General information for g11364.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Ribosomal protein S6 kinase beta-1.
Parent gene
- The parent gene g11364 is located on chr_1: 15812752..15813654 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11364 | g11364.t3 | TTS | g11364.t3 | 15810135 | 15810135 |
| chr_1 | g11364 | g11364.t3 | isoform | g11364.t3 | 15810684 | 15812678 |
| chr_1 | g11364 | g11364.t3 | exon | g11364.t3.exon1 | 15810684 | 15811573 |
| chr_1 | g11364 | g11364.t3 | cds | g11364.t3.CDS1 | 15811160 | 15811573 |
| chr_1 | g11364 | g11364.t3 | exon | g11364.t3.exon2 | 15811646 | 15811755 |
| chr_1 | g11364 | g11364.t3 | cds | g11364.t3.CDS2 | 15811646 | 15811755 |
| chr_1 | g11364 | g11364.t3 | exon | g11364.t3.exon3 | 15811820 | 15811888 |
| chr_1 | g11364 | g11364.t3 | cds | g11364.t3.CDS3 | 15811820 | 15811888 |
| chr_1 | g11364 | g11364.t3 | exon | g11364.t3.exon4 | 15811954 | 15812114 |
| chr_1 | g11364 | g11364.t3 | cds | g11364.t3.CDS4 | 15811954 | 15812114 |
| chr_1 | g11364 | g11364.t3 | exon | g11364.t3.exon5 | 15812179 | 15812305 |
| chr_1 | g11364 | g11364.t3 | cds | g11364.t3.CDS5 | 15812179 | 15812305 |
| chr_1 | g11364 | g11364.t3 | exon | g11364.t3.exon6 | 15812358 | 15812422 |
| chr_1 | g11364 | g11364.t3 | cds | g11364.t3.CDS6 | 15812358 | 15812422 |
| chr_1 | g11364 | g11364.t3 | exon | g11364.t3.exon7 | 15812488 | 15812542 |
| chr_1 | g11364 | g11364.t3 | cds | g11364.t3.CDS7 | 15812488 | 15812531 |
| chr_1 | g11364 | g11364.t3 | exon | g11364.t3.exon8 | 15812600 | 15812678 |
| chr_1 | g11364 | g11364.t3 | TSS | g11364.t3 | NA | NA |
Sequences
>g11364.t3 Gene=g11364 Length=1556
CATCCATTTATTGTAGAATTAGTTTATGCATTTCAAACTGGTGGAAAGTTATATTTGATT
TTAGAATATCTCAGTGGAGGTGAACTTTTTATGCATTTAGAACGTGAAGGAATATTTTTA
GAGGACACTACATGCTTTTATTTGAATGAGATAGTACTAGCATTAGAACATCTTCATTCG
CTAGGAATCATTTATAGAGACCTTAAACCAGAAAATGTCTTACTTGATGCACAAGGACAT
GTAAAATTAACGGATTTTGGACTTTGCAAAGAACATATTCATGAGGGCATAACTGCTTGG
ACGTTTTGTGGAACAATTGAATATATGGCACCTGAAATATTAACGAGGGCGGGTCATGGA
AAAGCAGTAGATTGGTGGAGTCTTGGTGCTCTCATGTATGACATGCTTACTGGTAATCCT
CCCTTTAGTGCTGAAAATAGAAAGAAAACTATTGAAACAATTCTCAAAGGAAAACTCAAT
CTTCCAGCCTATTTAACTCCAGATGCTAGAGATTTAATTCGACGCTTAATGAAAAGACAA
GTTTCACAACGCTTAGGAAGTGGTCCAAATGATGGGTTAGAAGTCCGTTCTCATCCATTT
TTCAAAAATGTAAATTGGAAAGATGTATTTGAGAGACGTCTTGAACCTCCAATTAAGCCT
GTTCTTAGAAGTGAAGATGATGTATCACAATTTGATACAAAATTTACAAAGCAAATTCCC
