11349.t1 | cds | g11349.t1.CDS1 | 15746707 | 15746853 |
| chr_1 | g11349 | g11349.t1 | exon | g11349.t1.exon2 | 15746934 | 15747137 |
| chr_1 | g11349 | g11349.t1 | cds | g11349.t1.CDS2 | 15746934 | 15747137 |
| chr_1 | g11349 | g11349.t1 | exon | g11349.t1.exon3 | 15747990 | 15748217 |
| chr_1 | g11349 | g11349.t1 | cds | g11349.t1.CDS3 | 15747990 | 15748217 |
| chr_1 | g11349 | g11349.t1 | exon | g11349.t1.exon4 | 15748277 | 15749068 |
| chr_1 | g11349 | g11349.t1 | cds | g11349.t1.CDS4 | 15748277 | 15749068 |
| chr_1 | g11349 | g11349.t1 | exon | g11349.t1.exon5 | 15749182 | 15749367 |
| chr_1 | g11349 | g11349.t1 | cds | g11349.t1.CDS5 | 15749182 | 15749367 |
| chr_1 | g11349 | g11349.t1 | TSS | g11349.t1 | NA | NA |
| chr_1 | g11349 | g11349.t1 | TTS | g11349.t1 | NA | NA |
Sequences
>g11349.t1 Gene=g11349 Length=1557
ATGACACAAATGACCCAAGAAGAAATTGTCACAAACACAAAGACGGTCTTGCAGGGACTT
GAAGCACTACGACATGAACACATGTCAATTATGTCTGGTCTCACTGAAGGCAAAAAAGAT
CCAGACAAAGTAGACATTATCCAAAAAAATATTGAAAACATTGAATTGGGTTTAGGTGAA
GCTCAGGTCATTGTAGTGTTAGCGTCACATTTACAAAATATTGAAGCCGAAAAACAGAAA
TTACGGACACAAGTTCGGCGTCTGTGTCAAGAAAATGCATGGCTTCGAGATGAATTAGCA
AATACACAACAAAAATTGCAAACATCAGAGCAAATGGTGGCACAACTTGAAGAAGAGAAA
AAACATCTTGATTTTATGCAATCTGTACGCAAATATGATGAAAATCAAGACGAGATTAAT
GAAAATGAAAAGTCACGTACTGATCCAGTCGTTGAATTGTTTCCTGAAGATGAACAAGAA
GATCGCAACAATATGTCGCCTACACCACCAAGTCAATTTGCAAATCAAGCTAATGCCGGT
TATGAAATTCCAGCTCGTCTTAGAACACTTCATAATCTCGTTATTCAATATGCATCGCAA
GGGCGTTATGAGGTAGCAGTACCATTGTGCAAACAAGCACTTGAAGATCTTGAAAAAACT
AGTGGACATGATCATCCAGATGTGGCAACAATGCTCAACATTCTCGCATTAGTTTATCGT
GATCAAAACAAATATAAGGAAGCAGCCAATTTATTAAATGATGCTCTTACAATTCGAGAG
AAAACGCTTGGCGAAAATCATCCAGCAGTTGCTGCAACTCTTAATAATTTGGCTGTCTTA
TATGGAAAGCGTGGCAAATATAAAGATGCAGAGCCACTATGCAAACGTGCATTAGAAATT
CGAGAAAAAGTTCTTGGCAAAGATCATCCAGATGTTGCAAAGCAATTAAATAATTTGGCA
TTATTGTGTCAAAATCAAGGAAAATATGAAGAAGTTGAGCTTTACTATCAGAGAGCATTA
GAAATTTATGAGCATAAACTTGGACCAGATGATCCAAATGTTGCAAAAACGAAAAATAAT
TTAGCAAGCTGCTATCTTAAGCAGGGTAAATACAAGGAAGCTGAAATTCTTTACAAGCAA
GTGTTGACACGTGCACATGAACGAGAATTTGGAACAATTGATGGTGATAATAAGCCAATT
TGGCAGGTTGCGGAAGAGCGTGAAGAAAATAAACATCGAAATCGTGAAAATACACCGTAC
GGTGAATATGGCGGTTGGCATAAAGCGGCAAAAGTTGATTCACCGACAGTAACGACAACG
CTCAAAAACTTGGGTGCACTTTATCGACGACAAGGAAAATATGAAGCGGCTGAGACATTG
GAGGACTGCGCAATGCGATCAAAGCGAGAAGCGCTAGACTTAGTGAAACAAACTAAAGTG
GCACAAATACTGGCGAGTGATGATAAACGACGATCTCGTACTGTTCGTGGACCATCAGGT
GATGGTGATCAATATGAGGGCATTGAAGATGCAAACCGTCGTTTATCGAAATCATAA
>g11349.t1 Gene=g11349 Length=518
MTQMTQEEIVTNTKTVLQGLEALRHEHMSIMSGLTEGKKDPDKVDIIQKNIENIELGLGE
AQVIVVLASHLQNIEAEKQKLRTQVRRLCQENAWLRDELANTQQKLQTSEQMVAQLEEEK
KHLDFMQSVRKYDENQDEINENEKSRTDPVVELFPEDEQEDRNNMSPTPPSQFANQANAG
YEIPARLRTLHNLVIQYASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYR
DQNKYKEAANLLNDALTIREKTLGENHPAVAATLNNLAVLYGKRGKYKDAEPLCKRALEI
REKVLGKDHPDVAKQLNNLALLCQNQGKYEEVELYYQRALEIYEHKLGPDDPNVAKTKNN
LASCYLKQGKYKEAEILYKQVLTRAHEREFGTIDGDNKPIWQVAEEREENKHRNRENTPY
GEYGGWHKAAKVDSPTVTTTLKNLGALYRRQGKYEAAETLEDCAMRSKREALDLVKQTKV
