General information for g11362.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as 85/88 kDa calcium-independent phospholipase A2.
Parent gene
- The parent gene g11362 is located on chr_1: 15804956..15806209 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11362 | g11362.t1 | TTS | g11362.t1 | 15801832 | 15801832 |
| chr_1 | g11362 | g11362.t1 | isoform | g11362.t1 | 15802377 | 15806209 |
| chr_1 | g11362 | g11362.t1 | exon | g11362.t1.exon1 | 15802377 | 15802535 |
| chr_1 | g11362 | g11362.t1 | cds | g11362.t1.CDS1 | 15802377 | 15802535 |
| chr_1 | g11362 | g11362.t1 | exon | g11362.t1.exon2 | 15802601 | 15802644 |
| chr_1 | g11362 | g11362.t1 | cds | g11362.t1.CDS2 | 15802601 | 15802644 |
| chr_1 | g11362 | g11362.t1 | exon | g11362.t1.exon3 | 15802707 | 15802848 |
| chr_1 | g11362 | g11362.t1 | cds | g11362.t1.CDS3 | 15802707 | 15802848 |
| chr_1 | g11362 | g11362.t1 | exon | g11362.t1.exon4 | 15802933 | 15803033 |
| chr_1 | g11362 | g11362.t1 | cds | g11362.t1.CDS4 | 15802933 | 15803033 |
| chr_1 | g11362 | g11362.t1 | exon | g11362.t1.exon5 | 15803102 | 15803158 |
| chr_1 | g11362 | g11362.t1 | cds | g11362.t1.CDS5 | 15803102 | 15803158 |
| chr_1 | g11362 | g11362.t1 | exon | g11362.t1.exon6 | 15803216 | 15803251 |
| chr_1 | g11362 | g11362.t1 | cds | g11362.t1.CDS6 | 15803216 | 15803251 |
| chr_1 | g11362 | g11362.t1 | exon | g11362.t1.exon7 | 15803322 | 15803418 |
| chr_1 | g11362 | g11362.t1 | cds | g11362.t1.CDS7 | 15803322 | 15803418 |
| chr_1 | g11362 | g11362.t1 | exon | g11362.t1.exon8 | 15803484 | 15803683 |
| chr_1 | g11362 | g11362.t1 | cds | g11362.t1.CDS8 | 15803484 | 15803683 |
| chr_1 | g11362 | g11362.t1 | exon | g11362.t1.exon9 | 15803747 | 15803869 |
| chr_1 | g11362 | g11362.t1 | cds | g11362.t1.CDS9 | 15803747 | 15803869 |
| chr_1 | g11362 | g11362.t1 | exon | g11362.t1.exon10 | 15803927 | 15804393 |
| chr_1 | g11362 | g11362.t1 | cds | g11362.t1.CDS10 | 15803927 | 15804393 |
| chr_1 | g11362 | g11362.t1 | exon | g11362.t1.exon11 | 15804448 | 15804877 |
| chr_1 | g11362 | g11362.t1 | cds | g11362.t1.CDS11 | 15804448 | 15804877 |
| chr_1 | g11362 | g11362.t1 | exon | g11362.t1.exon12 | 15804947 | 15805548 |
| chr_1 | g11362 | g11362.t1 | cds | g11362.t1.CDS12 | 15804947 | 15805548 |
| chr_1 | g11362 | g11362.t1 | exon | g11362.t1.exon13 | 15805647 | 15805869 |
| chr_1 | g11362 | g11362.t1 | cds | g11362.t1.CDS13 | 15805647 | 15805869 |
| chr_1 | g11362 | g11362.t1 | exon | g11362.t1.exon14 | 15806200 | 15806209 |
| chr_1 | g11362 | g11362.t1 | cds | g11362.t1.CDS14 | 15806200 | 15806209 |
| chr_1 | g11362 | g11362.t1 | TSS | g11362.t1 | 15806364 | 15806364 |
Sequences
>g11362.t1 Gene=g11362 Length=2691
ATGTTTAGCGCCATTAAAAATTTATTGACGGGAGAGATCCCTCCAAGCAAAGTCATAGAG
AAAAGTTTAGATTCTATTGCAAGCTACAATGTTTTACAACGAGATGATTGCATGCTTCTG
TTTGCTCCACAAATAACCGATAATTCTACATCAAACACATCAAGTAAAAGTAAAAAGTTT
TACGAAATAATCCTCTATCGTCCTGCATCAGAGTCAATAAATTCATCTTATAGTTTATTT