GTTGATTCACCTGAAGAATCTACTCTTAGTGAGAGTGCAAACATGATGTTTCAAGGTTTT
ACTTATGTTGCACCTTCTGTATTGGAGGAAATGAGCCATCAACGCATAATAACGGCTAGA
AGTCCTCGCCGTACACCACGTCATAGGGAAGATCACATGAGCCTTAGAGTTTTTCCTGGA
ACATCGACAGCCTCAATCGCCAGTCAACCACAACATTTTTACCCAAATTCTTCGCATAAT
CAAAATAACAATTCAATGCAACCGCATAGGAATCCTCTTTTTGCTGGTAATCCACATTTA
CAAGGATTTAGTAATGCTCCATCAGAAGATTCGATGTCAATGGACATAAACAACTCATAG
TTAAATAATTTCAGTTATGCATTGTGAATATAAATATATATAAATATGAATGCCATAGAA
ATTCATAATTTCTTTATGAATTTTTTCCTCTCTCATATTTGACAGCAGTGCAACTGTAAT
TAATTTTTTTATTATAAGACTATATTTTGAACGAAACAAAAAAATATAACGTTGAATTTT
CATAATTTTTTAATACAATCAAAAGAAAAGATCGAGTAAATTTTTGATTAACTGAGATAG
CGTTTTTTAATAAATTAATGGAAAGAACGCAATGATAAATAACACACTCTTAGATAGAAT
AAAAATTTTTAATTATTAAATAATACGTAATATAATTTTTTAAAACGAATTTAAAACACA
CGATAAAATTTCTTCCCCATTGTTTTGCCCACTAATTTTTAAGTTTATTGATTCAATTGA
GATATATTATAGCCAAAGCACAAAAATATGAATGAAATGATTAATAAATCAACTTG
>g11364.t3 Gene=g11364 Length=329
MHLEREGIFLEDTTCFYLNEIVLALEHLHSLGIIYRDLKPENVLLDAQGHVKLTDFGLCK
EHIHEGITAWTFCGTIEYMAPEILTRAGHGKAVDWWSLGALMYDMLTGNPPFSAENRKKT
IETILKGKLNLPAYLTPDARDLIRRLMKRQVSQRLGSGPNDGLEVRSHPFFKNVNWKDVF
ERRLEPPIKPVLRSEDDVSQFDTKFTKQIPVDSPEESTLSESANMMFQGFTYVAPSVLEE
MSHQRIITARSPRRTPRHREDHMSLRVFPGTSTASIASQPQHFYPNSSHNQNNNSMQPHR
NPLFAGNPHLQGFSNAPSEDSMSMDINNS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g11364.t3 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 2 | 191 | 1.4E-75 |
| 3 | g11364.t3 | PANTHER | PTHR24351:SF171 | RIBOSOMAL PROTEIN S6 KINASE BETA-2 | 1 | 245 | 2.8E-136 |
| 4 | g11364.t3 | PANTHER | PTHR24351 | RIBOSOMAL PROTEIN S6 KINASE | 1 | 245 | 2.8E-136 |
| 2 | g11364.t3 | Pfam | PF00069 | Protein kinase domain | 2 | 170 | 1.8E-44 |
| 1 | g11364.t3 | Pfam | PF00433 | Protein kinase C terminal domain | 193 | 232 | 1.8E-9 |
| 8 | g11364.t3 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 33 | 45 | - |
| 11 | g11364.t3 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 1 | 171 | 34.718 |
| 10 | g11364.t3 | ProSiteProfiles | PS51285 | AGC-kinase C-terminal domain profile. | 172 | 242 | 17.362 |
| 7 | g11364.t3 | SMART | SM00220 | serkin_6 | 1 | 171 | 1.8E-28 |
| 6 | g11364.t3 | SMART | SM00133 | pkinase_C_6 | 172 | 234 | 2.9E-20 |
| 5 | g11364.t3 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 2 | 230 | 1.75E-63 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004674 | protein serine/threonine kinase activity | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