AQILASDDKRRSRTVRGPSGDGDQYEGIEDANRRLSKS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g11349.t1 | Coils | Coil | Coil | 64 | 119 | - |
| 15 | g11349.t1 | Gene3D | G3DSA:1.25.40.10 | - | 170 | 471 | 1.7E-149 |
| 23 | g11349.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 484 | 518 | - |
| 5 | g11349.t1 | PANTHER | PTHR45783 | KINESIN LIGHT CHAIN | 3 | 494 | 5.3E-254 |
| 6 | g11349.t1 | PANTHER | PTHR45783:SF7 | KINESIN LIGHT CHAIN 1 | 3 | 494 | 5.3E-254 |
| 7 | g11349.t1 | PRINTS | PR00381 | Kinesin light chain signature | 83 | 100 | 9.0E-73 |
| 12 | g11349.t1 | PRINTS | PR00381 | Kinesin light chain signature | 180 | 199 | 9.0E-73 |
| 11 | g11349.t1 | PRINTS | PR00381 | Kinesin light chain signature | 202 | 220 | 9.0E-73 |
| 10 | g11349.t1 | PRINTS | PR00381 | Kinesin light chain signature | 267 | 284 | 9.0E-73 |
| 8 | g11349.t1 | PRINTS | PR00381 | Kinesin light chain signature | 311 | 331 | 9.0E-73 |
| 9 | g11349.t1 | PRINTS | PR00381 | Kinesin light chain signature | 346 | 367 | 9.0E-73 |
| 1 | g11349.t1 | Pfam | PF13424 | Tetratricopeptide repeat | 187 | 261 | 5.1E-17 |
| 2 | g11349.t1 | Pfam | PF13424 | Tetratricopeptide repeat | 270 | 344 | 6.3E-20 |
| 3 | g11349.t1 | Pfam | PF13374 | Tetratricopeptide repeat | 354 | 392 | 2.3E-5 |
| 4 | g11349.t1 | Pfam | PF13374 | Tetratricopeptide repeat | 439 | 469 | 8.3E-4 |
| 22 | g11349.t1 | ProSitePatterns | PS01160 | Kinesin light chain repeat. | 338 | 379 | - |
| 27 | g11349.t1 | ProSiteProfiles | PS50005 | TPR repeat profile. | 187 | 220 | 5.281 |
| 30 | g11349.t1 | ProSiteProfiles | PS50293 | TPR repeat region circular profile. | 187 | 388 | 20.343 |
| 25 | g11349.t1 | ProSiteProfiles | PS50005 | TPR repeat profile. | 229 | 262 | 8.378 |
| 24 | g11349.t1 | ProSiteProfiles | PS50005 | TPR repeat profile. | 271 | 304 | 7.906 |
| 29 | g11349.t1 | ProSiteProfiles | PS50005 | TPR repeat profile. | 313 | 346 | 7.788 |
| 26 | g11349.t1 | ProSiteProfiles | PS50005 | TPR repeat profile. | 355 | 388 | 7.788 |
| 28 | g11349.t1 | ProSiteProfiles | PS50005 | TPR repeat profile. | 438 | 471 | 6.49 |
| 31 | g11349.t1 | ProSiteProfiles | PS50293 | TPR repeat region circular profile. | 438 | 471 | 7.172 |
| 18 | g11349.t1 | SMART | SM00028 | tpr_5 | 229 | 262 | 0.24 |
| 17 | g11349.t1 | SMART | SM00028 | tpr_5 | 271 | 304 | 3.2E-5 |
| 21 | g11349.t1 | SMART | SM00028 | tpr_5 | 313 | 346 | 0.0023 |
| 19 | g11349.t1 | SMART | SM00028 | tpr_5 | 355 | 388 | 3.5E-4 |
| 20 | g11349.t1 | SMART | SM00028 | tpr_5 | 438 | 471 | 38.0 |
| 13 | g11349.t1 | SUPERFAMILY | SSF48452 | TPR-like | 187 | 302 | 1.14E-23 |
| 14 | g11349.t1 | SUPERFAMILY | SSF48452 | TPR-like | 265 | 457 | 4.62E-30 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
| GO:0005871 | kinesin complex | CC |
KEGG
Orthology
- This transcript has been annotated with K10407 (kinesin light chain)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