CGTGCAGAAACACAGGAAGAAGCTTTGGCACGTTTTGAAGCTTATACCCATCGAGTACCC
AATTTTGTTACAATGGTTAATCAATACTATAATATTCCTGGATTACAAAAAGTTTGCGAT
CTTTTAACGGAAAATCCTTCATGGTCGATTGCACACTTGGTTGCATACTTTAATCTTACT
GAGTATTTATCGAATCCAGCTGTCGCAGAACTAATTGACTATCCTGATCATGTGAAATAT
ATGACACCACTTCAAGTTGCAATTAAAGCTAAAAATATTGAGGTTGTCAAAGGATTATTG
AACGTAACGAAATTAGATCATTTAGACTATAACAGCAATGGTATCTTTCATTACGCAGCA
AACACATCAAAAGAAATGATAAATATCTTGACTAGTAAGAGTTTAGTAAATTTAAATCAT
ATCAATTTAGATGGCATTACTCCACTACATCATGCTTGTTTAAGCAACAATCCTGATTGT
GTCAATGCATTGGTATGTGCGGGAGCTGATGTTAACATCTCCGCAAAACACGTTAATGGA
AGTGGAAAAGGGGGAAACAAATTGCAAAATAGAAATGCTCCTTCTACTACTACAAGTCCA
TCAGGAACTGTTGCAGAATTCTTTCAAACAAATGCTAATAAAGTATGTCGAGAGGAAATG
AAAAATGGCGGAACACCATTGCATTGGGCGAGTTCTCGAGAAGTTCTTGAAGTTCTTATT
GAAAGAGGATGTCATATAGATAGTCTTGATTTTAATGGACGATCTGCTCTGCATGTTATG
GTTTTAAAAAATCAACTAGATTGTGTTGTCTCATTATTAGCTCATGAAGCAGAAATTGAT
TTAAAGGATAAAGACGGCAACACACCACTTCATATTGCCGTTGAGAAAAAGTTTATACCA
ATTGTACAATGTTTAGTAGTTTTTGGATGTGACATTAATATGAAAAACAAAAATGACCAA
ACGGCTCGACACATGGTTGGAAAAGAAGCATCAGGTTCAAATGATGACATGATTCTCTAT
ATTTTACATTCTGTTGGTGCAAAACGATGTCCTGATACTTCTACACGATGTCCAGTCGGT
TGCAATGCAAAAGGTACATACAACGGAATTCCTCCTGCACAACCAGAAACAACGGAACAA
AGAGAAGCGATTCAACAAATGCTTGCAACAACAACATCTCAACTCATGAGAGGTAGAAAT
AGCGTGCCTACTATAGCAAATCAACAATTATTTCGTTTACCAAAAGAACAACCAGTACTT
ATTGATACAACTGCTGAACAAAAGGGCCAAAGTGTAATGGATGCTTTATTGGGAATGTTT
ACGTCAAAAATCCAAGCGGCAGCAAAAAAAGAAGTGCCAGTATGTGACAAAGGAACGTCT
ACAGCAGAAGATGAAAATGTAGAAGTTATGGAAGAAGACCATGAATGTAGTGCAAGTGAA
GAAGATTCTGTAAATTCTGGCAGTCGGGGCCGTTTATTATGTCTTGATGGAGGCGGTATA
AGAGGACTCGTATTAGTGCAAATGCTTTTAGAAATTGAACAACTATCGCAAACACCAATT
CATTTTCTATTTGATTGGATCGCAGGAACTTCAACTGGCGGAATATTAGCTTTAGGAATT
GGTTCAGGGAAAACAATGAAACAATGCATGTGTCTTTATTTAAAAATGAAAAATGTCGCT
TTCAATGGCAGTCGTCCTTACTCAAGCGATCCACTAGAAAATGTTTTAAAGGAAAATTTA
GGAGAGCACACTGTAATGGCAGAAATTCAACATCCAAAAATAATGGTATCTGCTGTAATG
GCTGATAGGAAGCCGGTGGACTTGCACTTTTTTAGAAATTATAAGACAGCATCTGACATT
CTTAATATTGCAACCCCAACATCAAACAGACGCATACCACCACCAAGTCCAGAAAATCAA
CTGATTTGGCGAGCAGCAAGAGCCACAGGTGCTGCTCCTTCCTATTTTCGTGCTTTTGGT
CGTTTTCTTGATGGTGGTCTGATTGCAAACAATCCTACACTTGATGCTATGACAGAAATA
CATGAATACAATATGGCATTATATAGTGTTAATCGTAAAAATGAAGCAGTTCCATTGTCA
ATAGTTGTTTCTTTAGGTACCGGATTGCCTCCAACTACAGAATTGAAAGACATAGATGTT
TTTCGACCGGACAGCATTTGGGATACCGCAAAACTTGCATATGGTATTTCAGCAATCGGA
AATTTATTAGTAGATCAAGCGACATTAGCTGACGGACGCGTTGTAGATCGAGCGCGCGCA
TGGTGTAGTATGATCGGTGTGCCGTATTTCCGCTTTAATCCACAAATGTCAGTTGATTTA
GCGATGGATGAGAAAATGGATGCACCTCTTATAAATATGATGTGGGAGACTAAAGCTTAT
ATGTATCAAAATCGCAACAAAGTTATTGAAATGGTCAACTTATTGAAATAA
>g11362.t1 Gene=g11362 Length=896
MFSAIKNLLTGEIPPSKVIEKSLDSIASYNVLQRDDCMLLFAPQITDNSTSNTSSKSKKF
YEIILYRPASESINSSYSLFRAETQEEALARFEAYTHRVPNFVTMVNQYYNIPGLQKVCD
LLTENPSWSIAHLVAYFNLTEYLSNPAVAELIDYPDHVKYMTPLQVAIKAKNIEVVKGLL
NVTKLDHLDYNSNGIFHYAANTSKEMINILTSKSLVNLNHINLDGITPLHHACLSNNPDC
VNALVCAGADVNISAKHVNGSGKGGNKLQNRNAPSTTTSPSGTVAEFFQTNANKVCREEM
KNGGTPLHWASSREVLEVLIERGCHIDSLDFNGRSALHVMVLKNQLDCVVSLLAHEAEID
LKDKDGNTPLHIAVEKKFIPIVQCLVVFGCDINMKNKNDQTARHMVGKEASGSNDDMILY
ILHSVGAKRCPDTSTRCPVGCNAKGTYNGIPPAQPETTEQREAIQQMLATTTSQLMRGRN
SVPTIANQQLFRLPKEQPVLIDTTAEQKGQSVMDALLGMFTSKIQAAAKKEVPVCDKGTS
TAEDENVEVMEEDHECSASEEDSVNSGSRGRLLCLDGGGIRGLVLVQMLLEIEQLSQTPI
HFLFDWIAGTSTGGILALGIGSGKTMKQCMCLYLKMKNVAFNGSRPYSSDPLENVLKENL
GEHTVMAEIQHPKIMVSAVMADRKPVDLHFFRNYKTASDILNIATPTSNRRIPPPSPENQ
LIWRAARATGAAPSYFRAFGRFLDGGLIANNPTLDAMTEIHEYNMALYSVNRKNEAVPLS
IVVSLGTGLPPTTELKDIDVFRPDSIWDTAKLAYGISAIGNLLVDQATLADGRVVDRARA
WCSMIGVPYFRFNPQMSVDLAMDEKMDAPLINMMWETKAYMYQNRNKVIEMVNLLK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 11 | g11362.t1 | CDD | cd07212 | Pat_PNPLA9 | 572 | 885 | 8.08566E-174 |
| 9 | g11362.t1 | Gene3D | G3DSA:1.25.40.20 | - | 118 | 270 | 1.2E-15 |
| 8 | g11362.t1 | Gene3D | G3DSA:1.25.40.20 | - | 271 | 437 | 1.0E-29 |
| 10 | g11362.t1 | Gene3D | G3DSA:3.40.1090.10 | Cytosolic phospholipase A2 catalytic domain | 557 | 866 | 1.2E-38 |
| 19 | g11362.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 260 | 280 | - |
| 18 | g11362.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 263 | 280 | - |
| 4 | g11362.t1 | PANTHER | PTHR24139 | CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 | 3 | 896 | 5.0E-273 |
| 5 | g11362.t1 | PANTHER | PTHR24139:SF34 | 85/88 KDA CALCIUM-INDEPENDENT PHOSPHOLIPASE A2 | 3 | 896 | 5.0E-273 |
| 3 | g11362.t1 | Pfam | PF12796 | Ankyrin repeats (3 copies) | 164 | 254 | 9.8E-10 |
| 2 | g11362.t1 | Pfam | PF12796 | Ankyrin repeats (3 copies) | 307 | 396 | 6.5E-13 |
| 1 | g11362.t1 | Pfam | PF01734 | Patatin-like phospholipase | 573 | 756 | 1.1E-14 |
| 20 | g11362.t1 | ProSiteProfiles | PS50297 | Ankyrin repeat region circular profile. | 159 | 427 | 36.207 |
| 22 | g11362.t1 | ProSiteProfiles | PS50088 | Ankyrin repeat profile. | 224 | 256 | 12.209 |
| 23 | g11362.t1 | ProSiteProfiles | PS50088 | Ankyrin repeat profile. | 332 | 364 | 10.419 |
| 21 | g11362.t1 | ProSiteProfiles | PS50088 | Ankyrin repeat profile. | 365 | 397 | 12.529 |
| 24 | g11362.t1 | ProSiteProfiles | PS51635 | Patatin-like phospholipase (PNPLA) domain profile. | 573 | 757 | 28.174 |
| 13 | g11362.t1 | SMART | SM00248 | ANK_2a | 159 | 189 | 33.0 |
| 17 | g11362.t1 | SMART | SM00248 | ANK_2a | 190 | 220 | 960.0 |
| 12 | g11362.t1 | SMART | SM00248 | ANK_2a | 224 | 253 | 5.2E-7 |
| 14 | g11362.t1 | SMART | SM00248 | ANK_2a | 302 | 328 | 47.0 |
| 16 | g11362.t1 | SMART | SM00248 | ANK_2a | 332 | 361 | 0.015 |
| 15 | g11362.t1 | SMART | SM00248 | ANK_2a | 365 | 394 | 2.5E-4 |
| 7 | g11362.t1 | SUPERFAMILY | SSF48403 | Ankyrin repeat | 149 | 406 | 9.3E-43 |
| 6 | g11362.t1 | SUPERFAMILY | SSF52151 | FabD/lysophospholipase-like | 571 | 884 | 1.78E-42 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
| GO:0006629 | lipid metabolic process | BP |
KEGG
Orthology
- This transcript has been annotated with K16343 (calcium-independent phospholipase A2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
